Abstract: Chia seed is rich in high-quality protein which includes 8 essential amino acids. Chia seed protein has many excellent functional properties such as emulsibility and foamability, and the prepared active peptide has biological properties such as anti-oxidation and anti-hypertension. The research progress on amino acid composition, separation and extraction process, functional properties, preparation of bioactive peptides and their physiological functions of chia seed protein in recent years are reviewed. In addition, the future perspective of its application in food industry is prospected.