Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane

ZHANG Xuan; TIAN Mingshuo; WANG Jian; GAO Mingkun; GAO Yuhang; LIU Yuan; XU Donghui; LIU Guangyang

doi:10.13386/j.issn1002-0306.2021040167

Volume 43 Issue 17

Aug. 2022

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Science and Technology of Food Industry > 2022 > 43(17): 424-434. > DOI: 10.13386/j.issn1002-0306.2021040167

ZHANG Xuan, TIAN Mingshuo, WANG Jian, et al. Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane[J]. Science and Technology of Food Industry, 2022, 43(17): 424−434. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021040167.

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Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane

1.
College of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality & Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou 075000, China
2.
The Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products (Beijing), Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China
3.
College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China

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Received Date: April 25, 2021
Available Online: June 25, 2022

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Abstract

Abstract

Glucosinolates are a kind of important sulfur-containing anionic hydrophilic natural products in cruciferous vegetables. Under the catalysis of endogenous myrosinase, glucosinolates can be hydrolyzed to produce active substances with anti-cancer, anti-oxidation, antimicrobial and other effects, which have attracted wide attention of researchers. Sulforaphane is a thioglucose monomer with the best anticancer effect and the strongest efficacy. As an effective component of drugs or functional foods, it has high research value and broad application prospects. In this study, the source, structure, properties, functional activities of sulforaphane are summarized, and its extraction technology, separation and purification methods and anticancer applications are systematically introduced. The research prospect is discussed and anticipated, in order to provide research basis and technical support for the research and development of sulforaphane functional components and high value-added utilization.
- sulforaphane,
- structural properties,
- extraction method,
- separation and purification,
- anticancer application

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References (91)

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