In vitro evaluation of antihypertensive activity on ACE inhibitory peptides derived from Amaranth

ZHOU Jia-hua; LIU Chun-ying; ZHAO Yi; HE Ji-guo; CHEN Fei-ping

doi:10.13386/j.issn1002-0306.2014.08.023

ZHOU Jia-hua, LIU Chun-ying, ZHAO Yi, HE Ji-guo, CHEN Fei-ping. In vitro evaluation of antihypertensive activity on ACE inhibitory peptides derived from Amaranth[J]. Science and Technology of Food Industry, 2014, (08): 142-144. DOI: 10.13386/j.issn1002-0306.2014.08.023

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In vitro evaluation of antihypertensive activity on ACE inhibitory peptides derived from Amaranth

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According to the angiotensin-converting enzyme (ACE) on blood pressure regulation mechanism, furan acryloyl tripeptide (FAPGG) as it was angiotensinⅠmimetic. It was established in vitro trypsin digestion system and simulated rat liver mixed function oxidase (MFO) analog liver metabolism system. Untreated ACE inhibitory peptides of amaranth IC50valued 1mg/mL, digestion and incubated in vitro after treatment ACE inhibitory peptides IC50 valued 10mg/mL.

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In vitro evaluation of antihypertensive activity on ACE inhibitory peptides derived from Amaranth

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