Research Progress on the Effects and Mechanisms of L-carnitine on Improving Metabolic Syndrome

SUN Chengyuan; ZHANG Yuling; CHEN Qianru; LI Jiangping; LI Tao; WEI Yuxi; GAO Xiang

doi:10.13386/j.issn1002-0306.2022030263

Volume 44 Issue 1

Dec. 2022

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Science and Technology of Food Industry > 2023 > 44(1): 475-484. > DOI: 10.13386/j.issn1002-0306.2022030263

SUN Chengyuan, ZHANG Yuling, CHEN Qianru, et al. Research Progress on the Effects and Mechanisms of L-carnitine on Improving Metabolic Syndrome[J]. Science and Technology of Food Industry, 2023, 44(1): 475−484. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022030263.

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Research Progress on the Effects and Mechanisms of L-carnitine on Improving Metabolic Syndrome

1.
College of Life Sciences, Qingdao University, Qingdao 266071, China
2.
College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
3.
Anqiu Huatao Food Co., Ltd., Weifang 262100, China

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Received Date: March 22, 2022
Available Online: November 02, 2022

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Abstract

Abstract

Metabolic syndrome is a group of clinical syndromes, including obesity, dyslipidemia, hypertension, hyperuricemia, hyperglycemia and insulin resistance. These syndromes are critical risk factors for cardiovascular disease and diabetes. Recent studies indicate that L-carnitine exhibits potential improvement effects on metabolic syndrome. In the current study, the sources of L-carnitine for human and the effects and mechanisms of L-carnitine on the major components of metabolic syndrome, such as obesity and dyslipidemia, etc were summarized. The potential health risk of L-carnitine by serving as a dietary precursor for trimethylamine N-oxide was also discussed. This study provides theoretical basis and references for the treatment of metabolic syndrome and the rational dietary supplement and utilization of L-carnitine.
- L-carnitine,
- metabolic syndrome,
- improvement effects,
- mechanisms,
- trimethylamine N-oxide

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References

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