Abstract: α-amylase is one of the key enzymes, which has been widely used in food, textile, paper making, feed and other fields.But there are always some problems occurred in the process of treatment, such as poor stability and adaptability, low enzyme activity, poor reproducibility etc.In order to solve these problems, people are constantly trying to find some modified methods for α-amylase.Therefore, this paper reviewed and summarized the modification technologies of α- amylase treated by biological modification, chemical modification and physical modification in resent years, so as to provide some references for the further research and application of α-amylase modification.