In vitro inhibitory effects of polyphenol extracts from Euryale ferox seed coat on α-glucosidase and α-amylase activities

WU Cheng-ying; WU Qi-nan; WANG Hong; FAN Xiu-he

doi:10.13386/j.issn1002-0306.2015.16.010

WU Cheng-ying, WU Qi-nan, WANG Hong, FAN Xiu-he. In vitro inhibitory effects of polyphenol extracts from Euryale ferox seed coat on α-glucosidase and α-amylase activities[J]. Science and Technology of Food Industry, 2015, (16): 91-94. DOI: 10.13386/j.issn1002-0306.2015.16.010

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In vitro inhibitory effects of polyphenol extracts from Euryale ferox seed coat on α-glucosidase and α-amylase activities

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The inhibitory effects of total polyphenols extracts from Euryale ferox seed coat against α-glucosidase and α-amylase were studied through the in vitro testing of inhibition rate and inhibition kinetics. The results showed that the total polyphenols exhibited strong inhibitory effects against α-glucosidase and α-amylase in vitro with dose-effect relationship and the IC50 were 0.08 mg/m L and 0.30 mg/m L,respectively. The inhibition type was reversible and competitive inhibitor. In conclusion,Euryale ferox seed coat would be a potential source for a hypoglycemic functional food or medicine.

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In vitro inhibitory effects of polyphenol extracts from Euryale ferox seed coat on α-glucosidase and α-amylase activities

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