Advances in the Study of Brain-Gut Axis and Intestinal Microorganisms in Neuropsychiatric Diseases

LI Ruiying; YAN Minghui; YOU Chunping

doi:10.13386/j.issn1002-0306.2020080250

Volume 42 Issue 18

Sep. 2021

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Science and Technology of Food Industry > 2021 > 42(18): 427-434. > DOI: 10.13386/j.issn1002-0306.2020080250

LI Ruiying, YAN Minghui, YOU Chunping. Advances in the Study of Brain-Gut Axis and Intestinal Microorganisms in Neuropsychiatric Diseases[J]. Science and Technology of Food Industry, 2021, 42(18): 427−434. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020080250.

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Advances in the Study of Brain-Gut Axis and Intestinal Microorganisms in Neuropsychiatric Diseases

1.
State Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Dairy Research Institute, Bright Dairy & Food Co., Ltd., Shanghai 200436, China
2.
College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China

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Received Date: August 25, 2020
Available Online: July 12, 2021

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Abstract

Abstract

There are a large number and a wide variety of enteric microorganism in the human intestinal tract, gut microbiota plays an important role in many physiological processes in the human body. More recently, studies have shown that intestinal flora can regulate the development and behavior of the body’s brain through the brain-gut axis, thus playing a key role in the prevention and treatment of autism spectrum disorders, schizophrenia, depression, anxiety disorders and so on. In this article, the bidirectional regulation mechanism of the brain- intestine axis is described, the changes and possible mechanisms of the factors directly related to various mental disorders are summarized, and the recent domestic and foreign research progress on intestinal microbial changes in various mental diseases is further generalized, which provide a new idea and theoretical reference for the study of early probiotics intervention treatment for patients with mental diseases mentioned above.
- gut microbiota,
- neuropsychiatric diseases,
- mechanism,
- gut-brain axis

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References

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