Abstract: The eugenol nanoparticles were prepared by self-assembly method.The gelatin-chitosan nanoparticles, eugenol solution and blank treatment were used as the control group.The chilled pork was treated by coating method and was then processed with preservatives, p H, water holding capacity, volatile base nitrogen ( TVB-N) , thiobarbituric acid ( TBARS) value and the total number of colonies and other indicators were detected.The effect of eugenol nanoparticles on the p H, TVB-N value and TBARS value of chilled pork was significantly higher than that of eugenol treatment group ( p < 0.05) .The red a-value of eugenol nanoparticles treated group was higher than that of eugenol and gelatin-chitosan treatment group.The results showed that eugenol nanoparticles could retard the decrease of water holding capacity, texture index, springiness and cohesiveness effectively.The total number of colony experiments showed that the storage period of eugenol nanoparticles treatment group could be extended to 13 d, which was significantly different from ( p < 0.05) that in the control group ( 6 d) . Thus, eugenol nanoparticles has a good anti-corrosion, anti-oxidation effect on preservation of chilled pork.