Abstract: Some research advances on main active substance of Acanthopanax, including glycosides,polysaccharides,flavonoids and other elements had been introduced briefly. Their pharmacological actions contain anti- tumor, anti- fatigue, hypoglycemic, protecting blood vessel of brain were also reported. The applications of Acanthopanax in food and medince which not only provide a reference for the further research of Acanthopanax but also make a big move for the development of its healthcare productions were also dicussied.