Abstract: Phyllanchus emblica L.was used as material to extract efficiency antibacterial component with the different dissolvent.The certain concentration of alcohol was chosen as solvent extraction according to antibacterial effect, cost and toxic factors.The result of the extracting solvent, powder fineness, ratio of material to solvent, extracting temperature and time was got through single factor test.The extract concentration, temperature and time were analysed by orthogonal experiment, and results showed that the optimum extracting technology as follows:extracting solvent of 90% alcohol, extracting temperature of 50℃, and the extracting time of 4h.Under this condition, the antibacterial activity by extract acting on some sorts of bacterium was significantly enhanced, and the diameters of the bacteriostasis circles reached up to 16.9mm.