Citation: | CHEN Jingjing, BAI Xueyuan, BIAN Shuai, et al. Screening and Evaluation of Anti-aging Activity of Ginsenosides Based on Saccharomyces cerevisiae System[J]. Science and Technology of Food Industry, 2022, 43(1): 1−9. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021050033. |
[1] |
周佳, 康亚妮. 单细胞衰老研究的模式生物——酿酒酵母[J]. 生命科学,2013,25(5):504−510. [ZHOU J, KANG Y N. Saccharomyces cerevisiae: A model organism for single cell aging research[J]. Life Sciences,2013,25(5):504−510.
|
[2] |
周玉枝, 闫明亮, 高丽, 等. 衰老动物模型的研究及其在抗衰老药物活性筛选中的应用[J]. 中草药,2017,48(6):1061−1071. [ZHOU Y Z, YAN M L, GAO L, et al. Study on aging animal model and its application in the screening of anti-aging drug activity[J]. Chinese Traditional and Herbal Medicine,2017,48(6):1061−1071.
|
[3] |
SHI G, LIU D, ZHOU B, et al. Ginsenoside Rb1 alleviates oxidative low-density lipoprotein-induced vascular endothelium senescence via the SIRT1/Beclin-1/Autophagy axis[J]. Cardiovasc Pharmacol,2020,75(2):155−167. doi: 10.1097/FJC.0000000000000775
|
[4] |
KAEBERLEIN M, POWERS R W, STEFFEN K K, et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients[J]. Science,2005,310(5751):1193−1196. doi: 10.1126/science.1115535
|
[5] |
BONAWITZ N D, CHATENAY-LAPOINTE M, PAN Y, et al. Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression[J]. Cell Metab,2007,5(4):265−277. doi: 10.1016/j.cmet.2007.02.009
|
[6] |
HE CHONG, ZHOU CHUANKAI, KENNEDY BRIAN K. The yeast replicative aging model[J]. Biochimica Et Biophysica Acta,2018,1864(9):2690−2696. doi: 10.1016/j.bbadis.2018.02.023
|
[7] |
莫睿, 魏智民, 杨云生. 抗衰老机制研究进展[J]. 解放军医学杂志,2017,42(8):743−748. [MO R, WEI Z M, YANG Y S. Research progress on anti-aging mechanism[J]. Chinese PLA Medical Journal,2017,42(8):743−748.
|
[8] |
HARMAN D. The aging process[J]. Proceedings of the National Academy of Sciences of the United States of America,1981,78(11):7124−7128. doi: 10.1073/pnas.78.11.7124
|
[9] |
尹亚辉, 安文涛, 董亮, 等. 不同世代酿酒酵母胞内抗氧化酶活性变化[J]. 食品科技,2013,38(8):38−41,47. [YIN Y H, AN W T, DONG L, et al. Changes of intracellular antioxidant enzyme activities of Saccharomyces cerevisiae in different generations[J]. Food Science and Technology,2013,38(8):38−41,47.
|
[10] |
王郅媛, 王友升, 李丽萍. 抗衰老研究新模型—酵母细胞活性氧代谢研究进展[J]. 食品科学,2012,33(7):354−358. [WANG Z Y, WANG Y S, LI L P. A new model for anti-aging research-research progress of active oxygen metabolism in yeast cells[J]. Food Science,2012,33(7):354−358.
|
[11] |
张爱利. 酿酒酵母衰老机制研究进展[J]. 生命科学,2009,21(2):303−306. [ZHANG A L. Researchprogress on senescence mechanism of Saccharomyces cerevisiae[J]. Life Science,2009,21(2):303−306.
|
[12] |
钟云. Candidatus liberibacter asiaticus诱导的柑橘转录组学及蛋白组学研究[D]. 长沙: 湖南农业大学, 2012.
ZHANG Y. Transcriptomic and proteomic studies of Candidatus liberibacter asiaticus in citrus[D]. Changsha: Hunan Agricultural University, 2012.
|
[13] |
于雪妮, 冯小刚, 张建民, 等. 人参化学成分与药理作用研究新进展[J]. 人参研究,2019,31(1):47−51. [YU X N, FENG X G, ZHANG J M, et al. New progress in research on chemical constituents and pharmacological effects of ginseng[J]. Ginseng Research,2019,31(1):47−51. doi: 10.3969/j.issn.1671-1521.2019.01.012
|
[14] |
向玥, 陈粼波, 姚辉, 等. 人参皂苷Rg1对D-半乳糖所致衰老小鼠海马的保护机制[J]. 中草药,2017,48(18):3789−3795. [XIANG Y, CHEN L B, YAO H, et al. Protective mechanism of Ginsenoside Rg1 on hippocampus of aging mice induced by D-galactose[J]. Chinese Herbal Medicine,2017,48(18):3789−3795. doi: 10.7501/j.issn.0253-2670.2017.18.019
|
[15] |
TANG Y L, ZHOU Y, WANG Y P, et al. Ginsenoside Rg1 protects against Sca-1+ HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model[J]. Experimental and Therapeutic Medicine,2020,20(2):1245−1252. doi: 10.3892/etm.2020.8810
|
[16] |
WANG Z L, CHEN L B, QIU Z, et al. Ginsenoside Rg1 ameliorates testicular senescence changes in D-gal-induced aging mice via anti-inflammatory and antioxidative mechanisms[J]. Mol Med Rep,2018,17(5):6269−6276.
|
[17] |
乔巨慧, 赵大庆, 刘美辰, 等. 人参总皂苷对D-半乳糖致PC12细胞衰老的改善作用及其机制研究[J]. 中国药房,2020,31(24):2993−2999. [QIAO J H, ZHAO D Q, LIU M C, et al. Effect of ginseng total saponins on the aging of PC12 cells induced by D-galactose[J]. Pharmacy of China,2020,31(24):2993−2999. doi: 10.6039/j.issn.1001-0408.2020.24.08
|
[18] |
李成鹏, 张梦思, 刘俊, 等. 人参皂苷Rg1延缓脑衰老机制研究[J]. 中国中药杂志,2014,39(22):4442−4447. [LI C P, ZHANG M S, LIU J, et al. Mechanism of ginsenoside Rg1 in delaying brain aging[J]. Chinese Journal of Traditional Chinese Medicine,2014,39(22):4442−4447.
|
[19] |
彭彬, 王朝丽, 冯丽, 等. 人参皂苷Rg1调控神经干细胞衰老作用及机制探讨[J]. 中国细胞生物学学报,2011,33(10):1116−1122. [PENG B, WANG C L, FENG L, et al. Effects of ginsenoside Rg1 on neural stem cell senescence[J]. Chinese Journal of Cell Biology,2011,33(10):1116−1122.
|
[20] |
柯世业, 石光耀, 刘定辉, 等. 人参皂苷Rb1通过Sirt3/SOD2通路延缓高糖诱导的人脐静脉内皮细胞衰老[J]. 中山大学学报(医学版),2019,40(3):329−336. [KE S Y, SHI G Y, LIU D H, et al. Ginsenoside Rb1 prevents senescence of human umbilical vein endothelial cells induced by high glucose through Sirt3/SOD2 pathway[J]. Journal of Sun Yat-sen University(Medical Edition),2019,40(3):329−336.
|
[21] |
刘春红, 汤燚聪, 高瑜培, 等. 鹿茸乙醇提取物对秀丽隐杆线虫抗衰老的作用[J/OL]. 食品工业科技: 1−8 [2021-04-20]. https: //doi. org/10.13386/j. issn1002-0306.2020060027.
LIU C H, TANG Y C, GAO Y P, et al. Antler antler ethanol extract on the anti-aging effect of Caedihabditis elegans[J/OL]. Science and Technology of Food Industry : 1−8 [2021-04-20]. https://doi.org/10.13386/j.issn1002-0306.2020060027.
|
[22] |
时桂芹, 任菲, 谢冰宗, 等. 高糖胁迫对酿酒酵母抗氧化活性及代谢的影响[J]. 食品工业科技,2019,40(20):94−100. [SHI G Q, REN F, XIE B Z, et al. Effects of high sugar stress on antioxidant activity and metabolism of Saccharomyces cerevisiae[J]. Science and Technology of Food Industry,2019,40(20):94−100.
|
[23] |
袁方, 朴永哲, 刘巨涛, 等. 外源肌醇、柚皮苷及姜黄素对酿酒酵母抗衰老性能影响[J]. 酿酒科技,2014,4(7):43−47. [YUAN F, PU Y Z, LIU J T, et al. Effects of exogenous inositol, naringin and curcumin on anti-aging performance of Saccharomyces cerevisiae[J]. Brewing Technology,2014,4(7):43−47.
|
[24] |
ISWARYA A, ANJUGAM M, SHANTHINI S, et al. Protective activity of beta-1, 3-glucan binding protein against AAPH induced oxidative stress in Saccharomyces cerevisiae[J]. International Journal of Biological Macromolecules,2019,138:890−902. doi: 10.1016/j.ijbiomac.2019.07.130
|
[25] |
吴奇. 人参皂苷Rg1延缓神经干细胞衰老与调控Nrf2/ARE信号通路关系的研究[D]. 重庆: 重庆医科大学, 2020.
WU Q. Study on the relationship between ginsenoside Rg1 delaying neural stem cell senescence and regulating Nrf2/ARE signaling pathway[D]. Chongqing: Chongqing Medical University, 2020.
|
[26] |
王敏, 廖林锋, 孙晓宇, 等. 延衰组合物对酵母细胞寿命及氧化应激的研究[J]. 食品研究与开发,2021,42(12):1−7. [WANG M, LIAO L F, SUN X Y, et al. Studies on the longevity and oxidative stress of yeast cells by prolonging decay composition[J]. Food Research and Development,2021,42(12):1−7. doi: 10.12161/j.issn.1005-6521.2021.12.001
|
[27] |
OHKAWA H, OHISHI N, YAGI K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction[J]. Anal Biochem,1979,95(2):351−358. doi: 10.1016/0003-2697(79)90738-3
|
[28] |
石润霖. 不同营养物质对酵母生长及衰老的影响[D]. 大连: 大连工业大学, 2015.
SHI R L. Effects of different nutrients on growth and senescence of yeast[D]. Dalian: Dalian University of Technology, 2015.
|
[29] |
袁方. 酵母抗老化研究[D]. 大连: 大连工业大学, 2014.
YUAN F. Study on anti-aging of yeast[D]. Dalian: Dalian University of Technology, 2014.
|
[30] |
MEDKOUR Y, MOHAMMAD K, ARLIA-CIOMMO A, et al. Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast[J]. Oncotarget,2019,10(56):5780−5816. doi: 10.18632/oncotarget.27209
|
[31] |
BATUBARA I, ASTUTI R I, PRASTYA M E, et al. The antiaging effect of active fractions and ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid isolated from Adenostemma lavenia(L.) O. kuntze at the cellular level[J]. Antioxidants,2020,9(8):719. doi: 10.3390/antiox9080719
|
[32] |
HAMANACA R, CHANDEL N. Mitochondrial reactive oxygen species regulate cellular signalling and dictate biological outcome[J]. Trends in Biochemical Sciences,2010,35:505−513. doi: 10.1016/j.tibs.2010.04.002
|
[33] |
王高坚, 王珍珍, 李嘉嘉, 等. 蓝莓酵素的体外抗氧化及对秀丽隐杆线虫的氧化应激保护作用[J/OL]. 食品工业科技: 1−13 [2021-01-19]. https://doi.org/10.13386/j.issn1002-0306.2020110157.
WANG G J, WANG Z Z, LI J J, et al. Effects of blueberry enzyme on antioxidant activity and oxidative stress protection against Caenorhabditis elegans[J/OL]. Science and Technology in Food Industry : 1−13 [2021-01-19]. https://doi.org/10.13386/j.issn1002-0306.2020110157.
|