Research Progress on the Production Technology and Physiological Function of D-mannose

NI Weiwei; HU Chaoqun; BAI Fulai; JI Wenna; ZHANG Qian

doi:10.13386/j.issn1002-0306.2021080363

Volume 43 Issue 17

Aug. 2022

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Science and Technology of Food Industry > 2022 > 43(17): 458-465. > DOI: 10.13386/j.issn1002-0306.2021080363

NI Weiwei, HU Chaoqun, BAI Fulai, et al. Research Progress on the Production Technology and Physiological Function of D-mannose[J]. Science and Technology of Food Industry, 2022, 43(17): 458−465. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021080363.

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Research Progress on the Production Technology and Physiological Function of D-mannose

1.
Jinan Shengquan Group Share Holding Co., Ltd., Jinan 250000, China
2.
Healtang Biotech Co., Ltd., Jinan 250000, China

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Received Date: August 30, 2021
Available Online: June 29, 2022

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Abstract

Abstract

D-mannose is the C-2 epimer of D-glucose. The production methods of D-mannose include plant extraction, chemical synthesis, and biotransformation. In particular, the biotransformation method has received more and more attention. D-mannose has been found to have a variety of important physiological functions. On the one hand, D-mannose can protect the urinary system by preventing bacteria from adhering to the urothelium. On the other hand, D-mannose can interfere with glucose metabolism, transport and modified anti-cancer drug carriers play an anti-tumor effect. In addition, D-Mannose can regulate the immune system by enhancing the transformation of naive T cells into regulatory T cells (Treg cells). In the future, the physiological functions of D-mannose need to be further confirmed by more research data, in order to provide support for the application of D-mannose in functional foods and biomedicine. This review introduces the recent progress of studies on the production technology, metabolic pathways, physiological functions and application of D-mannose.
- D-mannose,
- production process,
- metabolism,
- physiological function

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References

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