Abstract: Organophosphorus pesticide residues in Lycium barbarum L. affect products' quality. Degradation of four kinds of organophosphorus pesticides, such as dichlorvos, dimethoate, malathion and triazophos, in Lycium barbarum L. were investigated by using ozone and alkali liquor respectively, Experimental results showed that both ozone and alkali liquor could degrade these four organophosphorus pesticides, degradation rate of dichlorvos in Lycium barbarum L. reached to 97.83% by using ozone, and the degradation rate reached to 98.68% by using alkali liquor.