Abstract: In this paper,the process on photocatalytic degradation of patulin was studied to evaluate the performance of photocatalytic degradation of patulin in apple juice by titanium dioxide nanotubes. First,titanium dioxide nanotubes were prepared by hydrothermal method,and the effects on the degradation of patulin of various factors including UV lamp power,reaction temperature,pH,and dosage of titanium dioxide nanotubes were investigated,with the time taken for photocatalytic degradation of patulin as an activity evaluation index. Based on this,an orthogonal experiment was designed to optimize the process of photocatalytic degradation of patulin by titanium dioxide nanotubes. The results showed that:The comparison of the photocatalytic activity of titanium dioxide nanotubes and titanium dioxide to degrade patulin in simulated juice showed that titanium dioxide nanotubes exhibited higher photocatalytic activity than titanium dioxide. The best process on photocatalytic degradation of patulin by titanium dioxide nanotubes was that the dosage of titanium dioxide nanotubes was 500 mg/L,the UV lamp power was 21 W,and the reaction temperature was 25℃. Under the optimal process conditions,when the initial concentration of patulin in the reaction system was 1000 μg/L,the comparison of the photocatalytic activity of titanium dioxide nanotubes to degrade patulin in simulated juice and apple juice showed that the time taken to reduce the patulin content below the detection limit was 25 min and 45 min respectively.