Abstract: Auricularia auricular was used as the materials and got mycelia Ge riched by using of submerged liquid cultivation in different concentration of Ge, through the determination of mycelia biological indicators to find the effects of Ge concentration to the main composition of the Auricularia auricula.The result showed that as the Ge concentration was at 400μg/mL in the culuture medium, mycelia biomass, the contents of polysaccharide, protein, guanosine and cytidine reached the peak, 10.11, 106.80, 117.52, 10.59, 11.65mg/g, respectively.As compared with the control blank, the mycelia biomass, the contents of polysaccharide, protein, guanosine and cytidine increased by 10.86%, 16.56%, 15.27%, 49.58%, 29.36%, respectively.When Ge concentration was 600μg/mL, the content of amino acids reached the highest up to 82.18mg/g, when increased 11.58% compared with the control blank.When organic germanium concentration was 800μg/mL, organic germanium content reached 8.67mg/g, and it was 57.8 times of the corresponding control.The content of organic germanium increased with the rise of the Ge concentration increases in the range of this test of Ge concentration.The content of intracellular polysaccharide, amino acid, protein, guanosine and cytidine of Auricularia auricular all along with the rise of the Ge concentration on first increased and then decreased tendency.Ge could improve the content above the index when Ge concentration was low, and could inhibition the content as Ge concentration was high.