Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity

LI Honglin; LI Yifang; ZHANG Chi; ZHOU Hongyuan; GUO Ting; ZHANG Yuhao; MA Liang

doi:10.13386/j.issn1002-0306.2021090341

Volume 43 Issue 17

Aug. 2022

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Science and Technology of Food Industry > 2022 > 43(17): 494-500. > DOI: 10.13386/j.issn1002-0306.2021090341

LI Honglin, LI Yifang, ZHANG Chi, et al. Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity[J]. Science and Technology of Food Industry, 2022, 43(17): 494−500. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021090341.

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Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity

LI Honglin^1,,
LI Yifang¹,
ZHANG Chi¹,
ZHOU Hongyuan^{1, 3},
GUO Ting^{1, 3},
ZHANG Yuhao^{1, 2, 3, 4},
MA Liang^{1, 3, 4, ,}

1.
College of Food Science, Southwest University, Chongqing 400715, China
2.
Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing 400715, China
3.
Chongqing Key Laboratory of Speciality Food Co-built by Sichuan and Chongqing, Chongqing 400715, China
4.
Key Laboratory of Condiment Supervision Technology for State Market Regulation,Chongqing 400715, China

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Received Date: September 28, 2021
Available Online: June 27, 2022

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Abstract

Abstract

To intervene and control the toxic effects of the hazard factors using nature products is one of the research hotspots recently in the field of food safety. Curcumin, as a hydrophobic polyphenolic compound extracted from the traditional spice turmeric, has strong anti-inflammatory, anti-oxidation, anti-cancer, enhancing immunity and other activities. Recent studies have shown that curcumin can intervene some toxicities induced by mycotoxins such as Aflatoxin B₁, Ochratoxin A, Zearalenone, Fumonisin B₁ and Deoxynivalenol, thereby reducing damages and enhancing resistance in body. In this paper, the toxicities of main mycotoxins were briefly summarized at first. And then, the intervention effects and its related mechanism of curcumin on the mycotoxin-induced toxicities in the latest five years were emphatically elaborated, mainly from the aspects of reducing ROS production and lipid peroxidation, regulating related pathways and improving intestinal flora. Finally, the potential problems that to be urgently solved are discussed. Our review aimed at providing the theoretical bases for the in-depth development and utilization of curcumin in the health industry as well as to broaden the ideas for the research and development of other plant-derived functional components.
- curcumin,
- mycotoxin,
- toxicity,
- intervention mechanism,
- plant-derived

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References (57)

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