Research advances in toxic effect of cadmium on aquatic animals
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摘要: 重金属镉是目前水环境中长期存在的污染物,因其具有致癌、致畸和致突变等特性而被广泛关注。本文综述了镉的来源和污染现状,并分别从生理生化酶水平、分子水平、细胞组织水平阐述了镉在水生动物体内的蓄积过程、代谢规律及毒性作用。本文同时简述了镉暴露引起的水生生物氧化应激反应、脂质过氧化反应和组织病理学损伤等情况。通过分析、总结前人的研究成果,以利于今后对镉的毒性机理进行深入的研究,进而更好的控制重金属镉对水环境的污染,保护水生生物和水生生态环境,为人类提供安全的水产品提供理论依据。Abstract: Cadmium is a heavy metal which widely and long- term exist in the aquatic environment. Cadmium have attracted considerable attention in recent years because of it's mutagenicity,teratogenicity and carcinogenicity. In this paper,the sources and pollution status of cadmium were summarized. The accumulation process,metabolism process and toxic effect of cadmium in the bodies of aquatic animals were also summarized at the levels of physiology,enzyme biochemistry and molecular biology,respectively.This paper also briefly described the oxidative stress,lipid peroxidation,histopathological damages of organisms of aquatic animals after exposing to cadmium.The purposes of this paper were to provide a brief summary on the research advances in toxic effect of cadmium on aquatic animals,to give a useful reference for further study on this field,and to provide theoretical basis for controlling the cadmium pollution and supplying human people with safer aquatic products.
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Keywords:
- cadmium /
- aquatic animals /
- toxicity
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[1] Lars Jrup,Agnetakesson.Current status of cadmium as an environmental health problem[J].Toxicology and Applied Pharmacology,2009,238:201-208.
[2] Deng Guang,Li Ming,Li Hong,et al.Exposure to cadmium causes declines in growth and photosynthesis in the endangered aquatic fern(Ceratopteris pteridoides)[J].Aquatic Botany,2014,112:23-32.
[3] 常元勋.金属毒理学[M].北京:北京大学医学出版社,2008.36-42. [4] Cook M,Morrow H.Anthropogenic sources of cadmium.In:National Workshop on Cadmium Transport Into Plants[J].Canadian Network of Toxicology Centres,Ottawa,Canada,1995,June:20-21.
[5] Feng J,Shi Q,Wang X,et al.Silicon supplementation ameliorated the inhibition of photosynthesis and nitrate metabolism by cadmium(Cd)toxicity in Cucumis sativus L[J].Sci Hortic,2010,123:521-530.
[6] Ran DH,Zhang XH,Guo H.L.Primary study on the risk assessment of heavy metal pollution in river through north area of Guangdong[J].Guangdong Water Resour Hydropower,2005,6:73-77.
[7] Wang Meng-Jiao,Wang Wen-Xiong.Cadmium sensitivity,uptake,subcellular distribution and thio induction in a marine diatom:Recovery from cadmium exposure[J].Aquatic Toxicology,2011,101:387-395.
[8] 周妍英.镉对华溪蟹的损伤与低分子量壳聚糖的防护作用[D].太原:山西大学,2011. [9] 裴秀丛,徐兆发.镉的慢性毒作用及其远期效应[J].环境与职业医学,2003,20(1):58-61. [10] 黄秋婵,韦友欢,黎晓峰.镉对人体健康的危害效应及其机理研究进展[J].安徽农业科学,2007,35(9):2528-2531. [11] 邓新温璐璐迟鑫姝.镉对人体健康危害及防治研究进展[J].中国医疗前沿,2010,5(10):4-5. [12] 崔玉静,黄益宗,朱永官.镉对人类健康的危害及其影响因子的研究进展[J].卫生研究,2006,35(5):656-659. [13] Filipic Metka.Mechanisms of cadmium induced genomic instability[J].Mutation Research,2012,733:69-77.
[14] Bertin G,Averbeck D.Cadmium:cellular effects,modifications of biomolecules modulation of DNA repair and genotoxic consequences(a review)[J].Biochimie,2006,88:1549-1559.
[15] Templeton Douglas M,Liu Ying.Multiple roles of cadmium in cell death and survival[J].Chemico-Biological Interactions,2010,188:267-275.
[16] Chandurvelan Rathishri,Marsden Islay D,Sally Gaw.Waterborne cadmium impacts immunocytotoxic and cytogenotoxic endpoints in green-lipped mussel,Perna canaliculus[J].Aquatic Toxicology,2013,142:283-293.
[17] 张翠,翟毓秀,宁劲松.镉在水生动物体内的研究概况[J].水产科学,2007,26(8):465-470. [18] 龚倩.海水滩涂贝类中重金属镉的检测及富集规律的研究[D].青岛:中国海洋大学,2011. [19] 陈贵良,姚林,张艳淑.镉对鲫鱼主要脏器中锌、铜含量的影响[J].环境与职业医学,2004,21(4):332-333. [20] 马文丽,王兰,何永吉.镉诱导华溪蟹不同组织金属硫蛋白表达及镉蓄积的研究[J].环境科学学报,2008,28(6):1192-1197. [21] 王茜,王兰,席玉英.镉对长江华溪蟹的急性毒性与积累[J].山西大学学报:自然科学版,2003,26(2):176-178. [22] 朱玉芳,崔勇华,戈志强,等.重金属元素在克氏原螯虾体内的生物富集作用[J].水利渔业,2003,23(1):11-12. [23] Liu Dongmei,Yang Jian,Wang Lan.Cadmium induces ultrastructural changes in the hepatopancreas of the freshwater crab Sinopotamon henanense[J].Micron,2013,47:24-32.
[24] 柏世军.水环境镉对罗非鱼的毒性作用和机理探讨[D].杭州:浙江大学,2006. [25] 田鹏.水体中镉暴露对草鱼的氧化胁迫研究[D].重庆:西南大学,2013. [26] 柏世军,许梓荣.镉对黄颡鱼鳃线粒体结构和能量代谢的影响[J].应用生态学报,2006,17(7):1213-1217 [27] 马丹旦,雷雯雯,吴昊,等.急性镉染毒对河南华溪蟹精子质量的影响[J].环境科学学报,2013,33(7):2044-2049. [28] Lei Wenwen,Wang Lan,Liu Dongmei.Histopathological and biochemical alternations of the heart induced by acute cadmium exposure in the freshwater crab,Sinopotamon yangtsekiense[J].Chemosphere,2011,84:689-694.
[29] 丁磊,蔡春芳,吴萍,等.镉对鲫血红蛋白的影响[J].水利渔业,2002,25(3):102-111. [30] Chora S,Stmita-Geribaldi M,Guigonis J M,et al.Effect of cadmium in the clam Ruditapes decussatus assessed by proteomic analysis[J].Aquat Toxicol,2009,94:300-308.
[31] Pretto Alexandra,Loro Vania Lucian,Vera Maria Morsch.Alterations in carbohydrate and protein metabolism in silver catfish(Rhamdia quelen)exposed to cadmium[J].Ecotoxicology and Environmental Safety,2014,100:188-192.
[32] Dang Fei,Wang Wen-Xiong.Assessment of tissue-specific accumulation and effects of cadmium in a marine fish fed contaminated commercially produced diet[J].Aquatic Toxicology,2009,95:248-255.
[33] 惠天朝,王家刚,朱荫湄,等.镉对罗非鱼脑ACh E及组织中代谢酶的影响[J].浙江大学学报:农业与生命科学版,2004,30(6):673-678. [34] 轩瑞晶.镉对华溪蟹糖和蛋白质分解代谢的影响机制研究[D].太原:山西大学,2013. [35] 蒋闰兰,肖佰财,禹娜.多环芳烃对水生动物毒性效应的研究进展[J].海洋渔业,2014,36(4):372-383. [36] Horng G Y,Lin H C,Lee W.A reproductive toxicology study of phenanthrene in medaka(Oryzias latipes)[J].Archives of Environmental Contamination and Toxicology,2010,58(1):131-139.
[37] Koutsogiannaki Sophia,Franzellitti Silvia,Fabbri Elena.Oxidative stress parameters induced by exposure to either cadmium or 17-estradiol on Mytilus galloprovincialis hemocytes.The role of signaling molecules[J].Aquatic Toxicology,2014,146:186-195.
[38] Boudet Leila Chiodi,Paula Polizzi,Romero Mar'a Bele.Lethal and sublethal effects of cadmium in the white shrimp Palaemonetes argentinus:A comparison between populations from contaminated and reference sites[J].Ecotoxicology and Environmental Safety,2013,89:52-58.
[39] Vincent-Hubert Francoise,Amélie Chatel,Catherine Gourlay-Francé.Metallothionein mRNA induction is correlated with the decrease of DNA strand breaks in cadmium exposed zebra mussels[J].Mutation Research,2014,766:10-15.
[40] Wang Jinxiang,Wang Qian,Li Jiarui.Cadmium induces hydrogen peroxide production and initiates hydrogen peroxidedependent apoptosis in the gill of freshwater crab,Sinopotamon henanense[J].Comparative Biochemistry and Physiology,Part C,2012,156:195-201.
[41] Lushchak Volodymyr I.Environmentally induced oxidative stress in aquatic animals[J].Aquatic Toxicology,2011,101:13-30.
[42] 廖琳.海豚肝脏中元素含量及铜、镉化学形态的研究[D].成都:四川大学,2002. [43] 管晓娟.甲壳动物体液免疫相关酶及免疫因子研究概况[J].生命科学仪器,2009,7(4):3-7. [44] El-Sayed Yasser S,Ashry Khalid E,EL-Gazzar Ahmed M.Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia,Oreochromis Niloticus L.,Exposed to Sublethal Doses of Cadmium[J].Alexandria Journal of Veterinary Sciences,2014,40:29-43.
[45] Qu R.-J,Wang X.-H,Feng M-B.The toxicity of cadmium to three aquatic organisms(Photobacterium phosphoreum,Daphnia magna and Carassius auratus)under different p H levels[J].Ecotoxicology and Environmental Safety,2013,95:83-90.
[46] 李文艳,康现江,穆淑酶,等.镉对虾蟹毒性效应的研究进展[J].水产科学,2008,27(1):47-50. [47] 王丽丽,夏斌,陈碧娟,等.镉胁迫对虾夷扇贝抗氧化防御系统的影响[J].海洋环境科学,2012,31(1):39-43. [48] Cheol Young Choi,An Wook Kwang,Nelson Erik R.Cadmium affects the expression of metallothionein(MT)and glutathione peroxidase(GPX)mRNA in goldfish,Carassius auratus.[J].Comparative Biochemistry and Physiology,Part C,2007,145:595-600.
[49] 蔡震峰,任凤莲.金属硫蛋白的研究进展[J].应用化工,2007,36(2):187-190. [50] Chandurvelan Rathishri,D Marsden Islay,Gaw Sally.Biochemical biomarker responses of green-lipped mussel,Perna canaliculus,to acute and subchronic waterborne cadmium toxicity[J].Aquatic Toxicology,2013,140-141:303-313.
[51] 李敏.水产品中镉污染的安全评价及其不同形态的影响研究[D].青岛:中国海洋大学,2008. [52] Qin Qin,Qin Shengjuan,Wang Lan.Immune responses and ultrastructural changes of hemocytes in freshwater crab Sinopotamon henanense exposed to elevated cadmium[J].Aquatic Toxicology,2012,106:140-146.
[53] 秦圣娟.镉对华溪蟹的免疫毒性效应[D].太原:山西大学,2011. [54] Nicola Franchi,Loriano Ballarin.Influence of cadmium on the morphology and functionality of haemocytes in the compound ascidian Botryllus schlosseri[J].Comparative Biochemistry and Physiology,Part C,2013,158:29-35.
[55] 赵大显,陈立侨.中华绒螯蟹免疫相关基因的研究进展[J].水产科学,2010,29(4):243-247. [56] Alvarez Javier V,Sook Chung J.Cloning of prophenoloxidase from hemocytes of the blue crab,Callinectes sapidus and its expression and enzyme activity during the molt cycle[J].Fish&Shellfish Immunology,2013,35:1349-1358.
[57] Amparyup Piti,Charoensapsri Walaiporn,Tassanakajon Anchalee.Prophenoloxidase system and its role in shrimp immune responses against major pathogens[J].Fish&Shellfish Immunology,2013,34:990-1001
[58] Wang Xian-Wei,Zhang Hong-Wei,Li Xiang.Characterization of a C-type lectin(Pc Lec2)as an upstream detector in the prophenoloxidase activating system of red swamp crayfish[J].Fish&Shellfish Immunology,2011,30:241-247.
[59] Wang Xian-Wei,Wang Jin-Xing.Pattern recognition receptors acting in innate immune system of shrimp against pathogen infections[J].Fish&Shellfish Immunology,2013,34:981-989.
[60] Alvarez Javier V,Sook Chung J.Cloning of prophenoloxidase from hemocytes of the blue crab,Callinectes sapidus and its expression and enzyme activity during the molt cycle[J].Fish&Shellfish Immunology,2013,35:1349-1358.
[61] Li Fuhua,Xiang Jianhai.Recent advances in researches on the innate immunity of shrimp in China[J].Developmental and Comparative Immunology,2013,39:11-26.
[62] Chi Heng,Zhang Zuobing,Bgwald Jarl.Cloning,expression analysis and promoter structure of TBK1(TANK-binding kinase1)in Atlantic cod(Gadus morhua L.)[J].Fish&Shellfish Immunology,2011,30:1055-1063.
[63] Mu Changkao,Song Xiaoyan,Zhao Jianmin.A scallop C-type lectin from Argopecten irradians(Ai CTL5)with activities of lipopolysaccharide binding and Gram-negative bacteria agglutination[J].Fish&Shellfish Immunology,2012,32:716-723.
[64] Zhang Xiao-Wen,Liu Ying-Ying,Mu Yi.Overexpression of a C-type lectin enhances bacterial resistance in red swamp crayfish Procambarus clarkii[J].Fish&Shellfish Immunology,2013,34:1112-1118.
[65] Yu Shanshan,Yang Hui,Chai Yingmei.Molecular cloning and characterization of a C-type lectin in roughskin sculpin(Trachidermus fasciatus)[J].Fish&Shellfish Immunology,2013,34:582-592.
[66] Liu Dongmei,Yan Bo,Yang Jian.Mitochondrial pathway of apoptosis in the hepatopancreas of the freshwater crab Sinopotamon yangtsekiense exposed to cadmium[J].Aquatic Toxicology,2011,105:394-402.
[67] Gao Dian,Xu Zhen’e,Zhang Xiaoyan.Molecular cloning,immunohistochemical localization,characterization and expression analysis of caspase-9 from the purse red common carp(Cyprinus carpio)exposed to cadmium[J].Aquatic Toxicology,2013,142:53-62.
[68] Park Sun-Young,Gopalakrishnan Nair Prakash M,Choi Jinhee.Characterization and expression of superoxide dismutase genes in Chironomus riparius(Diptera,Chironomidae)larvae as a potential biomarker of ecotoxicity[J].Comparative Biochemistry and Physiology,Part C.2012,156:187-194.
[69] Liu Chun-Hung,Tseng Mei-Chen,Cheng Winton.Identification and cloning of the antioxidant enzyme,glutathione peroxidase,of white shrimp,Litopenaeus vannamei,and its expression following Vibrio alginolyticus infection[J].Fish&Shellf,ish Immunology,2007,23:34-45.
[70] Gao Qiang,Song Linsheng,Duojiao Ni.c DNA cloning and mRNA expression of heat shock protein 90 gene in the haemocytes of Zhikong scallop,Chlamys farreri[J].Comparative Biochemistry and Physiology,Part B,2007,147(4):704-715.
[71] Farcy Emilie,Serpentini Antoine,Fiévet Bruno.Identification of c DNAs encoding HSP70 and HSP90 in the abalone Haliotis tuberculata:Transcriptional induction in response to thermal stress in hemocyte primary culture[J].Comparative Biochemistry and Physiology,Part B,2007,146:540-550.
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