ZHU Qipeng, LI Xiaodong, LIU Lu, et al. ACE Inhibitory Rate, Bitterness and Stability of Microencapsulated Extracts of Ginger, Chinese Wolfberry and Gardenia jasminoides[J]. Science and Technology of Food Industry, 2021, 42(22): 47−54. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021020040.
Citation: ZHU Qipeng, LI Xiaodong, LIU Lu, et al. ACE Inhibitory Rate, Bitterness and Stability of Microencapsulated Extracts of Ginger, Chinese Wolfberry and Gardenia jasminoides[J]. Science and Technology of Food Industry, 2021, 42(22): 47−54. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021020040.

ACE Inhibitory Rate, Bitterness and Stability of Microencapsulated Extracts of Ginger, Chinese Wolfberry and Gardenia jasminoides

More Information
  • Received Date: February 04, 2021
  • Available Online: September 08, 2021
  • This study obtained mixed alcohol extracts of ginger, Chinese wolfberry, and Gardenia jasminoides by pulverization and ultrasound. Maltodextrin, modified starch, and a mixture of both with gelatin as the composite embedding wall material, and spray dried into microcapsules. The embedding rate, ACE(angiotensin-convertion enzyme) inhibition rate, hygroscopicity, total phenol content(TPC), bitterness degree were determined, and infrared spectroscopy(FTIR), scanning electron microscope(SEM), thermogravimetric analyzer(TGA) were used to study the structure and thermal stability of microencapsulated particles. The results showed that the best wall material of the microcapsules was a 1:1 mixture of maltodextrin and modified starch. At this time, the embedding rate was 75.24%(P<0.05). The infrared spectrum analysis showed that the extract was successfully embedded by the wall material, and forming a starch/dextrin-phenol-gelatin polymers. Compared with non-embedded and single maltodextrin, modified starch embedding, the bitterness of the microcapsules embedded with a 1:1 mixture of maltodextrin and modified starch as the wall material was significantly reduced(P<0.05), and the hygroscopicity was reduced from 52.83 to 16.04 g/(100 g). The release rate of phenols in the microcapsules after gastrointestinal digestion was 69.64%, and the ACE inhibition rate was 49.64%(P<0.05). Thus, modified starch and maltodextrin in weight ratio 1:1 mixing, as the microencapsulated medicinal and food homologous extract of the wall material, could significantly reduce bitterness and improve product stability. After storage at room temperature for seven days, the ACE inhibition rate was still as high as 22.36%.
  • [1]
    王岩, 张博, 李建华. 姜黄素对肾脏保护作用机制的研究进展[J]. 中国现代医生,2009,47(35):23−26. [WANG Y, ZHANG B, LI J H. Mechanisms of renal protection of curcumine: Research advance[J]. China Modern Doctor,2009,47(35):23−26. doi: 10.3969/j.issn.1673-9701.2009.35.010
    [2]
    孙萌, 高永红. 姜黄素对老年高血压大鼠肾脏血管紧张素转化酶/血管紧张素转化酶2平衡的调节作用[J]. 中华临床医师杂志,2015,9(11):2169−2173. [SUN M, GAO Y H. Effect of curcumin on the balance of ACE and ACE2 in kidney of old hypertensive rats[J]. Chinese Journal of Clinicians,2015,9(11):2169−2173.
    [3]
    ZHUANG X D, LIAO L Z, DONG X B, et al. Design, synthesis, and antihypertensive activity of curcumin-inspired compounds via ACE inhibition and vasodilation, along with a bioavailability study for possible benefit in cardiovascular diseases[J]. Drug Design, Development and Therapy,2016,10:129−139.
    [4]
    陶瑶, 张亚辉, 陶秀娟, 等. 枸杞蛋白酶解液对自发性高血压大鼠的降血压机制研究[J]. 食品工业科技,2019,40(10):308−313, 344. [TAO Y, ZHANG Y H, TAO X J, et al. Anti-hypertensive mechanism of the enzymatic hydrolysate of Lycium barbarum protein on spontaneously hypertensive rats[J]. Science and Technology of Food Industry,2019,40(10):308−313, 344.
    [5]
    潘媛, 陈大霞, 李隆云. 栀子环烯醚萜类物质生物合成相关基因的挖掘与分析[J]. 分子植物育种,2020,18(12):3923−3931. [PAN Y, CHEN D X, LI L Y. Analysis of transcriptonme and excavation iridoid biosynthesis pathway key genes in gardenia Jasmino ellis[J]. Molecular Plant Breeding,2020,18(12):3923−3931.
    [6]
    LIU F Z, LI Y B, MENG, et al. Study on mechanism of iridoid glycosides derivatives from Fructus gardeniae in Jiangxi province by network pharmacology[J]. Evidence-Based Complementary and Alternative Medicine,2020(23):1−12.
    [7]
    CHEN S C, PENG S, ZHAO X, et al. Gardenia jasminoides has therapeutic effects on LNNA induced hypertension in vivo[J]. Molecular Medicine Reports,2017,15(6):43−60.
    [8]
    曹虹虹, 严维花, 郭爽, 等. 栀子姜炙工艺及姜炙前后化学成分变化研究[J]. 中国中药杂志,2019,44(24):5413−5420. [CAO H H, YAN W H, GUO S, et al. Technology optimization of Gardeniae fructus processed with ginger juice and composition changes after processing[J]. China Journal of Chinese Materia Medica,2019,44(24):5413−5420.
    [9]
    ZHANG G, CHEN S S, ZHOU W, et al. Rapid qualitative and quantitative analyses of eighteen phenolic compounds from Lycium ruthenicum murray by UPLC-Q-Orbitrap MS and their antioxidant activity[J]. Food Chemistry,2018,269:150−156. doi: 10.1016/j.foodchem.2018.06.132
    [10]
    ZHANG J Q, CHEN C, FU X. Fructus mori L. polysaccharide-iron chelates formed by self-embedding with iron(III) as the core exhibit good antioxidant activity[J]. Food & Function,2019,10(6):3150−3160.
    [11]
    SUBHAM B, PRONOBESH C, ANIMESH G, et al. Influence of process variables on essential oil microcapsule properties by carbohydrate polymer-protein blends[J]. Carbohydrate Polymers,2013,93(2):691−697. doi: 10.1016/j.carbpol.2013.01.028
    [12]
    曹祥薇, 胡蓓, 侯宁, 等. 明胶/麦芽糊精复合壁材制备香精微胶囊[J]. 黑龙江大学工程学报,2017,8(2):47−50. [CAO X W, HU B, HOU N, et al. Preparation of perfume microcapsule by compound of gelatin and malt dextrin[J]. Journal of Engineering of Heilongjiang University,2017,8(2):47−50.
    [13]
    庄建鹏, 李晓东, 杜玲玲, 等. 微胶囊化乳清蛋白水解物的降胆固醇活性、苦味和稳定性研究[J]. 中国食品学报,2017,17(1):31−38. [ZHUANG J P, LI X D, DU L L, et al. Study on the hypocholesterolemic activity, bitter taste and stability of microencapsulation of whey protein concentrate hydrolysate[J]. Journal of Chinese Institute of Food Science and Technology,2017,17(1):31−38.
    [14]
    陈程莉. 黑枸杞花青素提取及微胶囊制备研究[D]. 重庆: 西南大学, 2020.

    CHEN C L. Extraction and microcapsule preparation of anthocyanin from Lycium ruthenicum Murr[D]. Chongqing: Southwest University, 2020.
    [15]
    李秀, 马利, 张圣卓, 等. 枸杞叶黄酮微胶囊的制备及其贮藏稳定性研究[J]. 中国食品添加剂,2020,31(6):10−18. [LI X, MA L, ZHANG S Z, et al. Study on preparation and storage stability of microcapsules of flavonoids from Lycium barbarum leaves[J]. China Food Additives,2020,31(6):10−18.
    [16]
    JLA B, MRA B, BNE A, et al. A new approach for the microencapsulation of curcumin by a spray drying method, in order to value food products[J]. Powder Technology,2020,362(C):428−435.
    [17]
    李雨田. 姜栀子配伍炮制的物质基础内涵研究[D]. 北京: 中国中医科学院, 2012.

    LI Y T. Study on the material basis of Gardenia jasminoids roasted with ginger juice[D]. Beijing: China Academy of Chinese Medical Sciences, 2012.
    [18]
    李小多, 李学刚, 张波, 等. 抑制血管紧张素转化酶的中药及活性成分的研究[J]. 食品工业科技,2013,34(1):49−52. [LI X D, LI X G, ZHANG B, et al. Study on angiotensin converting enzyme inhibition activity and active ingredient of traditional Chinese medicines[J]. Science and Technology of Food Industry,2013,34(1):49−52.
    [19]
    黄晓梅, 韦翠兰, 侯俊杰, 等. 大豆蛋白酶解产物的微胶囊化及理化性质表征[J]. 现代食品科技,2020,36(7):202−208. [HUANG X M, WEI C L, HOU J J, et al. Microencapsulation and characterization of soybean protein hydrolysates[J]. Modern Food Science and Technology,2020,36(7):202−208.
    [20]
    KHASHAYAR S, SEID M J. Application of gum arabic and maltodextrin for encapsulation of eggplant peel extract as a natural antioxidant and color source[J]. International Journal of Biological Macromolecules,2019,140:59−68. doi: 10.1016/j.ijbiomac.2019.08.133
    [21]
    王晓阳. 刺槐花中多酚类物质的提取工艺优化及其应用研究[D]. 济南: 山东师范大学, 2011.

    WANG X Y. Studies on the extraction process and application of polyphenols from Robinia pseudoacacia L. flowers[D]. Jinan: Shandong Normal University, 2011.
    [22]
    杨抒, 毛学英, 滕国新. 微囊化处理对乳清蛋白酶解物的苦味和吸湿性的改善作用研究[J]. 中国乳品工业,2013,41(8):4−7. [YANG S, MAO X Y, TENG G X. Improving effect of spray-drying encapsulation process on the bitter taste and stability of bioactive whey protein hydrolysate[J]. China Dairy Industry,2013,41(8):4−7. doi: 10.3969/j.issn.1001-2230.2013.08.001
    [23]
    王静, 李春, 曲国强, 等. OPO结构脂在模拟婴儿胃肠道消化环境中脂肪酸的释放特性[J]. 中国食品学报,2020,20(12):39−47. [WANG J, LI C, QU G Q, et al. Fatty acid release characteristics of OPO structural lipids in a simulated digestive environment of infant gastrointestinal tract[J]. Journal of Chinese Institute of Food Science and Technology,2020,20(12):39−47.
    [24]
    罗丽娟. ACE抑制肽的制备及肽的微胶囊化[D]. 南昌: 南昌大学, 2015.

    LUO L J. The preparation of ACE inhibitory peptides and its microencapsulation[D]. Nanchang: Nanchang University, 2015.
    [25]
    陈琨. 枸杞ACE抑制肽的提取、分离纯化、活性测定及其结构鉴定[D]. 银川: 宁夏医科大学, 2016.

    CHEN K. The iso-lation, purification, activity assay and structure determination of the ACE inhibitory peptides from Lycium barbarum L.[D]. Yinchuan: Ningxia Medical University, 2016.
    [26]
    朱晓琳, 刘跃钧, 陆敏, 等. 马兰中酚类的分离纯化及其抑制蛋白糖基化的研究[J]. 食品科学,2015,36(5):61−66. [ZHU X L, LIU Y J, LU M, et al. Separation, purifi cation and inhibitory effect on protein glycosylation of phenols in Kalimeris[J]. Food Science,2015,36(5):61−66. doi: 10.7506/spkx1002-6630-201505012
    [27]
    TOLUN A, ALTINTAS Z, ARTIK N. Microencapsulation of grape polyphenols using maltodextrin and gum arabic as two alternative coating materials: Development and characterization[J]. Journal of Biotechnology,2016,239:23−33. doi: 10.1016/j.jbiotec.2016.10.001
    [28]
    邱金双, 李陈雪, 牟景龙, 等. 中药微囊制剂研究进展[J]. 中国中医药信息杂志,2015,22(8):129−132. [QIU J S, LI C X, MOU J L, et al. Research progress of microcapsule preparation of traditional Chinese medicine[J]. Chinese Journal of Information on Traditional Chinese Medicine,2015,22(8):129−132. doi: 10.3969/j.issn.1005-5304.2015.08.040
    [29]
    POONAM, MISHRA, SANJAY, et al. Effect of maltodextrin concentration and inlet temperature during spray drying on physicochemical and antioxidant properties of amla(Emblica officinalis) juice powder[J]. Food & Bioproducts Processing,2014,92(3):252−258.
    [30]
    田媛. 喷雾干燥姜粉的加工工艺及速溶姜糖粉的研发[D]. 泰安: 山东农业大学, 2020.

    TIAN Y. Processing technology of spray-dried ginger powder and development of ginger sugar powder[D]. Taian: Shandong Agricultural University, 2020.
    [31]
    BAI X, LI C X, YU L, et al. Development and characterization of soybean oil microcapsules employing kafirin and sodium caseinate as wall materials[J]. LWT-Food Science and Technology,2019,111:235−241. doi: 10.1016/j.lwt.2019.05.032
    [32]
    HE J, RODRIGUEZ-SAONA L E, GIUSTI M M. Midinfrared spectroscopy for juice authentication-rapid differentiation of commercial juices[J]. J Agric Food Chemistry,2007,55(11):4443−4452. doi: 10.1021/jf062715c
    [33]
    BALLESTEROS L F, RAMIREZ M J, ORREGO C E, et al. Encapsulation of antioxidant phenolic compounds extracted from spent coffee grounds by freeze-drying and spray-drying using different coating materials[J]. Food Chemistry,2017(237):623−631.
    [34]
    张喜康, 赵宇慧, 刘军, 等. 枸杞不同生长期多糖的理化特性及结构分析[J]. 食品科学,2020,41(16):158−164. [ZHANG X K, ZHAO Y H, LIU J, et al. Physicochemical properties and structural analysis of Lycium barbarum L. polysaccharides at different growth stages[J]. Food Science,2020,41(16):158−164. doi: 10.7506/spkx1002-6630-20190427-353
    [35]
    PING L, PIZZI A, GUO Z D, et al. Condensed tannins from grape pomace: Characterization by FTIR and MALDI TOF and production of environment friendly wood adhesive[J]. Industrial Crops & Products,2012,40:13−20.
    [36]
    杨馥溪. 深度共熔溶剂提取花青素及其抗氧化性能评估和微胶囊制备的研究[D]. 广州: 华南理工大学, 2017.

    YANG F X. The research on efficient separation, purification and antioxidation of anthocyanins by using deep eutectic solvents and preparation of microcapsules[D]. Guangzhou: South China University of Technology, 2017.
    [37]
    YANUAR W, WIDJANARKO S B, WAHONO T. Characteristics and antioxidant stability of red fruit(Pandanus conoideus Lam) protein based microcapsule[J]. Jurnal Teknologi Pertanian,2007,8(2):127−135.
    [38]
    李杨, 徐静雯, 于静雯, 等. 不同蛋白微射流喷雾干燥制备鱼油微胶囊性能研究[J]. 农业机械学报,2020,51(3):350−357. [LI Y, XU J W, YU J W, et al. Effect of protein types on structure and stability of fish oil microcapsules[J]. Transactions of the Chinese Society for Agricultural Machinery,2020,51(3):350−357. doi: 10.6041/j.issn.1000-1298.2020.03.040
    [39]
    赵婕, 王明力, 汤翠, 等. 基于复合壁材的薏米糠油微胶囊制备及热稳定性研究[J]. 中国油脂,2018,43(3):70−74. [ZHAO J, WANG M L, TANG C, et al. Preparation and thermostability of adlay bran oil microcapsule based on compound wall materials[J]. China Oils and Fats,2018,43(3):70−74. doi: 10.3969/j.issn.1003-7969.2018.03.016
    [40]
    陈虎. 改性β-葡聚糖提高黑果枸杞花青素稳定性的技术及功能性评价[D]. 西宁: 青海大学, 2018.

    CHEN H. Technical and functional evaluation of improving the stability of anthocyanin of Lycium ruthenicum Murr by modified β-glucan[D]. Xining: Qinghai university, 2018.
    [41]
    罗鹏, 潘思轶, 何东平. 葵花籽ACE抑制肽的微胶囊制备工艺研究[J]. 粮食与油脂,2020,33(2):84−87. [LUO P, PAN S Y, HE D P. Preparation of microcapsule of ACE inhibitory peptides derived from sunflower seeds[J]. Cereals & Oils,2020,33(2):84−87. doi: 10.3969/j.issn.1008-9578.2020.02.022
  • Related Articles

    [1]LI Qiufeng, CHEN Jing, ZHAO Jingyi, WEI Xin, WANG Zhiqi, LIU Jidong. Efficient Soluble Expression and Fermentation Conditions of D-Allulose 3-Epimerase in Escherichia coli[J]. Science and Technology of Food Industry, 2022, 43(22): 136-143. DOI: 10.13386/j.issn1002-0306.2021120208
    [2]ZHU Xiao-wen, WANG Ze-jian, LI Liang, WU Jie-Qun, ZHUANG Ying-ping. Optimization of Medium and Feeding Process for L-Tryptophan Production Fermented by Escherichia coli[J]. Science and Technology of Food Industry, 2020, 41(2): 146-153. DOI: 10.13386/j.issn1002-0306.2020.02.024
    [3]XIE Lei, WU Wan-yi, LI Lu, XIE Xin-an, LI Yan. Determination of Pesticide Residues in Tea Broth by Solid Phase Extration Column of Dual Packing Materials with UV Spectrophotometry[J]. Science and Technology of Food Industry, 2019, 40(20): 256-261. DOI: 10.13386/j.issn1002-0306.2019.20.041
    [4]QUE Fa-xiu, CHEN Gang, GUO Yue-shan, ZHENG Shu-dan, JIAN Su-ping, WAN Ling. Fermentation Conditions Optimization of a Two-stage Culture for Enhancing Production of Lycopene by Neurospora crassa Using Response Surface Methodology[J]. Science and Technology of Food Industry, 2019, 40(17): 142-147. DOI: 10.13386/j.issn1002-0306.2019.17.023
    [5]QIAO Jun, TIAN Yan-jun, MA Yu-yue, JIANG Guo-zheng, ZHAO Xiang-ying, LIU Jian-jun. Culture medium and conditions optimization of L- aspartase- producing strains by Escherichia Coli HY-05C[J]. Science and Technology of Food Industry, 2016, (03): 139-142. DOI: 10.13386/j.issn1002-0306.2016.03.021
    [6]ZHENG Yue, PEI Qing-hui, GE Xi-zhen, TIAN Ping-fang. Overexpression glucose dehydrogenase can promote the growth of recombinant Escherichia coli[J]. Science and Technology of Food Industry, 2015, (22): 189-192. DOI: 10.13386/j.issn1002-0306.2015.22.031
    [7]LIU Hong-juan, WANG Teng-fei, TANG Dan-dan, WANG Sheng, DAI Kun, WANG Rui-ming. Optimization of fermentation conditions for trehalose synthase production by Escherichia coli using response surface method[J]. Science and Technology of Food Industry, 2015, (11): 181-187. DOI: 10.13386/j.issn1002-0306.2015.11.028
    [8]Succinic acid fermentation in different medium conditions by recombinant Escherichia coli[J]. Science and Technology of Food Industry, 2013, (06): 227-230. DOI: 10.13386/j.issn1002-0306.2013.06.028
    [10]发酵法桑汁饮料加工工艺的研究[J]. Science and Technology of Food Industry, 1999, (05): 35-37. DOI: 10.13386/j.issn1002-0306.1999.05.012
  • Cited by

    Periodical cited type(2)

    1. 张荣芳,闫洪波,李冉,宋聪,贾振华. 重组大肠杆菌全细胞催化合成D-甘油醛. 盐城工学院学报(自然科学版). 2024(01): 13-19 .
    2. 李少山,肖刚. 1, 4-丁二酸市场与生产技术分析. 合成纤维工业. 2023(01): 63-67+74 .

    Other cited types(1)

Catalog

    Article Metrics

    Article views PDF downloads Cited by(3)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return