Research progress in wheat α-gliadin peptides related to celiac disease

YU Feng-lian; LI Su-yun; YUAN Juan-li; CHEN Hong-bing; GAO Jin-yan

doi:10.13386/j.issn1002-0306.2014.02.065

YU Feng-lian, LI Su-yun, YUAN Juan-li, CHEN Hong-bing, GAO Jin-yan. Research progress in wheat α-gliadin peptides related to celiac disease[J]. Science and Technology of Food Industry, 2014, (02): 364-368. DOI: 10.13386/j.issn1002-0306.2014.02.065

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Research progress in wheat α-gliadin peptides related to celiac disease

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Celiac disease was an immunne disorder induced by wheat gliadin peptides in genetically susceptible population, and this immune reaction includes non-specific immune responses and specific immune response, depending on the trigger mechanism.α-gliadin was rich in wheat gliadin, and it was the main proteins in the cause of celiac disease.Moreover, α-gliadin peptides could be divided into two categories :non-specific toxicity of peptides and immunity peptide.Among them, p57-89 peptide of α-gliadin was the major immunity peptide induced T cell-mediated inflammatory reactions, and p31-43 and p31-49 peptides were the main toxicity peptide.

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Research progress in wheat α-gliadin peptides related to celiac disease

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