Abstract: A method was established based on Qu ECh ERS- ultra- high performance liquid chromatography- triple quadrupole mass spectrometry( UPLC- MS / MS) to simultaneously determine 10 kinds of plant growth regulators and fungicides residues in bean sprouts. The sample were extracted with 1% acidic acetonitrile,then dehydrated and cleaned using PSA,C₁₈ and GCB.The Qq Q mass spectrometer was operated in a multiplereaction monitoring mode and qualified using external standard method. The results showed that All of residues( Carbendazim,6- Benzylaminopurine,Indole- 3- acetic acid,Gibberellin,Enrofloxacin,2,4- Dichlorophenoxyacetic acid,Paclobutrazol,Prochloraz,Aldicarb,Thiophanate methyl) were in a good linear relationship between 5.0 and200.0 μg / L and the relative coefficient were more than 0.99,the recoveries were in the range of 80.4% ~99.8%,the relative standard deviations were 2.0% ~ 7.8%,the limits of detection of the method were varied from 0.2 to2.6 μg / kg. The method is simple,rapid and reliable. It can be suitable for detection and confirmation of these ten plant growth regulators and fungicides in bean sprouts products.