单端孢霉烯族毒素及其去除方法研究进展

赵亚荣; 马丽艳; 王富华

doi:10.13386/j.issn1002-0306.2016.21.066

单端孢霉烯族毒素及其去除方法研究进展

1. 中国农业大学食品科学与营养工程学院
2. 广东省农业科学院农产品公共监测中心
3. 农业部农产品质量安全检测与评价重点实验室

基金项目:

农业部农产品质量安全检测与评价重点实验室开放课题项目(NK201501)；

详细信息

作者简介:
赵亚荣(1988-),女,博士研究生,研究方向:致病微生物及其控制,E-mail:zyr520zyr@163.com。;

王富华(1962-),男,本科,研究员,研究方向:农产品质量安全,E-mail:wfhwqs@163.com。;

中图分类号: TS201.3
计量
- 文章访问数: 149
- HTML全文浏览量: 16
- PDF下载量: 289
出版历程
- 收稿日期: 2016-04-07

Research progress in trichothecenes and removal method

College of Food Science and Nutritional Engineering,China Agricultural University
Public Monitoring Center for Agro-product of Guangdong Academy of Agricultural Sciences
Key Laboratory of Testing and Evaluation for Agro-product Safety and Quality,Ministry of Agriculture

摘要

摘要: 单端孢霉烯族毒素是由多种真菌产生的一类真菌毒素,广泛分布于谷物类食品中,对人和动物具有毒性效应。本文对单端孢霉烯族毒素的理化性质、污染现状、危害程度、去除措施等进行了综述,旨在为预防控制单端孢霉烯族毒素的研究提供借鉴和依据。
- 单端孢霉烯族毒素 /
- 理化性质 /
- 污染 /
- 去除方法
Abstract: Trichothecenes are mycotoxins produced by fungi,which widely distributed in cereal food and have toxic effect to human and animals.This review summarizes various aspects of trichothecenes including physicochemical properties,natural occurrence,the extent of damages and removal method,aimed at providing beneficial reference for studies that prevent and control trichothecenes.
- Trichothecenes /
- physicochemical property /
- pollution /
- removal method

HTML全文

参考文献(50)

[1]	Bennett J W,Klich M.Mycotoxins,in Encyclopedia of Microbiology[M].London:Caister Academic Press,2009:559-565.
[2]	Glenn A E.Mycotoxigenic Fusarium Species in Animal Feed[J].Animal Feed Science and Technology,2007,137(3-4):213-240.
[3]	Bhat R,Rai R V,KANIM A.Mycotoxins in Food and Feed:Present Status and Future Concerns[J].Comprehensive Reviews in Food Science and Food Safety,2010,9(1):57-81.
[4]	Aniolowska M,Steininger M.Determination of trichothecenes and zearalenone in different corn(Zea mays)cultivars for human consumption in Poland[J].Journal of Food Composition and Analysis,2014,33(1):14-19.
[5]	Kirincic S,Skrjanc B,Kos N,et al.Mycotoxins in cereals and cereal products in Slovenia-Official control of foods in the years2008-2012[J].Food Control,2015,50:157-165.
[6]	Aniolowska M,Steininger M.Determination of Trichothecenes and Zearalenone in Different Corn(Zea Mays)Cultivars for Human Consumption in Poland[J].Journal of Food Composition and Analysis,2014,33(1):14-19.
[7]	Crenar B,Petric S.Cytochrome P450 Enzymes in The Fungal Kingdom[J].BBA-Proteins Proteom,2011,1814(1):29-35.
[8]	Van De Perre E,Deschurffeleer N,Jacxsens L,et al.Screening of Moulds and Mycotoxins in Tomatoes,Bell Peppers,Onions,Soft Red Fruits and Derived Tomato Products[J].Food Control,2014,37:165-170.
[9]	Li C,Selvaraj J N,Xing Fuguo,et al.A Minor Survey of Deoxynivalenol in Fusarium Infected Wheat From YangtzeHuaihe River Basin Region in China[J].Food Control,2013,30(2):469-473.
[10]	史建荣,刘馨,仇剑波,等.小麦中镰刀菌毒素脱氧雪腐镰刀菌烯醇污染现状与防控研究进展[J].中国农业科学,2014,47(18):3641-3654.
[11]	Ji F,Xu J H,Liu X,et al.Natural Occurrence of Deoxynivalenol and Zearalenone in Wheat From Jiangsu Province,China[J].Food Chemistry,2014,157(15):393-397.
[12]	Gilbert J.Current View on The Occurrence and Significance of Fusarium Toxins[J].Journal of applied bacteriology,1989,67(18):89-98.
[13]	邹忠义,贺稚非,李洪军,等.畜禽产品中脱氧雪腐镰刀菌烯醇和T-2毒素残留分析[J].食品科学,2013(14):208-211.
[14]	Afsah-Hejri L,Jinap S,Hajeb P,et al.A Review on Mycotoxins in Food and Feed:Malaysia Case Study[J].Comprehensive Reviews in Food Science and Food Safety,2013,12(6):629-651.
[15]	Bianco G,Fontanella B,Severino L,et al.Nivalenol and Deoxynivalenol Affect Rat Intestinal Epithelial Cells:A Concentration Related Study[J].Plos One,2012,7(12):1-14.
[16]	Alassane-Kpembi I,Kolf-Clauw M,Gauthier T,et al.New Insights into Mycotoxin Mixtures:The Toxicity of Low Doses of Type B Trichothecenes on Intestinal Epithelial Cells is Synergistic[J].Toxicology and Applied Pharmacology,2013,272(1):191-198.
[17]	Zhang X J,Dohnalc V,Dohnalovad L,et al.Military Potential of Biological Toxins[J].Journal of Applied Biomedicine,2014,12(2):63-77.
[18]	Eriksen G S,Pettersson H.Toxicological Evaluation of Trichothecenes in Animal Feed[J].Animal Feed Science and Technology,2004,114(1):205-239.
[19]	Hymery N,Sibiril Y,Parent-Massin D.In Vitro Effects of Trichothecenes on Human Dendritic Cells[J].Toxicology in Vitro,2006,20(6):899-909.
[20]	Desjardins A E,Proctor R H.Molecular Biology of Fusarium Mycotoxins[J].International Journal of Food Microbiology,2007,119(1):47-50.
[21]	Pestka J J,Smolinski A T.Deoxynivalenol:Toxicology and potential effects on humans[J].Journal of Toxicology and Environmental Health,2005,8(1):39-69.
[22]	Pinton P,Oswald I P.Effect of Deoxynivalenol and Other Type B Trichothecenes on The Intestine:A Review[J].Toxins,2014,6(5):1615-1643.
[23]	Daenicke S,Keese C,Goyarts T,et al.Effects of Deoxynivalenol(DON)and Related Compounds on Bovine Peripheral Blood Mononuclear Cells(PBMC)in Vitro and in Vivo[J].Mycotoxin Research,2011,27(1):49-55.
[24]	Harvey R B,Kubena L F,Corrier D E,et al.Effects of deoxynivalenol in a wheat ration fed to growing lambs[J].American Journal of Veterinary Research,1986,47(7):1630-1632.
[25]	Stanek C,Reinhardt N,Diesing A-K,et al.A Chronic Oral Exposure of Pigs with Deoxynivalenol Partially Prevents the Acute Effects of Lipopolysaccharides on Hepatic Histopathology and Blood Clinical Chemistry[J].Toxicology Letters,2012,215(3):193-200.
[26]	Herrman T,Trigo-Stockii D.Mycotoxins in Feed Grains and Ingredients[M].Manhattan,Kansas State University,2002:1-5.
[27]	Wu Q hua,Dohnal V,Kuca K,et al.Trichothecenes:Structure-Toxic Activity Relationships[J].Current Drug Metabolism,2013,14:641-660.
[28]	Yumbe-Guevara B E,Imoto T,Yoshizawa T.Effects of Heating Procedures on Deoxynivalenol,Nivalenol and Zearalenone Levels in Naturally Contaminated Barley and Wheat[J].Food Additives and Contaminants,2003,20(12):1132-1140.
[29]	Breta M,Beyer M,Cramer B,et al.Thermal Degradation of The Fusarium Mycotoxin Deoxynivalenol[J].Journal of Agricultural and Food Chemistry,2006,54(17):6445-6451.
[30]	Beyer M,Ferse I,Mulac D,et al.Structural Elucidation of T-2 Toxin Thermal Degradation Products and Investigations toward Their Occurrence in Retail Food[J].Journal of Agricultural and Food Chemistry,2009,57(5):1867-1875.
[31]	Lesnik M,Cencic A,Vajs S,et al.Milling and Bread Baking Techniques Significantly Affect The Mycotoxin(Deoxynivalenol and Nivalenol)Level in Bread[J].Acta Alimentaria,2008,37(4):471-483.
[32]	Schenzel J R,Goss K,Schwarzenbach R,et al.Experimentally Determined Soil Organic Matter-Water Sorption Coefficients for Different Classes of Natural Toxins and Comparison with Estimated Numbers[J].Environmental Science and Technology,2012,46(11):6118-6126.
[33]	Oneill K,Damoglou A P,Patterson M F.The Stability of Deoxynivalenol and 3-Acetyl Deoxynivalenol to GammaIrradiation[J].Food Additives and Contaminants,1993,10(2):209-215.
[34]	Aziz N H,Attia E,Farag S A.Effect of Gamma-Iirradiation on The Natural Occurrence of Fusarium Mycotoxins in Wheat,Flour and Bread[J].Nahrung-Food,1997,41(1):34-37.
[35]	Calado T,Venancio A,Abrunhosa L.Irradiation for Mold and Mycotoxin Control:A Review[J].Comprehensive Reviews in Food Science and Food Safety,2014,13(5):1049-1061.
[36]	Khatibi P,Berger G,Wilson J,et al.A Comparison of Two Milling Strategies To Reduce the Mycotoxin Deoxynivalenol in Barley[J].Journal of Agricultural and Food Chemistry,2014,62(18):4204-4213.
[37]	Awad W A,Ghareeb K,Bohm J,et al.Decontamination and Detoxification Strategies for The Fusarium Mycotoxin Deoxynivalenol in Animal Feed and The Effectiveness of Microbial Biodegradation[J].Food additives&contaminants.Part A,Chemistry,analysis,control,exposure&risk assessment,2010,27(4):510-520.
[38]	Young J C.Reduction in Levels of Deoxynivalenol in Contaminated Corn by Chemical and Physical Treatment[J].Journal of Agricultural and Food Chemistry,1986,34(3):465-467.
[39]	Pestka J J.Deoxynivalenol:Toxicity,Mechanisms and Animal Health Risks[J].Animal Feed Science and Technology,2007,137(3):283-298.
[40]	King R R,Mcqueen R E,Levesque D,et al.Transformation of Deoxynivalenol(Vomitoxin)by Ruman Microorganisms[J].Journal of Agricultural and Food Chemistry,1984,32(5):1181-1183.
[41]	Eriksen G S,Pettersson H,Lundh T.Comparative Cytotoxicity of Deoxynivalenol,Nivalenol,Their Acetylated Derivatives and De-epoxy Metabolites[J].Food and Chemical Toxicology,2004,42(4):619-624.
[42]	Young J C,Zhu H H,Zhou T.Degradation of Trichothecene Mycotoxins by Aqueous Ozone[J].Food and Chemical Toxicology,2006,44(3):417-424.
[43]	Kimura M,Kaneko I,Komiyama M,et al.Trichothecene 3-O-Acetyltransferase Protects Both the Producing Organism and Transformed Yeast from Related Mycotoxins[J].Journal of Biological Chemistry,1998,273(3):1654-1661.
[44]	Desjardins A E,Mccormick S P,Appell M.StructureActivity Relationships of Trichothecene Toxins in An Arabidopsis Thaliana Leaf Assay[J].Journal of Agricultural and Food Chemistry,2007,55(16):6487-6492.
[45]	Karlovsky P.Biological Detoxification of The Mycotoxin Deoxynivalenol and Its Use in Genetically Engineered Crops and Feed Additives[J].Applied Microbiology and Biotechnology,2011,91(3):491-504.
[46]	He J W,Zhou T,Young J C,et al.Chemical and Biological Transformations for Detoxification of Trichothecene Mycotoxins in Human and Animal Food Chains:A Review[J].Trends in Food Science and Technology,2010,21(2):67-76.
[47]	Binder J,Horvath E M,Schatzmayr G,et al.Screening for Deoxynivalenol-Detoxifying Anaerobic Rumen Microorganisms[J].Cereal Research Communications,1997,25(31):343-346.
[48]	Fuchs E,Binder E M,Schatzmayr D,et al.Structural Characterization of Metabolites After the Microbial Degradation of Type A Trichothecenes by The Bacterial Strain BBSH 797[J].Food Additives and Contaminants,2002,19(4):379-386.
[49]	Niderkorn V,Morgavi D P,Pujos-Guillot E,et al.Screening of Fermentative Bacteria for Their Ability to Bind and Biotransform Deoxynivalenol,Zearalenone and Fumonisins in An in Vitro Simulated Corn Silage Model[J].Food and Chemical Toxicology,2007,24(4):406-415.
[50]	Gratz S W,Duncan G,Richardson A J.The Human Fecal Microbiota Metabolizes Deoxynivalenol and Deoxynivalenol-3-Glucoside and May Be Responsible for Urinary DeepoxyDeoxynivalenol[J].Applied and Environmental Microbiology,2013,79(6):1821-1825.