Research Development of the Bioactive Peptides Based on Bioinformatics

The traditional method of separation,purification and identification of bioactive peptides is the method of time-consuming and difficult,and lack of rapid and accurate activity evaluation. How to obtain the active peptides quickly and efficiently is still a hard work in the research of active peptides. In recent years,the rapid development of bioinformatics provides methods and software tools for the analysis of biological big data,which is gradually being applied to the study of biologically active peptides. Firstly,this paper summarizes the difficulties of bioactive peptides on the separation,purification and activity evaluation by traditional methods. Secondly,it focuses on the bioinformatics technology during the simulation of enzymatic hydrolysis,the activity prediction of enzymatic products and selection of precursor proteins,the recognition and the structure-activity relationship of active peptide. It could provide references for the wide application of bioinformatics in bioactive peptide.