WANG Yaning, ZHANG Gaopeng, YE Songmei, et al. Research Process of Preparation Methods and Product Development of Tablet Candy[J]. Science and Technology of Food Industry, 2022, 43(10): 426−433. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021050259.
Citation: WANG Yaning, ZHANG Gaopeng, YE Songmei, et al. Research Process of Preparation Methods and Product Development of Tablet Candy[J]. Science and Technology of Food Industry, 2022, 43(10): 426−433. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021050259.

Research Process of Preparation Methods and Product Development of Tablet Candy

More Information
  • Received Date: May 30, 2021
  • Available Online: March 06, 2022
  • As an emerging type of food pattern in the candy field, tablet candy develops rapidly with various advantages of sweeter breath, lively packaging, functionality and so on, which has captured researcher’s attention and motivated them to study the vast development of tablet candy in several potential fields. In this paper, development history, classification, preparation methods, excipients selection and product research status of tablet candy are reviewed. In recent years, the preparation method of tablet candy has gradually changed from batch processing to continuous processing. Its preparation methods and excipients selection are also closely related to the properties of raw materials. Therefore, modified preparation methods of tablet candy and more suitable excipients have become important factors to improve the quality of tablet candy. There are many kinds of tablet candy in the market favored by consumers, with an extensive product positioning, varying from children to teenagers to adults. Due to the public demand, the innovation of tablet candy is developing in the direction of specific functions. This paper provides a theoretical basis and reference for the in-depth research and comprehensive development of the tablet candy product.
  • [1]
    中国商业联合会. GB/T 23823-2009 糖果分类[S]. 北京: 中国标准出版社, 2009: 1−3.

    China General Chamber of Commerce. GB/T 23823-2009 Candy classify[S]. Beijing: China Standard Press, 2009: 1−3.
    [2]
    中国商业联合会. SB/T 10347-2017 糖果 压片糖果[S]. 北京: 中国标准出版社, 2017: 1

    China General Chamber of Commerce. SB/T 10347-2017 Candy tablet candy[S]. Beijing: China Standard Press, 2017: 1.
    [3]
    中国商业联合会. SB 10347-2001 压片糖果[S]. 北京: 中国标准出版社, 2001: 29.

    China General Chamber of Commerce. SB 10347-2001 Tablet candy[S]. Beijing: China Standard Press, 2001: 29.
    [4]
    中国商业联合会. SB/T 10347-2008 糖果 压片糖果[S]. 北京: 中国标准出版社, 2008: 2.

    China General Chamber of Commerce. SB/T 10347-2008 Candy tablet candy[S]. Beijing: China Standard Press, 2008: 2.
    [5]
    罗盖特亚洲应用开发中心. 无糖压片糖果专家[J]. 食品工业科技,2014,35(12):36−37. [Roquette Asia Application Development Center. Sugar free tablet candy expert[J]. Science and Technology of Food Industry,2014,35(12):36−37.

    Roquette Asia Application Development Center. Sugar free tablet candy expert[J]. Science and Technology of Food Industry, 2014, 35(12): 36-37.
    [6]
    何利祥, 黄昕, 江建云, 等. 一种低糖压片糖果及其制备方法: 中国, 201911050173.3[P]. 2021-05-04.

    HE L X, HUANG X, JIANG J Y, et al. A low sugar tablet candy and a preparation method thereof: China, 201911050173.3[P]. 2021-05-04.
    [7]
    李淑英, 王凤忠, 范蓓, 等. 一种纳豆激酶压片糖果及其制备方法: 中国, 202010219509.0[P]. 2020-06-16.

    LI S Y, WANG F Z, FAN B, et al. A nattokinase tablet candy and a preparation method thereof: China, 202010219509.0[P]. 2020-06-16.
    [8]
    黄远英, 肖健. 一种胶原软骨片压片糖果: 中国, 202011577575.1[P]. 2021-05-07.

    HUANG Y Y, XIAO J. A tablet candy made of collagen cartilage: China, 202011577575.1[P]. 2021-05-07.
    [9]
    宗叶良, 周志东, 李云华. 一种DHA藻油磷脂酰丝氨酸压片糖果及其制备方法: 中国, 201910013342. X[P]. 2019-04-19.

    ZONG Y L, ZHOU Z D, LI Y H. A DHA algal oil phosphatidylserine tablet candy and its preparation method: China, 201910013342. X[P]. 2019-04-19.
    [10]
    王秋辉, 陈隽翰, 章燎源. 一种多彩压片糖果的制作方法: 中国, 201911087961. X[P]. 2020-01-10.

    WANG Q H, CHEN J H, ZHANG L Y. A preparation method of colorful tablet candy: China, 201911087961. X[P]. 2020-01-10.
    [11]
    徐后龙, 林雁冰, 周香云, 等. 富硒黑莓压片糖果及其制备方法: 中国, 202010183092.7[P]. 2020-06-19.

    XU H L, LIN Y B, ZHOU X Y, et al. Selenium enriched blackberry tablet candy and its preparation method: China, 202010183092.7[P]. 2020-06-19.
    [12]
    陈琼. 燕窝胶原蛋白肽压片糖果: 中国, 201910403294.5[P]. 2020-11-17.

    CHEN Q. Tablet candy of bird’s nest collagen peptide: China, 201910403294.5[P]. 2020-11-17.
    [13]
    柳富杰, 韦巧艳, 李大成, 等. 蓝莓叶黄素压片糖果的工艺[J]. 食品工业,2019,40(11):30−33. [LIU F J, WEI Q Y, LI D C, et al. Process of pressed candy with blueberry and xanthophyll[J]. The Food Industry,2019,40(11):30−33.

    LIU F J, WEI Q Y, LI D C, et al. Process of pressed candy with blueberry and xanthophyll[J]. The Food Industry, 2019, 40(11): 30-33.
    [14]
    于飞. 一种苦瓜黄酮压片糖果: 中国, 202011477779.8[P]. 2021-05-07.

    YU F. A kind of Momordica charantia flavone tablet candy: China, 202011477779.8[P]. 2021-05-07.
    [15]
    罗宁, 陈志波, 余虎成. 一种有效改善肥胖排毒排脂的压片糖果制备方法: 中国, 201911014336.2[P]. 2021-04-23.

    LUO N, CHEN Z B, YU H C. A preparation method of tablet candy for effectively improving fat and toxin excretion: China, 201911014336.2[P]. 2021-04-23.
    [16]
    李想, 崔永成. 一种黑枸杞参精片压片糖果及其制备方法: 中国, 202110012332.1[P]. 2021-04-09.

    LI X, CUI Y C. A black wolfberry Shenjing tablet candy and a preparation method thereof: China, 202110012332.1[P]. 2021-04-09.
    [17]
    梁鑫淼, 王超然, 郭志谋, 等. 一种酸枣仁茯苓压片糖果及其制备方法: 中国, 201911064446. X[P]. 2021-05-07.

    LIANG X M, WANG C R, GUO Z M, et al. A sour jujube kernel Poria cocos tablet candy and a preparation method thereof: China, 201911064446. X[P]. 2021-05-07.
    [18]
    王恒禹, 郭冬梅, 余汪平, 等. 三七茎叶压片糖果的研制[J]. 西华大学学报(自然科学版),2019,38(5):69−72, 105. [WANG H Y, GUO D M, YU W P, et al. Development of pressed candy by stems and leaves of Panax notoginseng[J]. Journal of Xihua University (Natural Science Edition),2019,38(5):69−72, 105. doi: 10.3969/j.issn.1673-159X.2019.05.011

    WANG H Y, GUO D M, YU W P, et al. Development of pressed candy by stems and leaves of Panax notoginseng[J]. Journal of Xihua University(Natural Science Edition), 2019, 38(05): 69-72+105. doi: 10.3969/j.issn.1673-159X.2019.05.011
    [19]
    韩瑞超, 相雪, 谭璐佳, 等. 纳豆压片糖果的研制[J]. 安徽农业科学,2015,43(28):275−277. [HAN R C, XIANG X, TAN L J, et al. Development of natto pressed candy[J]. Journal of Anhui Agricultural Sciences,2015,43(28):275−277. doi: 10.3969/j.issn.0517-6611.2015.28.101

    HAN R C, XIANG X, TAN L J, et al. Development of natto pressed candy[J]. Journal of Anhui Agricultural Sciences, 2015, 43(28): 275-277. doi: 10.3969/j.issn.0517-6611.2015.28.101
    [20]
    王婷, 靳玉涵, 张雯雯, 等. 降脂型柿子果醋压片糖果的研制[J]. 内蒙古科技与经济,2020,18:102−104. [WANG T, JIN Y H, ZHANG W W, et al. Development of persimmon vinegar tablet candy[J]. Inner Mongolia Science Technology & Economy,2020,18:102−104.

    WANG T, JIN Y H, ZHANG W W, et al. Development of persimmon vinegar tablet candy[J]. Inner Mongolia Science Technology & Economy, 2020, 18: 102-104.
    [21]
    赵玉国, 丁勇, 梁爽, 等. 木糖醇压片糖果的研发[J]. 现代食品,2019,24:99−101. [ZHAO Y G, DING Y, LIANG S, et al. Development of xylitol tablet candy[J]. Modern Food,2019,24:99−101.

    ZHAO Y G, DING Y, LIANG S, et al. Development of xylitol tablet candy[J]. Modern Food, 2019, 24: 99-101.
    [22]
    孙强. 当归超微粉直接压片工艺及其片剂质量标准研究[D]. 天津: 天津大学, 2007: 10.

    SUN Q. Study on direct compression technique and quality control of angelica sinensis micropowder tablet[D]. Tianjin: Tianjin University, 2007: 10.
    [23]
    夏冬琪. 粉末直接压片法的应用研究[J]. 现代盐化工,2016,43(5):32−33. [XIA D Q. Study on the application of direct powder compression method[J]. Modern Salt and Chemical Industry,2016,43(5):32−33. doi: 10.3969/j.issn.1005-880X.2016.05.015

    XIA D Q. Study on the application of direct powder compression method[J]. Modern Salt and Chemical Industry, 2016, 43(5): 32-33. doi: 10.3969/j.issn.1005-880X.2016.05.015
    [24]
    向琴琴. 番茄红素微胶囊片剂的制备、质量检测及功能的研究[D]. 新疆: 新疆农业大学, 2015: 10.

    XIANG Q Q. Study on preparation process, quality and function of lycopene microcapsules tablets[D]. Xinjiang: Xinjiang Agricultural University, 2015: 10.
    [25]
    NAKAMURA S, TANAKA C, YUASA H, et al. Utility of microcrystalline cellulose for improving drug content uniformity in tablet manufacturing using direct powder compression[J]. AAPS PharmSciTech,2019,20(4):1−12.
    [26]
    陈盛君, 朱家壁, 祁小乐. 粉末直接压片常用辅料的粉体学性质评价[J]. 中国医药工业杂志,2013,44(10):1010−1013. [CHEN S J, ZHU J B, QI X L. Evaluation of micromeritic properties of excipients for direct compression[J]. Chinese Journal of Pharmaceuticals,2013,44(10):1010−1013.

    CHEN S J, ZHU J B, QI X L. Evaluation of micromeritic properties of excipients for direct compression[J]. Chinese Journal of Pharmaceuticals, 2013, 44(10): 1010-1013.
    [27]
    MURA P, VALLERI M, BALDANZI S, et al. Characterization and evaluation of the performance of different calcium and magnesium salts as excipients for direct compression[J]. International Journal of Pharmaceutics,2019,567:1−10.
    [28]
    SANCHEZ-BALLESTER N M, BATAILLE B, BENABBAS R, et al. Development of alginate esters as novel multifunctional excipients for direct compression[J]. Carbohydrate Polymers,2020,240:116280. doi: 10.1016/j.carbpol.2020.116280
    [29]
    ISMAIL H Y, SINGH M, ALBADARIN A B, et al. Complete two dimensional population balance modelling of wet granulation in twin screw[J]. International Journal of Pharmaceutics,2020,591:120018−120018. doi: 10.1016/j.ijpharm.2020.120018
    [30]
    KAMYAR R, LAURI PLA D, HUSAIN A, et al. Soft sensor for real-time estimation of tablet potency in continuous direct compression manufacturing operation[J]. International Journal of Pharmaceutics,2021,602:120624. doi: 10.1016/j.ijpharm.2021.120624
    [31]
    COGONI G, ANGELA LIU Y, HUSAIN A, et al. A Hybrid NIR-soft sensor method for real time in-process control during continuous direct compression manufacturing operations[J]. International Journal of Pharmaceutics,2021,602:120620. doi: 10.1016/j.ijpharm.2021.120620
    [32]
    ALAM M A, LIU Y A. An agile and robust in-line NIR potency deviation detection method for monitoring and control of a continuous direct compression process[J]. International Journal of Pharmaceutics,2021,601:120521. doi: 10.1016/j.ijpharm.2021.120521
    [33]
    WILMS A, TESKE A, MEIER R, et al. Implementing feedback granule size control in a continuous dry granulation line using controlled impeller speed of the granulation unit, compaction force and gap width[J]. Journal of Pharmaceutical Innovation,2020,3:1−11.
    [34]
    况弯弯, 伍振峰, 万娜, 等. 中药干法制粒的研究思路探讨: 基于干法制粒技术研究的国内外研究进展[J]. 中国中药杂志,2019,44(15):3195−3202. [KUANG W W, WU Z F, WAN N, et al. Discussion on research thought of dry granulation of traditional Chinese medicine: research progress at home and abroad based on dry granulation technology[J]. China Journal of Chinese Materia Medica,2019,44(15):3195−3202.

    KUANG W W, WU Z F, WAN N, et al. Discussion on research thought of dry granulation of traditional Chinese medicine: research progress at home and abroad based on dry granulation technology[J]. China Journal of Chinese Materia Medica, 2019, 44(15): 3195-3202.
    [35]
    LINNET S A, KVISTGAARD V T, JUKKA R, et al. The relevance of granule fragmentation on reduced tablet ability of granules from ductile or brittle materials produced by roll compaction/dry granulation[J]. International Journal of Pharmaceutics,2021,592:120035. doi: 10.1016/j.ijpharm.2020.120035
    [36]
    SKELBAEK-PEDERSEN A, VILHELMSEN T, WALLAERT V, et al. Quantification of fragmentation of pharmaceutical materials after tableting[J]. Journal of Pharmaceutical Sciences,2019,108(3):1246−1253. doi: 10.1016/j.xphs.2018.10.040
    [37]
    WIEDEY R, ŠIBANC R, WILMS A, et al. How relevant is ribbon homogeneity in roll compaction/dry granulation and can it be influenced?[J]. European Journal of Pharmaceutics and Biopharmaceutics,2018,133:232−239. doi: 10.1016/j.ejpb.2018.10.021
    [38]
    BERKENKEMPER S, KEIZER H L, LINDENBERG M, et al. Functionality of disintegrants with different mechanisms after roll compaction[J]. International Journal of Pharmaceutics,2020,584:119434. doi: 10.1016/j.ijpharm.2020.119434
    [39]
    JOANA G C, PRAKASH P S S, LEOPOLD CLAUDIA S, et al. Application of aquasolv lignin in ibuprofen-loaded pharmaceutical formulations obtained via direct compression and wet granulation[J]. International Journal of Biological Macromolecules,2021,174:229−239. doi: 10.1016/j.ijbiomac.2021.01.064
    [40]
    MANGWANDI C, LIU J T, ALBADARIN A B, et al. High shear granulation of binary mixtures: Effect of powder composition on granule properties[J]. Powder Technology,2015,270:424−434. doi: 10.1016/j.powtec.2014.06.021
    [41]
    崔向龙. 银杏叶片高速剪切湿法制粒工艺设计及控制[D]. 北京: 北京中医药大学, 2017: 13−15.

    CUI X L. Design and control of high shear wet granulation process for ginkgo tablet[D]. Beijing: Beijing University of Chinese Medicine, 2017: 13−15.
    [42]
    MAHDI F, HASSANPOUR A, MULLER F. An investigation on the evolution of granule formation by in-process sampling of a high shear granulator and design[J]. Chemical Engineering Research,2018,129:403−411. doi: 10.1016/j.cherd.2017.10.038
    [43]
    TAIPALE-KOVALAINEN K, KETOLAINEN J, KORHONEN O, et al. Converting a batch based high-shear granulation process to a continuous dry granulation process; a demonstration with ketoprofen tablets[J]. European Journal of Pharmaceutical Sciences,2020,151:105381. doi: 10.1016/j.ejps.2020.105381
    [44]
    GUPTA S, THOOL P, MERUVA S, et al. Development of low dose micro-tablets by high shear wet granulation process[J]. International Journal of Pharmaceutics,2020,587:119571. doi: 10.1016/j.ijpharm.2020.119571
    [45]
    张怡睿, 卓小菲, 刘芷粤, 等. 芒果压片糖的制备工艺研究[J]. 农产品加工,2019(4):47−49,52. [ZHANG Y R, ZHUO X F, LIU Z Y, et al. Study on process of tablet candy with mango powder[J]. Farm Products Processing,2019(4):47−49,52.

    ZHANG Y R, ZHUO X F, LIU Z Y, et al. Study on process of tablet candy with mango powder[J]. Farm Products Processing, 2019(4): 47-49, 52.
    [46]
    YE X Y, KALLAKUNTA V, KIM D W, et al. Effects of processing on a sustained release formulation prepared by twin-screw dry granulation[J]. Journal of Pharmaceutical Sciences,2019,108(9):2895−2904. doi: 10.1016/j.xphs.2019.04.004
    [47]
    SCHMIDT M, BÜCK A, TSOTSAS E. Experimental investigation of the influence of drying conditions on process stability of continuous spray fluidized bed layering granulation with external product separation[J]. Powder Technology,2017,320:474−482. doi: 10.1016/j.powtec.2017.07.012
    [48]
    杨娟, 冼嘉敏, 柯晓宜, 等. 番石榴叶陈皮压片糖果的制备及品质测定[J]. 食品工程,2020(4):22−26. [YANG J, XIAN J M, KE X Y, et al. Preparation and quality determination of tablet candy of extract from guava leaf and orange peel[J]. Food Engineering,2020(4):22−26. doi: 10.3969/j.issn.1673-6044.2020.04.007

    YANG J, XIAN J M, KE X Y, et al. Preparation and quality determination of tablet candy of extract from guava leaf and orange peel[J]. Food Engineering, 2020(4): 22-26. doi: 10.3969/j.issn.1673-6044.2020.04.007
    [49]
    张志红, 王晓婧, 崔林峰, 等. 植物原粉压片糖果品质影响因素的研究[J]. 食品与发酵科技,2017,53(1):59−62. [ZHANG Z H, WANG X J, CUI L F, et al. Plant powder pressed candy quality influence factors of research[J]. Food and Fermentation Sciences & Technology,2017,53(1):59−62.

    ZHANG Z H, WANG X J, CUI L F, et al. Plant powder pressed candy quality influence factors of research[J]. Food and Fermentation Sciences & Technology, 2017, 53(1): 59-62.
    [50]
    罗一甲, 刘文玉, 刘文翰, 等. 响应面优化枸杞复合压片糖果配方研究[J]. 现代食品,2020,4(4):76−80. [LUO Y J, LIU W Y, LIU W H, et al. Optimization on compound tablet candy formula of chinese wolfberry based on response surface method[J]. Morden Food,2020,4(4):76−80.

    LUO Y J, LIU W Y, LIU W H, et al. Optimization on compound tablet candy formula of chinese wolfberry based on response surface method[J]. Morden Food, 2020, 04: 76-80.
    [51]
    焦春伟, 谢意珍, 何春艳, 等. 一种灰树花活性多糖复合压片糖果及制备方法和用途: 中国, 202010756157.2[P]. 2020-11-03.

    JIAO C W, XIE Y Z, HE C Y, et al. A kind of compound tablet candy with active polysaccharide from ash tree flower and its preparation method and application: China, 202010756157.2[P]. 2020-11-03.
    [52]
    焦春伟, 何春艳, 马晓伟, 等. 一种富硒蛹虫草压片糖果及其制备方法: 中国, 202010755409. X[P]. 2020-11-06.

    JIAO C W, HE C Y, MA X W, et al. A selenium enriched cordyceps militaris tablet candy and its preparation method: China, 202010755409. X[P]. 2020-11-06.
    [53]
    杨亮, 常书源, 陈海瑜, 等. 桦褐孔菌压片糖果的制备工艺研究[J]. 化学工程师,2020,34(6):85−89. [YANG L, CHANG S Y, CHEN H Y, et al. Study on the preparation technology of tablet candy of Inonotus obliquus[J]. Chemical Engineer,2020,34(6):85−89.

    YANG L, CHANG S Y, CHEN H Y, et al. Study on the preparation technology of tablet candy of Inonotus obliquus[J]. Chemical Engineer, 2020, 34(6): 85-89.
    [54]
    于伟茹, 宋慧妍, 徐欣宇, 等. 基于模糊数学结合响应面法优化蓝莓果渣压片糖果配方[J]. 食品工业,2020,41(8):169−173. [YU W R, SONG H Y, XU X Y, et al. Formulation optimization of blueberry pomace pressed candy based on fuzzy mathematics combined with response surface methodology[J]. The Food Industry,2020,41(8):169−173.

    YU W R, SONG H Y, XU X Y, et al. Formulation optimization of blueberry pomace pressed candy based on fuzzy mathematics combined with response surface methodology[J]. The Food Industry, 2020, 41(8): 169-173.
    [55]
    朱保全. 一种人参葛根压片糖果及其制备方法: 中国, 201910754494.5[P]. 2019-11-22.

    ZHU B Q. A kind of ginseng Pueraria tablet candy and its preparation method: China, 201910754494.5[P]. 2019-11-22.
    [56]
    魏建华, 赵花, 曹立军, 等. 一种增加骨密度的压片糖果及其制备方法: 中国, 202010041373.9[P]. 2020-04-10.

    WEI J H, ZHAO H, CAO L J, et al. A tablet candy for increasing bone density and a preparation method thereof: China, 202010041373.9[P]. 2020-04-10.
    [57]
    李博. 一种益生菌压片糖果的制备方法: 中国, 202010612546.8[P]. 2020-09-15.

    LI B. A preparation method of probiotic tablet candy: China, 202010612546.8[P]. 2020-09-15.
    [58]
    VERONICA N, LIEW C V, HENG P W S. Insights on the role of excipients and tablet matrix porosity on aspirin stability[J]. International Journal of Pharmaceutics,2020,580:119218. doi: 10.1016/j.ijpharm.2020.119218
    [59]
    ARKADIUSZ H, SEBASTIAN C, JANINA L. Impact of co-processed excipient particles solidity and circularity on critical quality attributes of orodispersible minitablets[J]. Powder Technology,2021,387:497−508.
    [60]
    KOSKELA J, MORTON D A V, STEWART P J, et al. The effect of mechanical dry coating with magnesium stearate on flowability and compactibility of plastically deforming microcrystalline cellulose powders[J]. International Journal of Pharmaceutics,2018,537(1-2):64−72. doi: 10.1016/j.ijpharm.2017.11.068
    [61]
    国家药典委员会. 中国药典. 四部[S]. 北京: 中国医药科技出版社, 2020.

    Chinese Pharmacopoeia Commission. Chinese Pharmacopoeia. Volume 4[S]. Beijing: China Medical Science Press, 2020.
    [62]
    DESAI P M, LIEW C V, HENG P. Review of disintegrants and the disintegration phenomena[J]. Journal of Pharmaceutical Sciences,2016:2545−2555.
    [63]
    张强宗. 粉末直接压片对辅料的应用要求探讨[J]. 海峡药学,2015,27(9):20−21. [ZHANG Q Z. Discussion on the application requirements of excipients for direct powder compression[J]. Strait Pharmaceutical Journal,2015,27(9):20−21. doi: 10.3969/j.issn.1006-3765.2015.09.007

    ZHANG Q Z. Discussion on the application requirements of excipients for direct powder compression[J]. Strait Pharmaceutical Journal, 2015, 27(9): 20-21. doi: 10.3969/j.issn.1006-3765.2015.09.007
    [64]
    BENABBAS R, SANCHEZ-BALLESTER N M, BATAILLE B, et al. Development and pharmaceutical performance of a novel co-processed excipient of alginic acid and microcrystalline cellulose[J]. Powder Technology,2021,378:576−584. doi: 10.1016/j.powtec.2020.10.027
    [65]
    CHAHEEN M, SANCHEZ-BALLESTER N M, BATAILLE B, et al. Development of coprocessed chitin-calcium carbonate as multifunctional tablet excipient for direct compression[J]. Journal of Pharmaceutical Sciences,2018,107(8):2152−2159. doi: 10.1016/j.xphs.2018.04.013
    [66]
    CHAHEEN M, BATAILLE B, YASSINE A, et al. Development of coprocessed chitin-calcium carbonate as multifunctional tablet excipient for direct compression, Part 2: Tableting properties[J]. Journal of Pharmaceutical Sciences,2019,108(10):3319−3328. doi: 10.1016/j.xphs.2019.05.021
    [67]
    DZIEMIDOWICZ K, LOPEZ F L, BOWLES B J, et al. Co-processed excipients for dispersible tablets—part 2: Patient acceptability[J]. AAPS PharmSciTech,2018,19(6):2646−2657. doi: 10.1208/s12249-018-1104-2
    [68]
    毕勇, 李祥祥. 共处理辅料及其在制剂中的应用研究[J]. 安徽科技,2019(9):48−50. [BI Y, LI X X. Research of co-processed excipients and its applications in preparation[J]. Anhui Science & Technology,2019(9):48−50. doi: 10.3969/j.issn.1007-7855.2019.09.018

    BI Y, LI X X. Research of co-processed excipients and its applications in preparation[J]. Anhui Science & Technology, 2019(9): 48-50. doi: 10.3969/j.issn.1007-7855.2019.09.018
    [69]
    CONCEIÇÃO L L D, VALENZUELA B M J, TAVARES B R, et al. Use of scanning electron microscopy with energy dispersive spectroscopy to detect metallic contamination in candies[J]. Food Packaging and Shelf Life,2021,28:100649. doi: 10.1016/j.fpsl.2021.100649
  • Cited by

    Periodical cited type(22)

    1. 黄宝玲,陈海彬,李咏梅,刘媛. 澳洲坚果青皮不同提取物的总多酚及抗氧化能力测定. 农产品加工. 2024(04): 67-70 .
    2. 贺玉香,林咏翔. 几种美白原料配伍对其功能特性的影响. 食品工业. 2024(06): 130-135 .
    3. 晏飞利,刘丹,陈艾萌,吕向阳,马林. 迷宫栓孔菌子实体提取物的抗氧化活性研究. 安徽农业科学. 2023(03): 167-170+175 .
    4. 王萍,刘慧,付湘晋,李柏海. 13种植物多酚提取物抗氧化活性分析及其对冻藏未漂洗鱼糜品质的影响研究. 食品安全质量检测学报. 2023(16): 50-56 .
    5. 葛鑫会,孟继坤,张楠,苗雨欣,张秀清. 五台山野生食用菌酚类物质组成及抗氧化活性分析. 中国食用菌. 2022(04): 56-63 .
    6. 徐佳亨,张佳蒙,李远鹏,蒋黎艳. 石榴籽营养成分提取及其功能和应用研究进展. 山东化工. 2021(09): 61-63+65 .
    7. 热阳古·阿布拉,孙艳美,阿卜杜拉·玉苏普. 不同品种石榴籽总生物碱抗氧化活性研究. 广东化工. 2021(14): 14-15+39 .
    8. 牛永浩,张碧玲,吴亮亮,郭彦君,刘新荣. 礼泉县石榴产业发展现状研究. 陕西农业科学. 2021(08): 91-94 .
    9. 李建科,孟永宏,刘柳,王晓宇,王晓龙,吴晓霞,骆莹. 我国食品工业副产物资源化利用现状. 食品科学技术学报. 2021(06): 1-13 .
    10. 李颜桃,仲崇华,张健荣,曲逸文,毕师诚,马跃,赵婵娟,曹立亭. 沙棘籽多酚超声耦合真空提取工艺的研究. 中国粮油学报. 2021(11): 151-156 .
    11. 何文,李瀚鑫,王晰雯,叶春林. 三叶青不同萃取部位抗氧化活性. 食品工业. 2020(02): 151-155 .
    12. 王杰,夏彩芬,周丽,田翔. 苦槠粉/羧甲基壳聚糖膜的制备及抗氧化能力评价. 湖北农业科学. 2020(08): 116-120 .
    13. 卢艺惠,张睿,王朝宇,毕艳红,赵祥杰,李明依,沈源,王俊淇. 苹果籽壳色素的体外抗氧化性及抑菌性研究. 包装与食品机械. 2020(03): 34-38 .
    14. 刘庆,陈琼,李化强,吴菲菲,彭洁,王美英,胡平. 不同溶剂对石榴籽提取物抗氧化活性的影响. 邵阳学院学报(自然科学版). 2020(04): 70-76 .
    15. 范尧珠,王鑫,顾思远,马铃. 石榴籽在酥性饼干中的工艺. 食品工业. 2020(08): 98-103 .
    16. 陈凤清,孙秋芹,傅玉全,孙士红,李童,张慧男,丛建民. 黄瓜籽粉止咳成分提取工艺及生物活性探究. 白城师范学院学报. 2020(05): 27-32+69 .
    17. 李国锋. 抗运动疲劳食源性活性成分的研究进展. 食品工业科技. 2020(24): 344-353 . 本站查看
    18. 阿力木江·麦斯依提,皮尔地瓦斯,李义亮,艾克拜尔·艾力,王志,麦麦提艾力·买买提明,克力木·阿不都热依木. 复方比黑马尔江胶囊治疗胃食管反流病的疗效与安全性研究. 中华胃食管反流病电子杂志. 2020(03): 154-157 .
    19. 曹小燕,杨海涛. 响应面法优化超声辅助提取荠菜多酚工艺及其抗氧活性研究. 食品工业科技. 2019(02): 223-228+232 . 本站查看
    20. 陈义磊,木尼热·阿布都克力木,尹学博,王飒,木合塔尔·吐尔洪. 库鲁木提草中多酚的提取工艺优化及其抗氧化活性的研究. 南开大学学报(自然科学版). 2019(04): 10-16 .
    21. 尹乐斌,杨爱莲,刘丹,周娟,李立才,邓鹏. 石榴籽水提物的制备及其体外抗氧化活性. 食品工业. 2019(10): 221-224 .
    22. 洪璇,陈仲巍,李鹤宾,杨丙晔,罗浩虹,林启凰. 鸡桑叶多酚提取工艺优化及其抗氧化性能. 食品工业科技. 2018(13): 73-77+172 . 本站查看

    Other cited types(4)

Catalog

    Article Metrics

    Article views (1231) PDF downloads (170) Cited by(26)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return