Abstract: Dewaxing process was an important part of pretreatment process for wolfberry drying. It affects the drying rate and the quality of wolfberry. In order to get shorter drying time and better drying quality,the effect of temperature,time and solution ratio on drying time and drying quality was studied through single factor experiment and central composite experiment. The results showed that the optimal dewaxing parameters were as follows:dewaxing time 12 min,dewaxing temperature 38 ℃,dewaxing solution ratio 1∶2. Under this situation the drying time was 21.5 h. The verification test and the quality identification results showed that optimal dewaxing process shortens drying time and retains nutrients.