Abstract: The oratosquilla oratoria salt- soluble proteins were phosphorylated with sodium tripoly phosphate( STP)to improve the functional properties of the salt- soluble protein.On the basis of single- factor investigation,response surface methodology was employed to establish optimum conditions for the oratosquilla oratoria salt- soluble protein of phosphorylation.The best conditions of phosphorylation were 4% of STP,p H8.5,reaction temperature of30 ℃ and reaction time of 2.5 h,the degrees of phosphorylation could reach 4.715 μg / mg,the relative error value was 0.15% with the theory prediction value( 4.722 μg / mg). Compared with not phosphorylation proteins,the emulsifying activity,emulsion stability,foaming properties,foam stability of the oratosquilla oratoria salt- soluble proteins were increased by 61.90%,23.99%,88.57%,25.42% respectively.