Comparative Research on Antioxidant, Bacteriostatic and Antitumor Activities of Ginger and Vinegar Soaked Ginger

The antioxidant, bacteriostatic and antitumor activities of ginger oil and ginger ethanol extracts of ginger and vinegar soaked ginger were studied in this paper. The antioxidant activities (DPPH free radical, ABTS⁺ free radical, hydroxyl radical scavenging and measurement of total reduction capacity) of two kinds of ginger were evaluated with ascorbic acid as the positive control. The bacteriostatic activity of two kinds of ginger on several common pathogenic bacteria was studied by 96-well plate microdilution method. The antitumor effect of two types of ginger extracts on tumor cells including HCT116 (human colon cancer cell), HepG2 (human liver cancer cell) and Skov3 (ovarian carcinoma cells) were studied. The results showed that the antioxidant activity of vinegar soaked ginger was better than that of ginger in general, and the scavenging effect of vinegar ginger oil on hydroxyl radical (IC₅₀ 0.28 mg/mL) was obviously stronger than that of ginger oil (IC₅₀ 0.42 mg/mL).Ginger and vinegar soaked ginger extracts had certain antibacterial effect, the bacteriostatic vinegar soaked ginger oil effect of was slightly better than ginger oil, the best was vinegar soaked ginger oil on Staphylococcus aureus inhibition (156.25 μg/mL).The antitumor activity of ginger and vinegar soaked ginger extracts had no significant differences. So vinegar soaked ginger is superior to ginger in antioxidant and bacteriostatic activities.