CHEN Lihua, SHAN Yahui, GUAN Yongmei, et al. Research Progress on the Effect of Medicinal and Edible Substances on Improving Gastrointestinal Tract Function[J]. Science and Technology of Food Industry, 2023, 44(4): 480−487. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022040318.
Citation: CHEN Lihua, SHAN Yahui, GUAN Yongmei, et al. Research Progress on the Effect of Medicinal and Edible Substances on Improving Gastrointestinal Tract Function[J]. Science and Technology of Food Industry, 2023, 44(4): 480−487. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022040318.

Research Progress on the Effect of Medicinal and Edible Substances on Improving Gastrointestinal Tract Function

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  • Received Date: April 17, 2022
  • Available Online: November 30, 2022
  • Gastrointestinal dysfunction can cause a few chronic diseases or other health problems. Maintaining the health of the gastrointestinal tract is essential to improve human health and quality of life. Medicinal and edible substances as main raw materials have shown greater benefits in improving gastrointestinal tract function. This paper summarizes the medicinal and edible substances and ancient prescriptions containing medicinal and edible substances, and analyzes the mechanism of medicinal and edible substances and compound prescriptions for improving gastrointestinal tract function from three aspects: Anti-Helicobacter pylori, digestion promotion and gastric mucosa protection. Finally, we analyze the efficacy and formulae of existing food products for improving gastrointestinal tract on the market, in order to provide some ideas for further development of dietary resources and research of dietary therapy products with improving gastrointestinal tract functions.
  • [1]
    WANG T, LIU K, WEN L, et al. Autophagy and gastrointestinal diseases[J]. Advances in Experimental Medicine and Biology,2020,1207:529−556.
    [2]
    郭思嘉, 姜东京, 李振岚, 等. 肠道菌群与常见胃肠道疾病关系及中药与微生态制剂治疗方法的研究进展[J]. 中草药,2018,49(18):4424−4431. [GUO S J, JIANG D J, LI Z L, et al. Research progress on the relationship between intestinal flora and common gastrointestinal diseases and the treatment methods of traditional Chinese medicine and microecological agents[J]. Chinese Herbal Medicine,2018,49(18):4424−4431. doi: 10.7501/j.issn.0253-2670.2018.18.030
    [3]
    WAUTERS L, TALLEY N J, WALKER M M, et al. Novel concepts in the pathophysiology and treatment of functional dyspepsia[J]. Gut,2020,69(3):591−600. doi: 10.1136/gutjnl-2019-318536
    [4]
    PANARELLI N C, YANTISS R K. Inflammatory and infectious manifestations of immunodeficiency in the gastrointestinal tract[J]. Modern Pathology,2018,31(6):844−861. doi: 10.1038/s41379-018-0015-9
    [5]
    HILLS R D, PONTEFRACT B A, MISHCON H R, et al. Gut microbiome: Profound implications for diet and disease[J]. Nutrients,2019,11(7):1613. doi: 10.3390/nu11071613
    [6]
    XU J, J ZHANG J, SANG Y, et al. Polysaccharides from medicine and food homology materials: A review on their extraction, purification, structure, and biological activities[J]. Molecules,2022,27(10):3215. doi: 10.3390/molecules27103215
    [7]
    XUE Z W, CAO Z, JIN M, et al. New steroid saponins from yam and their medicinal use against I/R anti-inflammatory effect[J]. Food & Function,2021,12(18):8314−8325.
    [8]
    LU Q, LI R, YANG Y, et al. Ingredients with anti-inflammatory effect from medicine food homology plants[J]. Food Chemistry,2022,368:130610. doi: 10.1016/j.foodchem.2021.130610
    [9]
    XIA X, XIAO J. Natural Ingredients from medicine food homology as chemopreventive reagents against Type 2 diabetes mellitus by modulating gut microbiota homoeostasis[J]. Molecules,2021,26(22).
    [10]
    贾铭杰, 骆嘉原, 蒋士龙, 等. 植物活性成分抗骨质疏松症的研究进展[J]. 食品工业科技,2022,43(16):400−412. [JIA M J, LUO J Y, JIANG S L, et al. Research progress of plant active ingredients in anti osteoporosis[J]. Science and Technology of Food Industry,2022,43(16):400−412.
    [11]
    赵鹏葳, 简敬一, 任孟月. 药食同源中药治疗肥胖症的有效成分和机制研究进展[J]. 广东药科大学学报,2021,37(3):141−149. [ZHAO P W, JIAN J Y, REN M Y. Research progress on the effective components and mechanism of Chinese herbal medicine and food homology in the treatment of obesity[J]. Journal of Guangdong Pharmaceutical University,2021,37(3):141−149.
    [12]
    仲丽丽, 路鑫, 赵秦妍, 等. “药食同源”药材及其有效成分对阿尔茨海默病的作用及机制的研究进展[J]. 中国实验方剂学杂志,2022,28(21):235−242. [ZHONG L L, LU X, ZHAO Q Y, et al. Research progress on the effect and mechanism of ''drug and food homologous'' medicinal materials and their effective components on Alzheimer's disease[J]. Chinese Journal of Experimental Formulary,2022,28(21):235−242.
    [13]
    宋向飞, 雷雅坤, 刘宁, 等. 药食同源花叶类植物对高尿酸血症的功效及机理研究进展[J]. 华北农学报,2021,36(S1):195−201. [SONG X F, LEI Y K, LIU N, et al. Research progress on the efficacy and mechanism of medicinal and edible homologous mosaic plants on hyperuricemia[J]. North China Agricultural Journal,2021,36(S1):195−201. doi: 10.7668/hbnxb.2019261602
    [14]
    陈姣, 游宇, 廖婉, 等. 药食同源中药青果的保健功效及现代应用探析[J]. 中草药,2021,52(20):6442−6454. [CHEN J, YOU Y, LIAO W, et al. Analysis on the health care efficacy and modern application of Chinese herbal medicine fruits with the same origin as medicine and food[J]. Chinese Herbal Medicine,2021,52(20):6442−6454. doi: 10.7501/j.issn.0253-2670.2021.20.035
    [15]
    SONG D X, JIANG J G. Hypolipidemic components from medicine food homology species used in China: Pharmacological and health effects[J]. Archives of Medical Research,2017,48(7):569−581. doi: 10.1016/j.arcmed.2018.01.004
    [16]
    刘又嘉, 龙承星, 贺璐, 等. 四君茶与猴头菇健脾养胃的研究进展[J]. 中国微生态学杂志,2017,29(4):487−493. [LIU Y J, LONG C X, HE L, et al. Research progress of Sijun tea and Hericium erinaceus in invigorating spleen and stomach[J]. Chinese Journal of Microbiology,2017,29(4):487−493.
    [17]
    黄丹旋, 黎焕杰, 陈珏璇, 等. 健脾养胃膏方治疗气虚质慢性疲劳综合征临床观察[J]. 中华中医药杂志,2020,35(12):6440−6443. [HUANG D X, LI H J, CHEN Y X, et al. Clinical observation of Jianpi Yangwei ointment in the treatment of chronic fatigue syndrome due to Qi deficiency[J]. Chinese Journal of traditional Chinese medicine,2020,35(12):6440−6443.
    [18]
    CHIEN M Y, LIN Y T, PENG F C, et al. Gastroprotective potential against indomethacin and safety assessment of the homology of medicine and food formula cuttlebone complex[J]. Food & function,2015,6(8):2803−2812.
    [19]
    唐雪阳, 谢果珍, 周融融, 等. 药食同源的发展与应用概况[J]. 中国现代中药,2020,22(9):1428−1433. [TANG X Y, XIE G Z, ZHOU R R, et al. Development and application of drug food homology[J]. Chinese Modern Traditional Chinese Medicine,2020,22(9):1428−1433.
    [20]
    严姝霞, 陈仁寿, 徐桂华, 等. 药食两用性药(食)物性效与病症宜忌探析[J]. 护理研究,2016,30(30):3790−3792. [YAN S X, CHEN R S, XU G H, et al. Analysis on the physical properties and effects of dual-purpose drugs (food) and diseases[J]. Nursing Research,2016,30(30):3790−3792.
    [21]
    杨亚湉, 王瑞, 钱程程, 等. 乌梅化学成分、药理作用研究进展及质量标志物预测[J/OL]. 中成药: 1−7 [2022-06-26]. http://www.cnki.com.cn/Article/CJFDTotal-ZCYA20220325003.htm.

    YANG Y T, WANG R, QIAN C C, et al. Research progress on chemical constituents, pharmacological effects and prediction of quality markers of black plum [J/OL] Chinese Patent Medicine: 1−7 [2022-04-18]. http://www.cnki.com.cn/Article/CJFDTotal-ZCYA20220325003.htm.
    [22]
    乔宏萍, 武晓英, 燕平梅, 等. 药食两用植物对幽门螺杆菌的抑菌活性测定[J]. 首都食品与医药,2016,23(6):74−75. [QIAO H P, WU X Y, YAN P M, et al. Determination of antimicrobial activity of medicinal and edible plants against Helicobacter pylori[J]. Capital Food and Medicine,2016,23(6):74−75.
    [23]
    孙俊波, 赵璐, 史素琴, 等. 甘草次酸抑制胃溃疡大鼠胃黏膜细胞的凋亡[J]. 中成药,2017,39(3):462−466. [SUN J B, ZHAO L, SHI S Q, et al. Glycyrrhetinic acid inhibits apoptosis of gastric mucosal cells in rats with gastric ulcer[J]. Chinese Patent Medicine,2017,39(3):462−466. doi: 10.3969/j.issn.1001-1528.2017.03.004
    [24]
    CAO D, JIANG J, YOU L, et al. The protective effects of 18β-glycyrrhetinic acid on helicobacter pylori-infected gastric mucosa in Mongolian gerbils[J]. BioMed Research International,2016,2016:1−8.
    [25]
    董嘉琪, 陈金鹏, 龚苏晓, 等. 山楂的化学成分、药理作用及质量标志物(Q-Marker)预测[J]. 中草药,2021,52(9):2801−2818. [DONG J Q, CHEN J P, GONG S X, et al. Chemical composition, pharmacological action and quality marker prediction of Hawthorn[J]. Chinese Herbal Medicine,2021,52(9):2801−2818.
    [26]
    封若雨, 朱新宇, 张苗苗. 近五年山楂药理作用研究进展[J]. 中国中医基础医学杂志,2019,25(5):715−718. [FENG R Y, ZHU X Y, ZHANG M M. Research progress on pharmacological action of Hawthorn in recent five years[J]. Chinese Journal of Basic Medicine of Traditional Chinese Medicine,2019,25(5):715−718.
    [27]
    辛卫云, 白明, 苗明三. 麦芽的现代研究[J]. 中医学报,2017,32(4):613−615. [XIN W Y, BAI M, MIAO M S. Modern research on malt[J]. Journal of Traditional Chinese Medicine,2017,32(4):613−615.
    [28]
    杨延超. 大麦芽活性多糖的分离及结构解析[D]. 无锡: 江南大学, 2012

    YANG Y C. Isolation and structural analysis of active polysaccharides from malt [D]. Wuxi: Jiangnan University, 2012.
    [29]
    龙超君, 白辰, 黄羚, 等. 基于网络药理学方法探讨莱菔子对胃肠动力的影响机制[J]. 中国中医药信息杂志,2020,27(12):83−90. [LONG C J, BAI C, HUANG L, et al. Study on the influence mechanism of semen Raphani on gastrointestinal motility based on network pharmacology[J]. Chinese Journal of Traditional Chinese Medicine Information,2020,27(12):83−90.
    [30]
    沈明, 黄小强, 阮美江. 鸡内金对功能性消化不良模型大鼠胃肠功能改善作用[J]. 福建中医药,2019,50(4):35−37. [SHEN M, HUANG X Q, RUAN M J. Effect of Jineijin on gastrointestinal function in rats with functional dyspepsia[J]. Fujian Traditional Chinese Medicine,2019,50(4):35−37. doi: 10.3969/j.issn.1000-338X.2019.04.013
    [31]
    迟玉森, 马成印, 邵允琪, 等. 鸡内金有效成分的提取及其改善肠道保健功能的研究[J]. 食品工业科技,1999(4):23−24. [CHI Y S, MA C Y, SHAO Y Q, et al. Study on the extraction of effective components from Radix et Rhizoma henryi and its improvement of intestinal health care function[J]. Science and Technology of Food Industry ,1999(4):23−24.
    [32]
    HAN C, WANG L R, YU K Q, et al. Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori[J]. The FEBS Journal,2006,273(20):4682−4692. doi: 10.1111/j.1742-4658.2006.05469.x
    [33]
    KUNDU P, DE R, PAL I, et al. Curcumin alleviates matrix metalloproteinase-3 and -9 activities during eradication of Helicobacter pylori infection in cultured cells and mice[J]. PloS One,2011,6(1):e16306. doi: 10.1371/journal.pone.0016306
    [34]
    张南炀, 潘钰, 吴虢东, 等. 6-姜酚治疗实验性自身免疫性脑脊髓炎的免疫学机制[J]. 昆明医科大学学报,2018,39(12):23−27. [ZHANG N Y, PAN Y, WU G D, et al. Immunological mechanism of 6-gingerol in the treatment of experimental autoimmune encephalomyelitis[J]. Journal of Kunming Medical University,2018,39(12):23−27. doi: 10.3969/j.issn.1003-4706.2018.12.005
    [35]
    CHENG L, YU L, CHEN X Y, et al. Analysis of the N-glycoforms and immunoactivity of a Chinese yam (Dioscorea opposita Thunb.) glycoprotein 30CYGP[J]. Journal of Proteome Research,2020,19(1):28−35. doi: 10.1021/acs.jproteome.9b00102
    [36]
    刘宝山, 纪超伦, 杨向东, 等. 穿龙薯蓣皂苷抑制再生障碍性贫血p-mTOR/p-S6的机制研究[J]. 中国中医基础医学杂志,2014,20(12):1637−1641. [LIU B S, JI C L, YANG X D, et al. Study on the mechanism of diosgenin in inhibiting p-mTOR/P-S6 in Aplastic anemia[J]. Chinese Journal of Basic Medicine of Traditional Chinese Medicine,2014,20(12):1637−1641.
    [37]
    何灵, 史文, 代红燕, 等. 马齿苋多糖对反流性食管炎模型大鼠的保护作用及其机制研究[J]. 新疆医科大学学报,2021,44(2):174−179. [HE L, SHI W, DAI H Y, et al. Protective effect of purslane polysaccharide on reflux esophagitis model rats and its mechanism[J]. Journal of Xinjiang Medical University,2021,44(2):174−179.
    [38]
    吴国泰, 武玉鹏, 牛亭惠, 等. 蜂蜜的化学、药理及应用研究概况[J]. 蜜蜂杂志,2017,37(1):3−6. [WU G T, WU Y P, NIU T H, et al. Overview of research on chemistry, pharmacology and application of honey[J]. Bee Magazine,2017,37(1):3−6. doi: 10.3969/j.issn.1003-9139.2017.01.004
    [39]
    王倩, 别玉龙, 王豆, 等. 蒲公英多糖对溃疡性结肠炎大鼠IL-6/STAT3信号通路的影响[J]. 中国应用生理学杂志,2017,33(5):422−425. [WANG Q, BIE Y L, WANG D, et al. Effect of dandelion polysaccharide on IL-6 / STAT3 signaling pathway in rats with ulcerative colitis[J]. Chinese Journal of Applied Physiology,2017,33(5):422−425. doi: 10.12047/j.cjap.5525.2017.102
    [40]
    TALAPPHET N, PALANISAMY S, Li C, et al. Polysaccharide extracted from Taraxacum platycarpum root exerts immunomodulatory activity via MAPK and NF-κB pathways in RAW264.7 cells[J]. Journal of Ethnopharmacology,2021,281:114519. doi: 10.1016/j.jep.2021.114519
    [41]
    KIM H, KIM H W, YU K W, et al. Polysaccharides fractionated from enzyme digests of Korean red ginseng water extracts enhance the immunostimulatory activity[J]. International Journal of Biological Macromolecules,2019,121:913−920. doi: 10.1016/j.ijbiomac.2018.10.127
    [42]
    WANG S, ZHAO Y, ZHANG J Q, et al. Antidiarrheal effect of Alpinia oxyphylla Miq. (Zingiberaceae) in experimental mice and its possible mechanism of action[J]. Journal of Ethnopharmacology,2015,168:182−190. doi: 10.1016/j.jep.2015.03.066
    [43]
    房磊臣, 刘嫱, 高新征, 等. 黎药益智仁不同极性部位提取物对实验性肠炎模型小鼠的影响[J]. 中国药房,2017,28(16):2220−2223. [FANG L C, LIU Q, GAO X Z, et al. Effects of extracts from different polar parts of Liyao Yizhiren on experimental enteritis model mice[J]. China Pharmacy,2017,28(16):2220−2223. doi: 10.6039/j.issn.1001-0408.2017.16.16
    [44]
    PARAFATI M, LASCALA A, MORITTU V M, et al. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome[J]. The Journal of Nutritional Biochemistry,2015,26(9):938−948. doi: 10.1016/j.jnutbio.2015.03.008
    [45]
    李雅倩, 刘家奇, 朱晓芳, 等. 幽门螺杆菌检测技术研究进展及展望[J]. 微生物学报,2022,62(5):1645−1655. [LI Y Q, LIU J Q, ZHU X F, et al. Research progress and prospect of helicobacter pylori detection technology[J]. Journal of Microbiology,2022,62(5):1645−1655. doi: 10.13343/j.cnki.wsxb.20210640
    [46]
    TAO Z H, HAN J X, FANG J Y. Helicobacter pylori infection and eradication: Exploring their impacts on the gastrointestinal microbiota[J]. Helicobacter,2020,25(6).
    [47]
    罗佳, 金锋. 幽门螺杆菌与人类的共生进化关系[J]. 科学通报,2018,63(8):701−711. [LUO J, JIN F. Symbiotic evolutionary relationship between Helicobacter pylori and human[J]. Science Bulletin,2018,63(8):701−711.
    [48]
    LI N, XU X, YANG H, et al. Activation of aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial-mesenchymal transition via the MEK/ERK pathway[J]. Helicobacter,2021,26(5).
    [49]
    MAHADY G B, PENDLAND S L, YUN G S, et al. Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+strains of Helicobacter pylori[J]. Anticancer Research,2003,23(5A):3699.
    [50]
    HAIIAHAMOHAMMADI A A, ZARGER A, OVEISI S, et al. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori[J]. The Brazilian Journal of Infectious Diseases,2016,20(6):534−538. doi: 10.1016/j.bjid.2016.07.015
    [51]
    吕帅宜, 林开文, 邓雨婷, 等. 山奈素对小鼠乙醇型胃溃疡的影响及其机制[J]. 江苏大学学报(医学版),2021,31(6):517−521. [LÜ S Y, LIN K W, DENG Y T, et al. Effect of kaempferol on ethanol induced gastric ulcer in mice and its mechanism[J]. Journal of Jiangsu University (Medical Edition),2021,31(6):517−521.
    [52]
    LIU Y Z, SUI D Y, FU W W, et al. Protective effects of polysaccharides from Panax ginseng on acute gastric ulcers induced by ethanol in rats[J]. Food & Function,2021,12(6):2741−2749.
    [53]
    LI S S, QI Y L, CHEN L X, et al. Effects of Panax ginseng polysaccharides on the gut microbiota in mice with antibiotic-associated diarrhea[J]. International Journal of Biological Macromolecules,2019,124:931−937. doi: 10.1016/j.ijbiomac.2018.11.271
    [54]
    BAI X, FU R, DUAN Z, et al. Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice[J]. Food Research International,2021,146:110465. doi: 10.1016/j.foodres.2021.110465
    [55]
    KITAZAWA T, KAIYA H. Motilin comparative study: Structure, distribution, receptors, and gastrointestinal motility[J]. Frontiers in Endocrinology,2021,12:700884. doi: 10.3389/fendo.2021.700884
    [56]
    JIANG Z, CAO L, LIU B, et al. Effects of Chinese herbal medicine Xiangbin prescription on gastrointestinal motility[J]. World Journal of Gastroenterology,2017,23(16):2987. doi: 10.3748/wjg.v23.i16.2987
    [57]
    梁国栋, 吴启进, 娜黑芽. 沙棘糖浆对食积症模型小鼠的消食化滞作用[J]. 药学研究,2020,39(9):501−503. [LIANG G D, WU Q J, N H Y. Effect of seabuckthorn syrup on digestion and stagnation in mice with food accumulation syndrome[J]. Pharmaceutical Research,2020,39(9):501−503.
    [58]
    FAROKHNIA M, MURPHY G, WEINSTEIN S J, et al. A population-based investigation of the association between alcohol intake and serum total ghrelin concentrations among cigarette-smoking, non-alcohol-dependent male individuals[J]. Drug and Alcohol Dependence,2021,226:108835. doi: 10.1016/j.drugalcdep.2021.108835
    [59]
    WU T. Antacid effects of Chinese herbal prescriptions assessed by a modified artificial stomach model[J]. World Journal of Gastroenterology,2010,16(35):4455. doi: 10.3748/wjg.v16.i35.4455
    [60]
    SCHUBERT M L. Physiologic, pathophysiologic, and pharmacologic regulation of gastric acid secretion[J]. Current Opinion in Gastroenterology,2017,33(6):430−438. doi: 10.1097/MOG.0000000000000392
    [61]
    VON ROSENVINGE E C, RAUFMAN J P. Gastrointestinal peptides and regulation of gastric acid secretion[J]. Current Opinion in Endocrinology, Diabetes and Obesity,2010,17(1):40−43. doi: 10.1097/MED.0b013e32833304e1
    [62]
    LONG L, WANG J, CHEN N, et al. Curcumin ameliorates reserpine-induced gastrointestinal mucosal lesions through inhibiting IκB-α/NF-κB pathway and regulating expression of vasoactive intestinal peptide and gastrin in rats[J]. Journal of Medicinal Food,2016,19(6):528−534. doi: 10.1089/jmf.2015.3570
    [63]
    AZAB S S, ABDEL JALEEL G A, ELDAHSHAN O A. Anti-inflammatory and gastroprotective potential of leaf essential oil of Cinnamomum glanduliferum in ethanol-induced rat experimental gastritis[J]. Pharmaceutical Biology,2017,55(1):1654−1661. doi: 10.1080/13880209.2017.1314512
    [64]
    MEYER A R, GOLDENRING J R. Injury, repair, inflammation and metaplasia in the stomach[J]. The Journal of Physiology,2018,596(17):3861−3867. doi: 10.1113/JP275512
    [65]
    海兴华, 李华南, 张玮, 等. 基于脑-肠轴探讨腹部推拿调控神经内分泌系统促进胃黏膜损伤修复的作用机制[J]. 辽宁中医杂志,2018,45(9):1860−1862. [HAI X H, LI H N, ZHANG W, et al. To explore the mechanism of abdominal massage regulating the neuroendocrine system and promoting the repair of gastric mucosal injury based on the brain gut axis[J]. Liaoning Journal of Traditional Chinese Medicine,2018,45(9):1860−1862.
    [66]
    张婉迎, 白雪媛, 杨俊杰, 等. 铁皮石斛水溶性总蛋白对大鼠胃黏膜损伤及炎症反应的保护机制研究[J]. 食品研究与开发,2020,41(10):39−45. [ZHANG W Y, BAI X Y, YANG J J, et al. Protective mechanism of Dendrobium candidum water-soluble total protein on gastric mucosal injury and inflammatory response in rats[J]. Food Research and Development,2020,41(10):39−45.
    [67]
    CHEN W C, WU D, JIN Y L, et al. Pre-protective effect of polysaccharides purified from Hericium erinaceus against ethanol-induced gastric mucosal injury in rats[J]. International Journal of Biological Macromolecules,2020,159:948−956. doi: 10.1016/j.ijbiomac.2020.05.163
    [68]
    陈自泓, 黄可儿. 黄芪多糖对乙醇诱导的大鼠胃黏膜损伤的修复机制[J]. 广州中医药大学学报,2021,38(12):2750−2756. [CHEN Z H, HUANG K E. Repair mechanism of Astragalus polysaccharides on ethanol induced gastric mucosal injury in rats[J]. Journal of Guangzhou University of Traditional Chinese Medicine,2021,38(12):2750−2756.
    [69]
    CAI T T, ZHANG C Z, ZHAO Z M, et al. The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats[J]. Biomedicine & Pharmacotherapy=Biomedecine & Pharmacotherapie,2018,104:291−299.
    [70]
    LIN X C, CHEN Y Y, BAI S T, et al. Protective effect of licoflavone on gastric mucosa in rats with chronic superficial gastritis[J]. Journal of Southern Medical University,2013,33(2):299−304.
    [71]
    GAO J H, GUO L J, HUANG Z Y, et al. Roles of cellular polyamines in mucosal healing in the gastrointestinal tract[J]. Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society,2013,64(6):681−693.
    [72]
    赵世清, 李茹柳, 年立全, 等. 甘草对大鼠应激性溃疡及多胺影响的研究[J]. 中成药,2015,37(3):626−629. [ZHAO S Q, LI R L, NIAN L Q, et al. Effects of Glycyrrhiza uralensis on stress ulcer and polyamines in rats[J]. Chinese Patent Medicine,2015,37(3):626−629.
    [73]
    王东旭, 李茹柳, 朱易平, 等. 从多胺及细胞连接蛋白角度探讨四君子汤防治胃黏膜损伤的作用机制[J]. 中药材,2018,41(12):2886−2892. [WANG D X, LI R L, ZHU Y P, et al. To explore the mechanism of Sijunzi decoction in preventing and treating gastric mucosal injury from the perspective of polyamines and cell connexin[J]. Chinese Herbal Medicine,2018,41(12):2886−2892.
    [74]
    肖鹤松, 刘玲. 基于脑肠轴理论探讨和胃安神法治疗失眠的机制[J]. 成都中医药大学学报,2021,44(2):108−113. [XIAO H S, LIU L. Based on the theory of brain gut axis and the mechanism of stomach tranquilizing method in the treatment of insomnia[J]. Journal of Chengdu University of Traditional Chinese Medicine,2021,44(2):108−113.
    [75]
    唐惠. 中医外治治疗黄褐斑疗效及安全性的网状meta分析[D]. 武汉: 湖北中医药大学, 2021

    TANG H. Reticular meta-analysis of the efficacy and safety of external treatment of Chloasma with traditional Chinese medicine [D]. Wuhan: Hubei University of Traditional Chinese Medicine, 2021.
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