Research Progress of Lateral Flow Immunoassay in Food Safety

YAN Lingzhi

doi:10.13386/j.issn1002-0306.2021070031

Volume 43 Issue 4

Feb. 2022

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Science and Technology of Food Industry > 2022 > 43(4): 1-11. > DOI: 10.13386/j.issn1002-0306.2021070031

YAN Lingzhi. Research Progress of Lateral Flow Immunoassay in Food Safety[J]. Science and Technology of Food Industry, 2022, 43(4): 1−11. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021070031.

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Research Progress of Lateral Flow Immunoassay in Food Safety

YAN Lingzhi

Department of Life Science, Yuncheng University, Yuncheng 044000, China

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Received Date: July 04, 2021
Accepted Date: December 07, 2021
Available Online: December 15, 2021

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Abstract

Abstract

lateral flow immunoassay (LFIA) not only effectively combines the separation ability of chromatography technology and the excellent specificity of immunoassay methods, but also provides an ideal platform for the on-site detection of food safety with advantages of easy operation, rapid detection and low cost. Gold nanoparticle is a commonly used signal label in the field of LFIA analysis. Unfortunately, conventional gold-based LFIA often suffers from drawbacks of low sensitivity, which can only satisfy qualitative and semi-quantitative information on analyte concentrations. To improve the detection performance of LFIA, researchers have made significant efforts. In this contribution, the basic principle of LFIA is introduced and the recent technical improvements are systematically summarized, such as developing novel signal nanoparticles, signal enhancement method, multiplex target detection and different signal readout mode, etc. Meanwhile, this study discusses the shortcomings and the trend of LFIA, which would provide technical references for the development of rapid detection methods for food safety in China.
- lateral flow immunoassay,
- test strip,
- food safety,
- rapid detection technology

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References

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