Abstract: Ciguatoxin ( CTX) is an important form of marine fish poisoning. In recent years, food poisoning due to ciguatoxin in China showed an increasing trend. The origin, distribution, vector, chemical construction, toxicity, detecting and controlling technology of ciguatoxin were summarized in this paper.It will provide the references for building detecting method of ciguatoxin in marine fish, establishing the system of monitoring and early warning, improving the safety of food.