Abstract: Tuna is a kind of expensive raw aquatic products, which has good flavor and abundant nutrition.However, the quality of tuna is easy to deteriorate. And the nutritional quality of tuna is closely related to preservation methods. Low temperature logistics could prolong the shelf life of raw aquatic products by slowing the metabolism of spoilage microorganisms.Nevertheless, there are still some cold-adapted microorganisms existed, especially Pseudomonas spp., which can take a continuous growth in low temperature environment. This paper summarized the tuna chilling storage technology and systematically expounded the adaptation mechanism of Pseudomonas spp.in low temperature through the regulation of cell membrane, cold-adapted enzymes, cold shock protein and trehalose.The study of cold-adapted mechanism of Pseudomonas spp.can be used to guide targeted tuna storage and preservation technology.