Abstract: Schisandra chinensis was took as raw material, the yield of polysaccharide as index, Schisandrae chinensis polysaccharide was extracted by studying three kinds of methods which including water extraction, enzymatic extraction and ultrasonic assisted, optimum extraction conditions of polysaccharide was studied by orthogonal experiment. Results showed that:the yield of Schisandrae polysaccharide extracted by ultrasonic assisted was more than the enzymatic method and the water extraction process. Optimum conditions were as follows:the ratio of solid to liquid 1 ∶25, ultrasonic time 40min, ultrasonic power 600W, extraction temperature 55℃. The yield of polysaccharide was 4.67%.