普洱茶茶色素对小鼠的预防肥胖作用

苏静静; 王雪青; 宋文军; 白晓丽; 李长文; 周彤; 罗崇景; 徐金葵; 赵心怡; 陈钊琦; 王爽

doi:10.13386/j.issn1002-0306.2014.19.067

普洱茶茶色素对小鼠的预防肥胖作用

1. 天津市食品与生物技术重点实验室,天津商业大学生物技术与食品科学学院
2. 云南天士力帝泊洱生物茶集团有限公司

基金项目:

云南天士力帝泊洱生物茶集团有限公司(20100908)；天津市教委高等学校科技发展基金计划项目(20120603)；天津商业大学大学生研究训练计划(SRT)基金项目；

详细信息

作者简介:
苏静静 (1988-) , 女, 硕士研究生, 研究方向:减肥降糖功能食品。;

王雪青 (1964-) , 女, 博士, 教授, 主要从事天然活性物质的研究与开发。;

中图分类号: R151;TS275.4
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出版历程
- 收稿日期: 2014-02-16

Prevention of pigments from Pu Erh tea on the weight growth of mouse

Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce
Yunnan Tasly Deepure Biological Tea Group Company Limited

摘要

摘要: 昆明种雄性小鼠随机分为正常对照组、高脂对照组、普洱茶茶色素低（0.45g/kg）、中（0.90g/kg）、高（1.35g/kg）浓度组。每天灌胃给药,称体重及测体长,连续灌胃29d后,禁食24h,取血测血清中的血糖（Glu）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）和高密度脂蛋白胆固醇（HDL-C）水平;处死小鼠,记录体内脂肪湿重,计算小鼠的Lee’s指数和脂体比,以研究普洱茶茶色素对小鼠的预防肥胖作用。结果显示:普洱茶茶色素能显著降低小鼠的体重、脂体比、Lee’s指数和脂肪系数（p<0.05）,显著降低小鼠血清中Glu、TG、TC、LDL-C的水平（p<0.05）,升高HDL-C的水平（p<0.05）。因此,普洱茶茶色素对小鼠具有预防肥胖、降血糖及调节血脂的作用,可作为预防和治疗肥胖症、II型糖尿病及血症异常的功能性饮品。
- 普洱茶 /
- 茶色素 /
- 肥胖 /
- 血脂
Abstract: Male Kunming mice were randomly divided into normal, high- fat diet control group, and three levels groups treated with high ( 1.35 g /kg) , medium ( 0.90 g /kg) , and low ( 0.45 g /kg) pigments from Pu Erh tea. The changes of body weight and length of the mouse were determined every day, respectively.The levels of glucose ( Glu) , total cholesterol ( TC) , triglyceride ( TG) , high-density lipoprotein cholesterol ( HDL-C) , and low-density lipoprotein cholesterol ( LDL-C) in the serum were determined when each group was fasted for 24 h after continuous administration of 29 day, the wet weights of visceral fat of five groups were measured and the Lee's index and body fat percentage of five groups were calculated in order to observe the prevention of pigments on the weight growth of mice.The results showed that Pu Erh tea pigments had significantly effects on losing body weight, fat index, body fat percentage, and reducing Lee's index, decreasing the levels of Glu, TC, TG, LDL- C, and increasing the level of HDL- C ( p < 0.05) . Thus, Pu Erh tea pigments had the functions of preventing obesity, glucose- lowering and lipid- regulating. It could be used as a potential function drink for prevention and /or treatment of obesity, type II diabetes and dyslipidemia.
- Pu Erh tea /
- pigments /
- obesity /
- lipids

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