SA Yi, CHEN Xiaoyi. Record of Vitamin Mineral Supplement in China and Its Future Development Trend[J]. Science and Technology of Food Industry, 2021, 42(3): 320-325,337. DOI: 10.13386/j.issn1002-0306.2020040243
Citation: SA Yi, CHEN Xiaoyi. Record of Vitamin Mineral Supplement in China and Its Future Development Trend[J]. Science and Technology of Food Industry, 2021, 42(3): 320-325,337. DOI: 10.13386/j.issn1002-0306.2020040243

Record of Vitamin Mineral Supplement in China and Its Future Development Trend

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  • Received Date: April 20, 2020
  • Available Online: February 02, 2021
  • In July 2016,the dietary supplement implemented a dual registration and filing system. The first dietary supplement to go on record are vitamins and minerals. So far,the dietary supplement has been in place for three years. The number of registered vitamin mineral products has reached more than 5,100,exceeding the total number of previously approved vitamin mineral products. According to the products on record,supplement contains calcium,vitamin C,vitamin D and other products are more popular. Based on the materials used for the record,calcium carbonate,vitamin D3,l-ascorbic acid are commonly used compounds. Look at the dosage form of the registered product,tablets and soft capsules account for 85 percent of recorded products. In this paper,the basic information of dietary supplement products in the past 3 years,including the types of raw materials used,compatibility,product dosage forms,etc. According to the consumption information prompt of vitamin mineral products and the analysis of the approved products in China,it is suggested that consumers should rationally choose nutrient supplement products. Finally,it is suggested that the production enterprise,as the responsible person of product quality,should ensure the quality controllability of the product during the research and development and production according to the development trend of dietary supplement.
  • [1]
    国家食品药品监督管理总局.保健食品备案工作指南(试行)[Z].2017-05-02.
    [2]
    保健食品备案管理信息系统[EB/OL].[2020-06-03]. http://bagl.zybh.org.cn:18000/acl/login/welcome.do.
    [3]
    夏维波.补钙和维生素D对骨骼健康的必要性[J].中华骨质疏松和骨矿盐疾病杂志,2018,11(1):20-25.
    [4]
    Reid IR,Bolland MJ. Controversies in medicine:The role of calcium and vitamin D supplements in adults[J]. Med J Aust,2019,211(10):468-473.
    [5]
    朱芳玲,朱群英,黄慧娟.不同剂量复方硫酸亚铁叶酸片治疗妊娠期缺铁性贫血的临床研究[J].药品评价,2019,16(22):85-86.
    [6]
    Kassa ZY,Awraris T,Daba AK,et al. Compliance with iron folic acid and associated factors among pregnant women through pill count in Hawassa city,South Ethiopia:a community based cross-sectional study[J]. Reprod Health,2019,16(1):14.
    [7]
    Cantorna MT,Snyder L,Arora J. Vitamin A and vitamin D regulate the microbial complexity,barrier function,and the mucosal immune responses to ensure intestinal homeostasis[J]. Crit Rev Biochem Mol Biol,2019,54(2):184-192.
    [8]
    Riccio P,Rossano R. Diet,gut microbiota,and vitamins D+A in multiple sclerosis[J]. Neurotherapeutics,2018,15(1):75-91.
    [9]
    Ivancovsky-Wajcman D,Fliss-Isakov N,Salomone F,et al. Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease[J]. Dig Liver Dis,2019,51(12):1698-1705.
    [10]
    Stunes AK,Syversen U,Berntsen S,et al. High doses of vitamin C plus E reduce strength training-induced improvements in areal bone mineral density in elderly men[J]. Eur J Appl Physiol,2017,117(6):1073-1084.
    [11]
    Rogerson D. Vegan diets:Practical advice for athletes and exercisers[J]. J Int Soc Sports Nutr,2017,14:36.
    [12]
    van Dronkelaar C,van Velzen A,Abdelrazek M,et al. Minerals and sarcopenia;The role of calcium,iron,magnesium,phosphorus,potassium,selenium,sodium,and zinc on muscle mass,muscle strength,and physical performance in older adults:A systematic review[J]. J Am Med Dir Assoc,2018,19(1):6-11.
    [13]
    Kidd PM. Vitamins D and K as pleiotropic nutrients:Clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy[J]. Altern Med Rev,2010,15(3):199-222.
    [14]
    Karpiński M,Popko J,Maresz K,et al. Roles of vitamins D and K,nutrition,and lifestyle in low-energy bone fractures in children and young adults[J]. J Am Coll Nutr,2017,36(5):399-412.
    [15]
    Boulier A,Schwarz J,Lespesailles E,et al. Combination of micellar casein with calcium and vitamins D2 and K2improves bone status of ovariectomized mice[J]. Osteoporos Int,2016,27(10):3103-3112.
    [16]
    Jayalakshmi S,Platel K. Supplemental levels of iron and calcium interfere with repletion of zinc status in zinc-deficient animals[J]. Food Funct,2016,7(5):2288-2293.
    [17]
    国家食品药品监督管理局.营养素补充剂申报与审评规定[Z].2005-05-20.
    [18]
    全国人民代表大会常务委员会.中华人民共和国食品安全法[Z].2019-02-08.
    [19]
    国家食品药品监督管理总局.保健食品注册与备案管理办法[Z].2016-02-26.
    [20]
    龚玉琼,钟国清.柠檬酸钙的制备与应用进展[J].精细与专用化学品,2016,24(7):12-16.
    [21]
    Kim J,Choi J,Kwon SY,et al. Association of multivitamin and mineral supplementation and risk of cardiovascular disease:A systematic review and meta-analysis[J]. Circ Cardiovasc Qual Outcomes,2018,11(7):e004224.
    [22]
    Biesalski HK,Tinz J. Multivitamin/mineral supplements:Rationale and safety[J]. Nutrition,2017,36:60-66.
    [23]
    Kennedy DO. B vitamins and the brain:Mechanisms,dose and efficacy-a review[J]. Nutrients,2016,8(2):68.
    [24]
    Mikkelsen K,Apostolopoulos V. B vitamins and ageing[J]. Subcell Biochem,2018,90:451-470.
    [25]
    Straub DA. Calcium supplementation in clinical practice:A review of forms,doses,and indications[J]. Nutr Clin Pract,2007,22(3):286-296.
    [26]
    Je SH,Joo NS,Choi BH,et al. Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral density in Korean postmenopausal women over sixty-years-old[J]. J Korean Med Sci,2011,26(8):1093-1098.
    [27]
    Quesada Gómez JM,Blanch Rubió J,Díaz Curiel M,et al. Calcium citrate and vitamin D in the treatment of osteoporosis[J].Clin Drug Investig,2011,31(5):285-298.
    [28]
    Palermo A,Naciu AM,Tabacco G,et al. Calcium citrate:From biochemistry and physiology to clinical applications[J]. Rev Endocr Metab Disord,2019,20(3):353-364.
    [29]
    李桂英,张中朋.膳食营养补充剂行业发展情况(一)[J].精细与专用化学品,2019,27(9):1-10.
    [30]
    Chiodini I,Bolland MJ. Calcium supplementation in osteoporosis:useful or harmful?[J]. Eur J Endocrinol,2018,178(4):D13-D25.
    [31]
    Kaats GR,Preuss HG,Stohs S,et al. A 7-year longitudinal trial of the safety and efficacy of a vitamin/mineral enhanced plant-sourced calcium supplement[J]. J Am Coll Nutr,2016,35(2):91-99.
    [32]
    Di Vincenzo A,Tana C,El Hadi H,et al. Antioxidant,anti-inflammatory,and metabolic properties of tocopherols and tocotrienols:Clinical implications for vitamin E supplementation in diabetic kidney disease[J]. Int J Mol Sci,2019,20(20):5101.
    [33]
    Panebianco C,Eddine FBN,Forlani G,et al. Probiotic Bifidobacterium lactis,anti-oxidant vitamin E/C and anti-inflammatory dha attenuate lung inflammation due to pm2.5 exposure in mice[J]. Benef Microbes,2019,10(1):69-75.
    [34]
    Boyle NB,Lawton C,Dye L. The effects of magnesium supplementation on subjective anxiety and stress-a systematic review[J].Nutrients,2017,9(5):429.
    [35]
    Tangvoraphonkchai K,Davenport A. Magnesium and cardiovascular disease[J]. Adv Chronic Kidney Dis,2018,25(3):251-260.
    [36]
    Rapola JM,Virtamo J,Ripatti S,et al. Effects of alpha tocopherol and beta carotene supplements on symptoms,progression,and prognosis of angina pectoris[J]. Heart,1998,79(5):454-458.
    [37]
    Rapola JM,Virtamo J,Haukka JK,et al. Effect of vitamin E and beta carotene on the incidence of angina pectoris. A randomized,double-blind,controlled trial[J]. JAMA. 1996,275(9):693-698.
    [38]
    Penniston KL,Tanumihardjo SA. The acute and chronic toxic effects of vitamin[J]. A Am J Clin Nutr,2006,83(2):191-201.
    [39]
    Melhus H,Michaëlsson K,Kindmark A,et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture[J]. Ann Intern Med,1998,129(10):770-778.
    [40]
    Slotki I,Cabantchik ZI. The labile side of iron supplementation in CKD[J]. J Am Soc Nephrol,2015,26(11):2612-2619.
    [41]
    Barton JC,Lee PL,West C,et al. Iron overload and prolonged ingestion of iron supplements:Clinical features and mutation analysis of hemochromatosis-associated genes in four cases[J]. Am J Hematol,2006,81(10):760-767.
    [42]
    Tankeu AT,Ndip Agbor V,Noubiap JJ. Calcium supplementation and cardiovascular risk:A rising concern[J]. J Clin Hypertens(Greenwich),2017,19(6):640-646.
    [43]
    Li K,Wang XF,Li DY,et al. The good,the bad,and the ugly of calcium supplementation:a review of calcium intake on human health[J]. Clin Interv Aging,2018,13:2443-2452.
    [44]
    Ronis MJJ,Pedersen KB,Watt J. Adverse effects of nutraceuticals and dietary supplements[J]. Annu Rev Pharmacol Toxicol,2018,58:583-601.
    [45]
    国家食品药品监督管理总局.保健食品注册审评审批细则[Z].2016-11-14.
    [46]
    国家食品药品监督管理总局.保健食品申请服务指南[Z].2016-12-19.
    [47]
    国家食品药品监督管理总局,国家卫生和计划生育委员会,国家中医药管理局.保健食品原料目录(一)[Z].2016-12-27.
    [48]
    中国共产党第十八届五中全会.健康中国2030规划纲要[Z].2016-10-25.
    [49]
    中国共产党第十八届五中全会.国民营养计划(2017-2030年)[Z].2016-10-25.
    [50]
    中华人民共和国卫生部.GB 14880-2012食品营养强化剂使用标准[S].北京:中国标准出版社,2012.
    [51]
    国家市场监督管理总局.保健食品原料目录与保健功能目录管理办法[Z].2019-08-02.
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