Simultaneous Determination of 22 Phthalate Esters in Milk Powder by GC-MS/MS

WANG Jincui; WANG Xirui

doi:10.13386/j.issn1002-0306.2021060214

Volume 43 Issue 5

Feb. 2022

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Science and Technology of Food Industry > 2022 > 43(5): 280-285. > DOI: 10.13386/j.issn1002-0306.2021060214

WANG Jincui, WANG Xirui. Simultaneous Determination of 22 Phthalate Esters in Milk Powder by GC-MS/MS[J]. Science and Technology of Food Industry, 2022, 43(5): 280−285. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021060214.

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Simultaneous Determination of 22 Phthalate Esters in Milk Powder by GC-MS/MS

WANG Jincui^1,,
WANG Xirui²

1.
Heilongjiang Province Tianrun Inspection and Research Institute Co., Ltd., Harbin 150009, China
2.
Heilongjiang Provincial Center for Drug Inspection, Harbin 150001, China

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Received Date: June 23, 2021
Available Online: January 04, 2022

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Abstract

Abstract

A suitable GC-MS/MS method was established for the determination of 22 phthalate esters (PAEs) in milk powder. The milk powder samples were dissolved in water, extracted by acetonitrile, salted out by NaCl, then quantitated by GC-MS/MS in multiple reaction monitoring mode (MRM). As a result, 22 PAEs possessed an excellent linear relation by using matrix-matched standard curve under 5~500 ng/mL, the correlation coefficients were all greater than 0.99, LODwas 1.0~5.0 μg/kg, LOQ was 3.0~15.0 μg/kg. The recoveries were 82.4%~111.4% at three spiked level with relative standard deviation (n=6) of 2.4%~9.5%. This analytical method is simple, quick, sensitive and stable, which can be used for a monitoring and screening analysis of 22 PAEs in milk powder.
- gas chromatography tandem triple quadruple mass spectrometry (GC-MS/MS),
- phthalate esters,
- milk powder

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References

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