Research Progress on Functional Active Components and Its Efficacy in Rice Bran

LI Xiangfei; SHEN Dan; HUANG Junkai; LU Yingjian

doi:10.13386/j.issn1002-0306.2021070310

Volume 43 Issue 13

Jun. 2022

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Science and Technology of Food Industry > 2022 > 43(13): 466-474. > DOI: 10.13386/j.issn1002-0306.2021070310

LI Xiangfei, SHEN Dan, HUANG Junkai, et al. Research Progress on Functional Active Components and Its Efficacy in Rice Bran[J]. Science and Technology of Food Industry, 2022, 43(13): 466−474. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021070310.

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Research Progress on Functional Active Components and Its Efficacy in Rice Bran

College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing 210023, China

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Received Date: July 26, 2021
Available Online: April 22, 2022

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Abstract

Rice bran is a kind of agricultural by-product, which is rich in renewable organic carbon sources and mainly used in feed and fertilizer production today. It has been reported that rice bran is rich in various active ingredients such as dietary fiber, polyphenols and polysaccharides, which have significant physiological activities such as anti-oxidation, lowering blood lipid and blood sugar. This paper starts with the bioactive components of rice bran, analyzes its the functional properties of rice bran and its active components in anti-oxidation, hypoglycemia, anti-obesity, hypolipidemic, immunomodulating, antitumor, etc, in order to improve the application value of the bioactive components of rice bran and provide theoretical basis for the effective utilization and industrialization of the following agricultural by-products.
- rice bran,
- rice bran polysaccharide,
- rice bran polyphenols,
- improve obesity,
- inhibiting tumor

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[1]	周显青, 杨继红, 张玉荣. 国内外米糠资源利用现状与发展[J]. 粮食加工,2014,39(5):24−29. [ZHOU X Q, YANG J H, ZHANG Y R. Status and prospect of the utilization of rice bran resource at home and abroad[J]. Grain Processing,2014,39(5):24−29. ZHOU X Q, YANG J H, ZHANG Y R. Status and prospect of the utilization of rice bran resource at home and abroad[J]. Grain Processing, 2014, 39(5), 24-29.
[2]	肖信锦, 李阳洋, 钟盛华. 米糠中油脂与蛋白提取技术研究进展[J]. 粮食与油脂,2016,29(3):1−4. [XIAO X J, Ll Y Y, ZHONG S H. Advance research on extraction technology of oil and protein from rice bran[J]. Cereals & Oils,2016,29(3):1−4. doi: 10.3969/j.issn.1008-9578.2016.03.001 XIAO X J, Ll Y Y, ZHONG S H. Advance research on extraction technology of oil and protein from rice bran[J]. Cereals & Oils, 2016, 29(3), 1-4. doi: 10.3969/j.issn.1008-9578.2016.03.001
[3]	许旭. 米糠多糖的提取、免疫调节活性及其口含片制备工艺研究[D]. 武汉: 武汉轻工大学, 2014, 1−67. XU X. The extraction immunomodulatory activity testing and buccal tablet preparation of rice bran polysaccharide[D]. Wuhan: Wuhan Polytechnic University, 2014, 1−67.
[4]	吕诗文. 利用稻米副产物米糠联产米糠油、米糠蛋白和4-乙烯基愈创木酚[D]. 大连: 大连理工大学, 2018, 1−66. LÜ S W. Co-production of rice bran oil, rice bran protein and 4-vinylguaiacol from rice bran (rice by-product)[D]. Dalian: Dalian University of Technology, 2018, 1−66.
[5]	TOGASHI Y, INOMATA N, SUZUKI A, et al. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop[J]. Allergology Jnternational:Official Journal of the Japanese Society of Allergology,2019,68(1):117−118. doi: 10.1016/j.alit.2018.05.010
[6]	SHEN J, YANG T, XU Y, et al. delta-tocotrienol, isolated from rice bran, exerts an anti-inflammatory effect via MAPKs and PPARs signaling pathways in lipopolysaccharide-stimulated macrophages[J]. International Journal of Molecular Sciences,2018,19(10):3022. doi: 10.3390/ijms19103022
[7]	DENARDI-SOUZA T, LUZ C, MANES J, et al. Antifungal effect of phenolic extract of fermented rice bran with Rhizopus oryzae and its potential use in loaf bread shelf life extension[J]. Journal of the Science of Food and Agriculture,2018,98(13):5011−5018. doi: 10.1002/jsfa.9035
[8]	SHARIF M K, BUTT M S, ANJUM F M, et al. Rice bran: A novel functional ingredient[J]. Crit Rev Food Sci Nutr,2014,54(6):807−816. doi: 10.1080/10408398.2011.608586
[9]	ISLAM M S, NAGASAKA R, OHARA K, et al. Biological abilities of rice bran-derived antioxidant phytochemicals for medical therapy[J]. Current Topics in Medicinal Chemistry,2011,11(14):1847−1853. doi: 10.2174/156802611796235099
[10]	LAKKAKULA N R, LIMA M, WALKER T. Rice bran stabilization and rice bran oil extraction using ohmic heating[J]. Bioresource Technology,2004,92(2):157−161. doi: 10.1016/j.biortech.2003.08.010
[11]	严薇, 邓丽莎, 王燕, 等. 基于红外辐射处理的米糠多糖组分、提取率及抗氧化活性的影响[J]. 食品科学,2020,41(15):158−163. [YAN W, DENG L S, WANG Y, et al. Effect of infrared radiation on composition, extraction yield and antioxidant properties of polysaccharides from rice bran[J]. Food Science,2020,41(15):158−163. YAN W, DENG L S, WANG Y, et al. Effect of infrared radiation on composition, extraction yield and antioxidant properties of polysaccharides from rice bran[J]. Food Science, 2020, 41(15), 158-163.
[12]	王仲礼. 国外对米糠深加工产品的开发应用[J]. 中国稻米,2005(3):49−51. [WANG Z L. Development and utilization of deep processing products of rice bran in abroad[J]. China Rice,2005(3):49−51. doi: 10.3969/j.issn.1006-8082.2005.03.032 WANG Z L. Development and utilization of deep processing products of rice bran in abroad[J]. China Rice, 2005(3), 49-51. doi: 10.3969/j.issn.1006-8082.2005.03.032
[13]	赵倩, 熊善柏, 邵小龙, 等. 米糠多糖的提取及其性质和结构[J]. 中国粮油学报,2008(3):4−7. [ZHAO Q, XIONG S B, SHAO X L, et al. Extraction, properties and structure of polysaccharide from rice bran[J]. Journal of the Chinese Cereals and Oils Association,2008(3):4−7. ZHAO Q, XIONG S B, SHAO X L, et al. Extraction, properties and structure of polysaccharide from rice bran[J]. Journal of the Chinese Cereals and Oils Association, 2008, (3), 4-7.
[14]	鄢宏浩, 蔡乔宇, 陈轩, 等. 米糠多糖的提取纯化及生理功能活性研究进展[J]. 食品科技,2020,45(10):197−201. [YAN H H, CAI Q Y, CHEN X, et al. Research progress in extraction, purification and physiological function activity of rice bran polysaccharid[J]. Food Science and Technology,2020,45(10):197−201. YAN H H, CAI Q Y, CHEN X, et al. Research progress in extraction, purification and physiological function activity of rice bran polysaccharid[J]. Food Science and Technology, 2020, 45(10), 197-201.
[15]	喻远东, 廖卢艳. 米糠整体利用研究进展[J]. 河北农业科学,2019,23(4):69−76. [YU Y D, LIAO L Y. Advances in comprehensive utilization of rice bran[J]. Journal of Hebei Agricultural Sciences,2019,23(4):69−76. YU Y D, LIAO L Y. Advances in comprehensive utilization of rice bran[J]. Journal of Hebei Agricultural Sciences, 2019, 23(4), 69-76.
[16]	胡国华, 马正智, 吴彬. 米糠多糖的保健功能;第三届全国粳稻米产业大会, 中国吉林长春, 2008[C]. HU G H, MA Z Z, WU B. Health care function of rice bran polysaccharide; The 3rd national japonica rice industry conference, Changchun, Jilin, China, 2008[C].
[17]	HAN W, LI J, DING Y, et al. Structural features, antitumor and antioxidant activities of rice bran polysaccharides using different extraction methods[J]. J Food Sci,2017,82(10):2403−2410. doi: 10.1111/1750-3841.13776
[18]	刘梁, 孙维矿, 赵玲, 等. 米糠多糖的免疫增强作用[J]. 食品研究与开发,2014,35(22):24−28. [LIU L, SUN W K, ZHAO L, et al. The effect of immune enhancement of rice bran polysaccharide[J]. Food Research and Development,2014,35(22):24−28. doi: 10.3969/j.issn.1005-6521.2014.22.09 LIU L, SUN W K, ZHAO L, et al. The Effect of immune enhancement of rice bran polysaccharide[J]. Food Research and Development, 2014, 35(22), 24-28. doi: 10.3969/j.issn.1005-6521.2014.22.09
[19]	PAN X, WU S, YAN Y, et al. Rice bran polysaccharide-metal complexes showed safe antioxidant activity in vitro[J]. Int J Biol Macromol,2019,126:934−940. doi: 10.1016/j.ijbiomac.2018.12.265
[20]	DE MENEZES E W, GIUNTINI E B, DAN M C, et al. Codex dietary fibre definition-Justification for inclusion of carbohydrates from 3 to 9 degrees of polymerisation[J]. Food Chem,2013,140(3):581−585.
[21]	丁晓萌, 侯坤友, 胡晓祎, 等. 脱脂米糠可溶性膳食纤维对小肠葡萄糖吸收和转运的影响及其作用机制[J]. 食品科学,2020,41(1):183−189. [DING X M, HOU K Y, HU X Y, et al. Effect of soluble dietary fiber from defatted rice bran on glucose absorption and transport in small intestine and its mechanism of action[J]. Food Science,2020,41(1):183−189. doi: 10.7506/spkx1002-6630-20190606-061 DING X M, HOU K Y, HU X Y, et al. Effect of soluble dietary fiber from defatted rice bran on glucose absorption and transport in small intestine and its Mechanism of Action[J]. Food Science, 2020, 41(1), 183-189. doi: 10.7506/spkx1002-6630-20190606-061
[22]	CHOI Y S, KIM H W, HWANG K E, et al. Effects of fat levels and rice bran fiber on the chemical, textural, and sensory properties of frankfurters[J]. Food Science and Biotechnology,2015,24(2):489−495. doi: 10.1007/s10068-015-0064-5
[23]	PHIMOLSIRIPOL Y, MUKPRASIRT A, SCHOENLECHNER R. Quality improvement of rice-based gluten-free bread using different dietary fibre fractions of rice bran[J]. Journal of Cereal Science,2012,56(2):389−395. doi: 10.1016/j.jcs.2012.06.001
[24]	徐田辉, 苏玉, 黄亮, 等. 蒸汽爆破-超微粉碎米糠膳食纤维对2型糖尿病小鼠的降血糖作用[J]. 中国粮油学报,2020,35(10):9−15. [XU T H, SU Y, HUANG L, et al. Hypoglycemic effect of steam explosion-superfine pulverization rice bran dietary fiber on type 2 diabetic mice[J]. Journal of the Chinese Cereals and Oils Association,2020,35(10):9−15. doi: 10.3969/j.issn.1003-0174.2020.10.003 XU T H, SU Y, HUANG L, et al. Hypoglycemic effect of steam explosion-superfine pulverization rice bran dietary fiber on type 2 diabetic mice[J]. Journal of the Chinese Cereals and Oils Association, 2020, 35(10), 9-15. doi: 10.3969/j.issn.1003-0174.2020.10.003
[25]	黄萍, 林亲录, 朱凤霞, 等. 米糠水溶性膳食纤维理化特性及抗氧化性[J]. 食品科学,2017,38(23):14−19. [HUANG P, LIN Q L, ZHU F X, et al. Physicochemical properties and antioxidant activity of water-soluble dietary fiber from rice bran[J]. Food Science,2017,38(23):14−19. doi: 10.7506/spkx1002-6630-201723003 HUANG P, LIN Q L, ZHU F X, et al. Physicochemical properties and antioxidant activity of water-soluble dietary fiber from rice bran[J]. Food Science, 2017, 38(23), 14-19. doi: 10.7506/spkx1002-6630-201723003
[26]	LIU B, LIN Q, YANG T, et al. Oat beta-glucan ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice[J]. Food Funct,2015,6(11):3454−3463. doi: 10.1039/C5FO00563A
[27]	曹龙奎, 康丽君, 寇芳, 等. 改性前后小米糠膳食纤维结构分析及体外抑制α-葡萄糖苷酶活性[J]. 食品科学,2018,39(11):46−52. [CAO L K, KANG L J, KOU F, et al. Structural analysis and in vitro inhibitory effect on α-glucosidase activity of millet bran dietary fiber before and after modification[J]. Food Science,2018,39(11):46−52. doi: 10.7506/spkx1002-6630-201811008 CAO L K, KANG L J, KOU F, et al. Structural analysis and in vitro inhibitory effect on a-glucosidase activity of millet bran dietary fiber before and after modification[J]. Food Science, 2018, 39(11), 46-52. doi: 10.7506/spkx1002-6630-201811008
[28]	STREPPEL M T, OCKE M C, BOSHUIZEN H C, et al. Dietary fiber intake in relation to coronary heart disease and all-cause mortality over 40 y: The zutphen study[J]. Am J Clin Nutr,2008,88(4):1119−1125. doi: 10.1093/ajcn/88.4.1119
[29]	PARK Y, BRINTON L A, SUBAR A F, et al. Dietary fiber intake and risk of breast cancer in postmenopausal women: The National Institutes of health-AARP diet and health study[J]. Am J Clin Nutr,2009,90(3):664−671. doi: 10.3945/ajcn.2009.27758
[30]	TUCKER L A, THOMAS K S. Increasing total fiber intake reduces risk of weight and fat gains in women[J]. J Nutr,2009,139(3):576−581. doi: 10.3945/jn.108.096685
[31]	BELALCAZAR L M, ANDERSON A M, LANG W, et al. Fiber intake and plasminogen activator inhibitor-1 in type 2 diabetes: Look AHEAD (Action for Health in Diabetes) trial findings at baseline and year 1[J]. Journal of the Academy of Nutrition and Dietetics,2014,114(11):1800−1810, e1802.
[32]	MASANORI WATANABE C Y, ISAMU MAEDA, CHARINTECHAPUN, et al. Evaluating of quality of rice bran protein concentrate prepared by a combination of isoelectronic precipitation and electrolyzed water treatment[J]. LWT-Food Sci Technol,2019,99:262−267. doi: 10.1016/j.lwt.2018.09.059
[33]	HAN S W, CHEE K M, CHO S J. Nutritional quality of rice bran protein in comparison to animal and vegetable protein[J]. Food Chem,2015,172:766−769. doi: 10.1016/j.foodchem.2014.09.127
[34]	PRAKASH J, RAMANATHAM G. Effect of stabilisation treatment of rice bran on nutritional quality of protein concentrates[J]. International Journal of Food Sciences and Nutrition,1995,46(2):177−184. doi: 10.3109/09637489509012547
[35]	HAMADA J S. Characterization and functional properties of rice bran proteins modified by commercial exoproteases and endoproteases[J]. J Food Sci,2000,65(2):305−310. doi: 10.1111/j.1365-2621.2000.tb15998.x
[36]	WANG T, ZHANG H, WANG L, et al. Mechanistic insights into solubilization of rice protein isolates by freeze-milling combined with alkali pretreatment[J]. Food Chem,2015,178:82−88. doi: 10.1016/j.foodchem.2015.01.057
[37]	康艳玲, 王章存. 米糠蛋白研究现状[J]. 粮食与油脂,2006,3:22−24. [KANG Y L, WANG Z C. Research status of rice bran protein[J]. Cereals & Oils,2006,3:22−24. doi: 10.3969/j.issn.1008-9578.2006.02.007 KANG Y L, WANG Z C. Research status of rice bran protein[J]. Cereals & Oils, 2006, 3, 22-24. doi: 10.3969/j.issn.1008-9578.2006.02.007
[38]	于雷, 张薇, 乔筱童, 等. 超声波辅助双酶法与碱法提取米糠蛋白功能特性的比较研究[J]. 食品科技,2014,39(11):256−261. [YU L, ZHANG W, QIAO X T, et al. Comparing research on functionality of rice bran protein extracted by alkali and ultrasonic-assisted dual-enzyme[J]. Food Science and Technology,2014,39(11):256−261. YU L, ZHANG W, QIAO X T, et al. Comparing research on functionality of rice bran protein extracted by alkali and ultrasonic-assisted dual-enzyme[J]. Food Science and Technology, 2014, 39(11), 256-261.
[39]	吕飞, 许宙, 程云辉. 米糠蛋白提取及其应用研究进展[J]. 食品与机械,2014,30(3):234−238. [LÜ F, XU Z, CHENG Y H. Progress on extraction and application of rice bran protein[J]. Food & Machinery,2014,30(3):234−238. LV F, XU Z, CHENG Y H. Progress on extraction and application of rice bran protein[J]. Food & Machinery, 2014, 30(3), 234-238.
[40]	张薇. 超声波辅助双酶法提取米糠蛋白及其应用的研究[D]. 吉林: 吉林农业大学, 2014, 1−60. ZHANG W. Extraction and application of rice bran protein by ultrasonic-assisted dual-enzymatic[D]. Jilin: Jilin Agricultural University, 2014: 1−60.
[41]	侯晓丽, 孙铭学, 高焕焕, 等. 抗炎天然产物活性成分研究进展[J]. 药学实践杂志,2015,33(1):20−27. [HOU X L, SUN M X, GAO H H, et al. Progress on anti-inflammatory natural products[J]. Journal of Pharmaceutical Practice,2015,33(1):20−27. doi: 10.3969/j.issn.1006-0111.2015.01.006 HOU X L, SUN M X, GAO H H, et al. Progress on anti-inflammatory natural products[J]. Journal of Pharmaceutical Practice, 2015, 33(1), 20-27. doi: 10.3969/j.issn.1006-0111.2015.01.006
[42]	IBITOYE O B, AJIBOYE T O. Ferulic acid potentiates the antibacterial activity of quinolone-based antibiotics against Acinetobacter baumannii[J]. Microb Pathog,2019,126:393−398. doi: 10.1016/j.micpath.2018.11.033
[43]	CHEN H, NIU H, ZHANG H, et al. Preparation and properties of ferulic acid-sugar beet pulp pectin ester and its application as a physical and antioxidative stabilizer in a fish oil-water emulsion[J]. Int J Biol Macromol,2019,139:290−297. doi: 10.1016/j.ijbiomac.2019.07.222
[44]	MASUDA T, MIZUGUCHI S, TANAKA T, et al. Isolation and structure determination of new antioxidative ferulic acid glucoside esters from the rhizome of alpinia speciosa, a zingiberaceae plant used in okinawan food culture[J]. J Agric Food Chem,2000,48(5):1479−1484. doi: 10.1021/jf991294e
[45]	OU J, SUN Z. Feruloylated oligosaccharides: Structure, metabolism and function[J]. Journal of Functional Foods,2014,7:90−100. doi: 10.1016/j.jff.2013.09.028
[46]	SARAVANAN SUBRAMANI G N, GATTAMANENI LAKSHMI NARAYANA RAO. High free fatty acid crude rice bran oil–A renewable feedstock for sustainable energy and environment[J]. Clean Soil Air Water,2008,36(11):835−839.
[47]	LIU Y Q, STRAPPE P, SHANG W T, et al. Functional peptides derived from rice bran proteins[J]. Crit Rev Food Sci Nutr,2019,59(2):349−356. doi: 10.1080/10408398.2017.1374923
[48]	PHONGTHAI S, D'AMICO S, SCHOENLECHNER R, et al. Fractionation and antioxidant properties of rice bran protein hydrolysates stimulated by in vitro gastrointestinal digestion[J]. Food Chem,2018,240:156−164. doi: 10.1016/j.foodchem.2017.07.080
[49]	OGAWA Y, SHOBAKO N, FUKUHARA I, et al. Rice bran supplement containing a functional substance, the novel peptide Leu-Arg-Ala, has anti-hypertensive effects: A double-blind, randomized, placebo-controlled study[J]. Nutrients,2019,11(4):726. doi: 10.3390/nu11040726
[50]	TANIGUCHI M, SAITO K, AIDA R, et al. Wound healing activity and mechanism of action of antimicrobial and lipopolysaccharide-neutralizing peptides from enzymatic hydrolysates of rice bran proteins[J]. Journal of Bioscience and Bioengineering,2019,128(2):142−148. doi: 10.1016/j.jbiosc.2019.02.002
[51]	SAMUCHAYA NGAMSUK, JUE-LIANG HSU, TZOU-CHI HUANG, et al. Ultrasonication of milky stage rice milk with bioactive peptides from rice bran: Its bioactivities and absorption[J]. Food and Bioprocess Technology,2020,13(7):462−474.
[52]	徐浩. 米糠资源研究与应用[D]. 安徽: 安徽农业大学, 2015, 1−64. XU H. The research and application of rice bran[D]. Anhui: Anhui Agricultural University, 2015, 1−64.
[53]	CARLA BEATRIZ DE SOUZA, GIUSEPPINA PACE PEREIRA LIMA, CRISTINE VANZ BORGES, et al. Development of a functional rice bran cookie rich in γ-oryzanol[J]. Journal of Food Measurement and Characterization,2019,13(2):1070−1077. doi: 10.1007/s11694-018-00022-2
[54]	武家琪, 肇立春, 张俊杰, et al. 提高米糠油中谷维素含量的脱酸工艺研究[J]. 中国油脂,2020,45(5):27−31. [WU J Q, ZHAO L C, ZHANG J J, et al. Deacidification process to increase oryzanol content in rice bran oil[J]. China Oils and Fats,2020,45(5):27−31. doi: 10.12166/j.zgyz.1003-7969/2020.05.006 WU J Q, ZHAO L C, ZHANG J J, et al. Deacidification process to increase oryzanol content in rice bran oil[J]. China Oils and Fats, 2020, 45(5), 27-31. doi: 10.12166/j.zgyz.1003-7969/2020.05.006
[55]	MINATEL I O, FRANCISQUETI F V, CORREA C R, et al. Antioxidant activity of gamma-oryzanol: A complex network of interactions[J]. International Journal of Molecular Sciences,2016,17(8):1107. doi: 10.3390/ijms17081107
[56]	SON M J, RICO C W, NAM S H, et al. Effect of oryzanol and ferulic acid on the glucose metabolism of mice fed with a high-fat diet[J]. J Food Sci,2011,76(1):H7−H10. doi: 10.1111/j.1750-3841.2010.01907.x
[57]	钟金锋, 覃小丽, 刘雄. 凝胶油及其在食品工业中的应用研究进展[J]. 食品科学,2015,36(3):272−279. [ZHAONG J F, QIN X L, LIU X. Advances in oleogels and their applications in food industry[J]. Food Science,2015,36(3):272−279. doi: 10.7506/spkx1002-6630-201503051 ZHAONG J F, QIN X L, LIU X. Advances in oleogels and their applications in food industry[J]. Food Science, 2015, 36(3), 272-279. doi: 10.7506/spkx1002-6630-201503051
[58]	HUANG Z, GUO B, DENG C, et al. Stabilization of peanut butter by rice bran wax[J]. J Food Sci,2020,85(6):1793−1798. doi: 10.1111/1750-3841.15176
[59]	刘怡真, 马传国, 李婕妤. 不同凝胶剂对芝麻酱稳定性的影响[J]. 食品科学,2019,40(12):70−77. [LIU Y Z, MA C G, LI J Y. Effect of different organogelators on the stability of sesame paste[J]. Food Science,2019,40(12):70−77. doi: 10.7506/spkx1002-6630-20180705-066 LIU Y Z, MA C G, LI J Y. Effect of different organogelators on the stability of sesame paste[J]. Food Science, 2019, 40(12), 70-77. doi: 10.7506/spkx1002-6630-20180705-066
[60]	ZHAO M, LAN Y, CUI L, et al. Formation, characterization, and potential food application of rice bran wax oleogels: Expeller-pressed corn germ oil versus refined corn oil[J]. Food Chem,2020,309:125704. doi: 10.1016/j.foodchem.2019.125704
[61]	SAWANYA PANDOLSOOK, KUPONGSAK S. Potential use of policosanol extract from Thai bleached rice bran wax as an organogelator[J]. Journal of Food Measurement and Characterization,2020,14:2078−2086. doi: 10.1007/s11694-020-00455-8
[62]	SHIN H Y, KIM S M, LEE J H, et al. Solid-state fermentation of black rice bran with Aspergillus awamori and Aspergillus oryzae: Effects on phenolic acid composition and antioxidant activity of bran extracts[J]. Food Chem,2019,272:235−241. doi: 10.1016/j.foodchem.2018.07.174
[63]	GHASEMZADEH A, KARBALAII M T, JAAFAR H Z E, et al. Phytochemical constituents, antioxidant activity, and antiproliferative properties of black, red, and brown rice bran[J]. Chemistry Central journal,2018,12(1):17. doi: 10.1186/s13065-018-0382-9
[64]	SAJI N, FRANCIS N, BLANCHARD C L, et al. Rice bran phenolic compounds regulate genes associated with antioxidant and anti-inflammatory activity in human umbilical vein endothelial cells with induced oxidative stress[J]. International Journal of Molecular Sciences,2019,20(19):4715. doi: 10.3390/ijms20194715
[65]	NORHAIZAN M E, NG S K, NORASHAREENA M S, et al. Antioxidant and cytotoxicity effect of rice bran phytic acid as an anticancer agent on ovarian, breast and liver cancer cell lines[J]. Malays J Nutr,2011,17(3):367−375.
[66]	KELLY T, YANG W, CHEN C S, et al. Global burden of obesity in 2005 and projections to 2030[J]. Int J Obes (Lond),2008,32(9):1431−1437. doi: 10.1038/ijo.2008.102
[67]	YANG S C, HUANG W C, NG X E, et al. Rice bran reduces weight gain and modulates lipid metabolism in rats with high-energy-diet-induced obesity[J]. Nutrients,2019,11(9):2033. doi: 10.3390/nu11092033
[68]	SALAR A, FAGHIH S, PISHDAD G R. Rice bran oil and canola oil improve blood lipids compared to sunflower oil in women with type 2 diabetes: A randomized, single-blind, controlled trial[J]. J Clin Lipidol,2016,10(2):299−305. doi: 10.1016/j.jacl.2015.11.016
[69]	BUMRUNGPERT A, CHONGSUWAT R, PHOSAT C, et al. Rice bran oil containing gamma-oryzanol improves lipid profiles and antioxidant status in hyperlipidemic subjects: A randomized double-blind controlled trial[J]. Journal of Alternative and Complementary Medicine,2019,25(3):353−358. doi: 10.1089/acm.2018.0212
[70]	NIE Y, LUO F, WANG L, et al. Anti-hyperlipidemic effect of rice bran polysaccharide and its potential mechanism in high-fat diet mice[J]. Food Funct,2017,8(11):4028−4041. doi: 10.1039/C7FO00654C
[71]	LIU Q, ZHAO J, LIU S, et al. Positive intervention of insoluble dietary fiber from defatted rice bran on hyperlipidemia in high fat diet fed rats[J]. J Food Sci,2021,86:3964−3974. doi: 10.1111/1750-3841.15812
[72]	BOONLOH K, LEE E S, KIM H M, et al. Rice bran protein hydrolysates attenuate diabetic nephropathy in diabetic animal model[J]. Eur J Nutr,2018,57(2):761−772. doi: 10.1007/s00394-016-1366-y
[73]	POSUWAN J, PRANGTHIP P, LEARDKAMOLKARN V, et al. Long-term supplementation of high pigmented rice bran oil (Oryza sativa L.) on amelioration of oxidative stress and histological changes in streptozotocin-induced diabetic rats fed a high fat diet; Riceberry bran oil[J]. Food Chem,2013,138(1):501−508. doi: 10.1016/j.foodchem.2012.09.144
[74]	SIDDIQUI S, RASHID KHAN M, SIDDIQUI W A. Comparative hypoglycemic and nephroprotective effects of tocotrienol rich fraction (TRF) from palm oil and rice bran oil against hyperglycemia induced nephropathy in type 1 diabetic rats[J]. Chemico-biological Interactions,2010,188(3):651−658. doi: 10.1016/j.cbi.2010.08.010
[75]	KIM S M, RICO C W, LEE S C, et al. Modulatory effect of rice bran and phytic acid on glucose metabolism in high fat-fed C57BL/6N mice[J]. J Clin Biochem Nutr,2010,47(1):12−17. doi: 10.3164/jcbn.09-124
[76]	KANNAN A, HETTIARACHCHY N S, LAY J O, et al. Human cancer cell proliferation inhibition by a pentapeptide isolated and characterized from rice bran[J]. Peptides,2010,31(9):1629−1634. doi: 10.1016/j.peptides.2010.05.018
[77]	AL-FATLAWI A A, AL-FATLAWI A A, IRSHAD M, et al. Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells[J]. Asian Pac J Cancer Prev,2014,15(8):3731−3736. doi: 10.7314/APJCP.2014.15.8.3731
[78]	SAAD N, ESA N M, ITHNIN H. Suppression of beta-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA)[J]. Asian Pac J Cancer Prev,2013,14(5):3093−3099. doi: 10.7314/APJCP.2013.14.5.3093
[79]	SOMINTARA S, LEARDKAMOLKARN V, SUTTIARPORN P, et al. Anti-tumor and immune enhancing activities of rice bran gramisterol on acute myelogenous leukemia[J]. PLoS One,2016,11(1):e0146869. doi: 10.1371/journal.pone.0146869
[80]	姜元荣, 姚惠源, 陈正行. 米糠粗多糖对小鼠免疫调节功能影响研究[J]. 粮食与油脂,2004(5):20−23. [JIANG Y R, YAO H Y, CHEN Z X. Investigation on immunomodulating activities of rice bran polysaccharides in mice[J]. Cereals & Oils,2004(5):20−23. doi: 10.3969/j.issn.1008-9578.2004.01.006 JIANG Y R, YAO H Y, CHEN Z X. Investigation on immunomodulating activities of rice bran polysaccharides in mice[J]. Cereals & Oils, 2004, 05, 20-23. doi: 10.3969/j.issn.1008-9578.2004.01.006
[81]	SHIN S Y, KIM H W, JANG H H, et al. Gamma-oryzanol-rich black rice bran extract enhances the innate immune response[J]. Journal of Medicinal Food,2017,20(9):855−863. doi: 10.1089/jmf.2017.3966
[82]	KIM S P, PARK S O, LEE S J, et al. A Polysaccharide isolated from the liquid culture of Lentinus edodes (Shiitake) mushroom mycelia containing black rice bran protects mice against salmonellosis through upregulation of the Th1 immune reaction[J]. Journal of Agricultural and Food Chemistry,2014,62(11):2384−2391. doi: 10.1021/jf405223q
[83]	ISHAKA A, IMAM M U, ISMAIL M. Nanoemulsification of rice bran wax policosanol enhances its cardio-protective effects via modulation of hepatic peroxisome proliferator-activated receptor gamma in hyperlipidemic rats[J]. J Oleo Sci,2020,69(10):1287−1295. doi: 10.5650/jos.ess20098
[84]	CHENG C Y, HO T Y, LEE E J, et al. Ferulic acid reduces cerebral infarct through its antioxidative and anti-inflammatory effects following transient focal cerebral ischemia in rats[J]. Am J Chin Med,2008,36(6):1105−1119. doi: 10.1142/S0192415X08006570
[85]	WANG L, LI Y, ZHU L, et al. Antitumor activities and immunomodulatory of rice bran polysaccharides and its sulfates in vitro[J]. Int J Biol Macromol,2016,88:424−432. doi: 10.1016/j.ijbiomac.2016.04.016

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Research Progress on Functional Active Components and Its Efficacy in Rice Bran