葡萄多酚微胶囊化研究进展

方芳; 王凤忠

doi:10.13386/j.issn1002-0306.2017.18.062

葡萄多酚微胶囊化研究进展

方芳,
王凤忠

中国农业科学院农产品加工研究所

基金项目:

国家自然科学基金项目(31401823)；

详细信息

作者简介:
方芳 (1980-) , 女, 博士, 副研究员, 研究方向:植物源食品功能活性物质挖掘与代谢调控研究, E-mail:fangfang9992@126.com。;

王凤忠 (1972-) , 男, 博士, 研究员, 研究方向:农产品功能因子研究与利用, E-mail:wangfengzhong@sina.com。;

中图分类号: TS261.9
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出版历程
- 收稿日期: 2017-03-12

Research progress on microencapsulation of grape polyphenols

Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences

摘要

摘要: 葡萄多酚是人类饮食中重要的天然抗氧化剂,但由于其水溶性差且极易降解,导致其生物利用率低,在食品工业中的应用受限。微胶囊技术是一种可将生物活性物质进行包埋从而实现内容物有效递送的技术,可有效提高内容物的生物利用度。近年来其在葡萄多酚包埋领域得到广泛关注。本文综述了近年来有关葡萄多酚微胶囊化研究进展,并对现存问题进行分析,对今后研究重点进行展望,以期为后续葡萄多酚稳定性提升研究提供依据。
- 葡萄 /
- 多酚 /
- 微胶囊化
Abstract: Grape polyphenols are important natural antioxidants in human diet, but its utilization in food industry is limited because of its low water solubility and easy degradation to various external environmental factors.Microencapsulation technology is a new technology which can encapsulate bioactive into carriers and helps to deliver it to the target sites, thereby to improve its bioavailability.Nowadays, microencapsulation technology has aroused great interest in the stabilization of grape polyphenols.In this paper, the latest research progress on microencapsulation of grape polyphenols was reviewed, the existing problems in the research field and the research prospect was also elaborated in order to lay a basis for the scientific research of the stabilization improvement of grape polyphenols in the future.
- grape /
- polyphenols /
- microencapsulation

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参考文献(58)

[1]	Rathi P, Rajput C.Antioxidant potential of grapes (Vitisvinifera) :A review[J].Journal of Drug Delivery&Therapeutics, 2014, 4 (2) :102-104.
[2]	Lafka T I, Sinanoglou V, Lazos E S.On the extraction and antioxidant activity of phenolic compounds from winery wastes[J].Food Chemistry, 2007, 104 (3) :1206-1214.
[3]	Rockenbach I I, Rodrigues E, Gonzaga L V, et al.Phenolic compounds content and antioxidant activity in pomace from selected red grapes (Vitis vinifera L.And Vitis labrusca L.) widely produced in Brazil[J].Food Chemistry, 2011, 127:174-179.
[4]	Davidov-Pardo G, Mc Clements D J.Nutraceutical delivery systems:resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification[J].Food Chemistry, 2015, 167:205-212.
[5]	Devesa-Ray R, Vecino X, Varela-Alende J L, et al.Valorization fo winery waste vs.the costs of not recycling[J].Waste Management, 2011, 31:2327-2335.
[6]	Lavelli V, Harsha P S C S, Laureati M, et al.Degradation kinetics of encapsulated grape skin phenolics and micronized grape skins in various water activity environments and criteria to develop wide-ranging and tailor-made food applications[J].Innovative Food Science and Emerging Technologies, 2017, 39:156-164.
[7]	Ferrazzano G F, Amato I, Ingenito A, et al.Plant polyphenols and their anti-cariogenic properties:a review[J].Molecules, 2011, 16:1486-1507.
[8]	López-Lázaro M.Distribution and biological activities of the flavonoid luteolin[J].Mini-Reviews in Medicinal Chemistry, 2009, 9:31-59.
[9]	Walle T, Hsieh F, Delegge M H, et al.High absorption but very low bioavailability of oral resveratrol in humans[J].Drug Metabolism and Disposition, 2004, 32 (12) :1377-1382.
[10]	Fernández K, Aburto J, Plessing C V, et al.Factorial design optimization and characterization of poly-lactic acid (PLA) nanoparticle formation for the delivery of grape extracts[J].Food Chemistry, 2016, 207:75-85.
[11]	Silva M C, de Souza V B, Thomazini M, et al.Use of the jabuticaba (Myrciaria cauliflora) depulping residue to produce a natural pigment powder with functional properties[J].LWT-Food Science and Technology, 2014, 55:203-209.
[12]	Teixeira A, Baenas N, Dominguez-Perles R, et al.Natural bioactive compounds from winery by-products as health promoters:a review[J].International Journal of Molecular Sciences, 2014, 15:15638-15678.
[13]	Perumalla A V S, Hettiarachchy N S.Green tea and grape seed extracts-potential applications in food safety and quality[J].Food Research International, 2011, 44 (4) :827-839.
[14]	Yamagata K, Tagami M, Yamori Y.Dietary polyphenols regulate endothelial function and prevent cardiovascular disease[J].Nutrition, 2015, 31 (1) :28-37.
[15]	Rodriguez R A, Lahoz I R, Faza O N, et al.Theoretical and experimental exploration of the photochemistry of resveratrol:beyond the simple double bond isomerization[J].Organic&Biomolecular Chemistry, 2012, 10:9175-9182.
[16]	Davidov-Pardo G, Mc Clements D J.Resveratrol encapsulation:designing delivery systems to overcome solubility, stability and bioavailability issues[J].Trends in Food Science&Technology, 2014, 38:88-103.
[17]	Jakobek L.Interactions of polyphenols with carbohydrates, lipids and proteins[J].Food Chemistry, 2015, 175:556-567.
[18]	Madene A, Jacquot M, Scher J, et al.Flavour encapsulation and controlled release-a review[J].International Journal of Food Science&Technology, 2006, 41:1-21.
[19]	García-Lomillo J, González-SanjoséM L, Del Pino-García R, et al.Antioxidant and antimicrobial properties of wine byproducts and their potential uses in the food industry[J].Journal of Agricultural and Food Chemistry, 2014, 62 (52) :12595-12602.
[20]	Walker R, Tseng A, Cavender G, et al.Physicochemical, nutritional and sensory qualities of wine grape pomace fortified baked goods[J].Journal of Food Science, 2014, 79:1811-1822.
[21]	Lavelli V, Harsha P S C S, Spigno G.Modelling the stability of maltodextrin-encapsulated grape skin phenolics used as a new ingredient in apple puree[J].Food Chemistry, 2016, 209:323-331.
[22]	张峻, 吉伟之, 陈晓云, 等.壳聚糖-海藻酸钠微胶囊对葡萄多酚控制释放的研究[J].食品科学, 2004, 25 (5) :102-104.
[23]	Gibis M, Vogt E, Weiss J.Encapsulation of polyphenolic grape seed extract in polymer-coated liposomes[J].Food&Function, 2012, 3:246-254.
[24]	Boschetto D L, Dalmolin I, de Cesaro A M, et al.Phase behavior and process parameters effect on grape seed extract encapsulation by SEDS technique[J].Industrial Crops and Products, 2013, 50:352-360.
[25]	王爱霞, 金青, 尹文华, 等.流化床制备葡萄多酚微囊的工艺研究[J].西北药学杂志, 2013, 28 (4) :403-405.
[26]	Boonchu T, Utama-ang N.Optimization of extraction and microencapsulation of bioactive compounds from red grape (Vitis vinifera L.) pomace[J].Journal of Food Science and Technology, 2015, 52 (2) :783-792.
[27]	Gibis M, Ruedt C, Weiss J.In vitro release of grape-seed polyphenols encapsulated from uncoated and chitosan-coated liposomes[J].Food Research International, 2016, 88:105-113.
[28]	Aizpurua-Olaizola O, Navarro P, Vallejo A, et al.Microencapsulation and storage stability of polyphenols from Vitis vinifera grape wastes[J].Food Chemistry, 2016, 190:614-621.
[29]	Ersus S, Yurdagel U.Microencapsulation of anthocyanin pigments of black carrot (Daucus carota L.) by spray drier[J].Journal of Food Engineering, 2007, 80 (3) :805-812.
[30]	Casta1eda-Ovando A, Pacheco-Hernández M L, PáezHernández M E, et al.Chemical studies of anthocyanins.A review[J].Food Chemistry, 2009, 113:859-871.
[31]	Burin V M, Rossa P N, Ferreira-Lima N E, et al.Anthocyanins:optimisation of extraction from Cabernet Sauvignon grapes, microencapsulation and stability in soft drink[J].International Journal of Food Science&Technology, 2011, 46:186-193.
[32]	Souza V B D, Fujita A, Thomazini M, et al.Functional properties and stability of spray-dried pigments from Bordo grape (Vitis labrusca) winemaking pomace[J].Food Chemistry, 2014, 164:380-386.
[33]	Souza V B D, Thomazini M, Balieiro J C D C, et al.Effect of spray drying on the physicochemical properties and color stability of the powdered pigment obtained from vinification byproducts of the Bordo grape (Vitis labrusca) [J].Food and Bioproducts Processing, 2015, 93:39-50.
[34]	张慧文, 张玉, 马超美.原花青素的研究进展[J].食品科学, 2015, 36 (5) :296-304.
[35]	Ei-alfy A T, Ahmed A A, Fatani A J.Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats[J].Pharmacological Research, 2005, 52 (3) :264-270.
[36]	Vaid M, Katiyar S K.Grape seed proanthocyanidins inhibit cigarette smoke condensate-induced lung cancer cell migration through inhibition of NADPH oxidase and reduction in the binding of p22 (phox) and p47 (phox) proteins[J].Molecular Carcinogenesis, 2015, 54 (s1) :E61-E71.
[37]	Song X L, Li Y M, Xiao J S, et al.Effect of grape seed proanthocyanidins on gut microbiota of diet-induced-obesity rats[J].Journal of Food Science and Technology, 2015, 5.
[38]	Ratnam D V, Ankola D, Bhardwaj V, et al.Role of antioxidants in prophylaxis and therapy:a pharmaceutical perspective[J].Journal of Controlled Release, 2006, 113 (3) :189-207.
[39]	王忠合.双层原花青素微胶囊的研究[D].广州:华南理工大学, 2006.
[40]	张连富, 牟德华, 杜彦山.原花青素提取及微胶囊化研究[J].天然产物研究与开发, 2007, 19:657-661.
[41]	吴朝霞, 孟宪军, 林琳, 等.几种微胶囊包裹方法对葡萄籽原花青素包裹效果的对比研究[J].食品工业科技, 2005, 26 (9) :67-68.
[42]	Patel K R, Scott E, Brown V A, et al.Clinical trials of resveratrol[J].Annual New York Academy of Science, 2011, 1215:161-169.
[43]	Mc Clements D J.Design of nano-laminated coatings to control bioavailability of lipophilic food components[J].Journal of Food Science, 2010, 75 (1) :R30-42.
[44]	Takahashi M, Uechi S, Takara K, et al.Evaluation of an oral carrier system in rats:bioavailability and antioxidant properties of liposome-encapsulated curcumin[J].Journal of Agricultural and Food Chemistry, 2009, 57 (19) :9141-9146.
[45]	胡荣, 罗先钦, 秦伟瀚, 等.正交实验优选白藜芦醇微囊处方[J].中国药房, 2013, 47:4449-4451.
[46]	胡荣, 杨荣平, 秦伟瀚, 等.喷雾干燥法制备白藜芦醇壳聚糖微囊的工艺研究[J].天然产物研究与开发, 2014, 26:139-141.
[47]	周冉, 岳红坤, 王飞, 等.单凝聚法制备白藜芦醇微囊的工艺优化[J].河北师范大学学报 (自然科学版) , 2013, 37 (3) :292-297.
[48]	Hertog M G L, Hollman P C H, Van de Putte B.Content of potentially anticarcinogenic flavonoids of tea infusions, wines and fruit juices[J].Journal of Agricultural and Food Chemistry, 1993, 41:1242-1246.
[49]	Due1as M, González-Manzano S, González-Paramás A, et al.Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin[J].Journal of Pharmaceutical and Biomedical Analysis, 2010, 51:443-449.
[50]	Cai X, Fang Z, Dou J, et al.Bioavailability of quercetin:problems and promises[J].Current Medicinal Chemistry, 2013, 20:2572-2582.
[51]	Odriozola-Serrano I, Soliva-Fortuny R, Martín-Belloso O.Phenolic acids, flavonoids, vitamin C and antioxidant capacity of strawberry juices processed by high-intensity pulsed electric fields or heat treatments[J].European Food Research and Technology, 2008, 228:239-248.
[52]	Almeida J S, Lima F, Ros S D, et al.Nanostructured systems containing rutin:in vitro antioxidant activity and photostability studies[J].Nanoscale Research Letters, 2010, 5 (10) :1603-1610.
[53]	Konecsni K, Low N H, Nickerson M T.Chitosantripolyphosphate submicron particles as the carrier of entrapped rutin[J].Food Chemistry, 2012, 134 (4) :1775-1779.
[54]	Jantrawut P, Assifaoui A, Chambin O.Influence of low methoxyl pectin gel textures and in vitro release of rutin from calcium pectinate beads[J].Carbohydrate Polymers, 2013, 97 (2) :335-342.
[55]	Akhtar M, Murray B S, Afeisume E I, et al.Encapsulation of flavonoid in multiple emulsion using spinning disc reactor technology[J].Food Hydrocolloids, 2014, 34:62-67.
[56]	Kerdudo A, Dingas A, Fernandez X, et al.Encapsulation of rutin and naringenin in multilamellar vesicles for optimum antioxidant activity[J].Food Chemistry, 2014, 159:12-19.
[57]	Lucas-abellán C, Fortea I, Gabaldón J A, et al.Encapsulation of quercetin and myricetin in cyclodextrins at acidic p H[J].Journal of Agricultural and Food Chemistry, 2008, 56:255-259.
[58]	Celik S E, Ozyürek M, Gü9lüK, et al.Antioxidant capacity of quercetin and its glycosides in the presence ofβ-cyclodextrins:influence of glycosylation on inclusion complexation[J].Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2015, 83:309-319.