Hepatoprotective effects of Schisandra chinesis (Turcz.) Bail juice on carbon tetrachloride induced acute liver damage in rats

The protective effects of Schisandra chinensis (Turcz.) Bail juice against liver damage in carbon tetrachloride (CCl4) -induced acute hepatotoxicity in rats were studied. Wista rats were orally fed with detected samples. The activities of ALT, AST and AKP in serum and GSH-Px, SOD and CAT in live were detected. The content of MDA in liver was also tested. The liver tissue pathological change was observed. The results showed that S. chinensis juice could significantly decrease the activities of AST and AKP in serum and significantly increase the activities of GSH-Px, SOD and CAT in liver. The content of MDA in liver was also significantly decreased. Compared with the model group the pathological change in liver of each S. chinensis juice group was significantly improved. The results proved that S. chinensis fruit juice had a protective effect on CCl4-induced acute liver damage in rats. This provided the basis for S. chinensis juice application in health food.