Research Progress of Anti-tumor and Anti-metastasis Effects of Cordycepin

CUI Linlin; YUAN Tian; WANG Yang; LI Yang; SHEN Guanghuan

doi:10.13386/j.issn1002-0306.2020040172

Volume 42 Issue 4

Feb. 2021

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Science and Technology of Food Industry > 2021 > 42(4): 356-362. > DOI: 10.13386/j.issn1002-0306.2020040172

CUI Linlin, YUAN Tian, WANG Yang, LI Yang, SHEN Guanghuan. Research Progress of Anti-tumor and Anti-metastasis Effects of Cordycepin[J]. Science and Technology of Food Industry, 2021, 42(4): 356-362. DOI: 10.13386/j.issn1002-0306.2020040172

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Research Progress of Anti-tumor and Anti-metastasis Effects of Cordycepin

CUI Linlin^1,2,
YUAN Tian^1,2,
WANG Yang^1,2,
LI Yang^1,2,
SHEN Guanghuan^1,2, ,

1. Harbin University of Commerce College of Pharmacy, Harbin 150076, China;
2. Heilongjiang Key Laboratory of Drugs for the Prevention and Treatment of Senile Disease, Harbin 150076, China

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Received Date: April 14, 2020
Available Online: March 01, 2021

Graphical Abstract

Abstract

Abstract

Cancer is the number one killer of death,cordycepin can inhibit the proliferation and migration of tumor cell,and has the advantages of small side effects and high drug resistance. In recent years,the use of modern computer technology to find its anti-tumor mechanism and potential biological targets will open up a new horizons for the exploration of cordycepin’s anti-tumor mechanism and greatly promote the application of cordycepin in anti-tumor.Cordycepin not only induces apoptosis by regulating tumor-related signaling pathways,causes cycle arrest,targeted intervention of tumor stem cells(CSCs)inhibits tumor growth,and also inhibits tumor metastasis by regulating the tumor microenvironment. The contents of this review will provide a reference that is for better research on the antitumor mechanism of cordycepin in later period.
- cordycepin,
- anti-tumor,
- cycle arrest,
- apoptosis,
- anti-metastasis,
- molecular biology

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References

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