Triflumuron microcapsules: preparation, characterization and control released properties

In order to improve pesticide biological security and sustained effect in the ecological environment, the triflumuron (TFM) was directly encapsulated through layer-by-layer (LbL) self-assembly method.The results showed that the optimum conditions screened by orthogonal experiments for preparing TFM microencapsulation were 3.0g /L sodium alginate, 2.0g /L nature chitosan, 1.0g /L TFM and 2.0g /L CaCl 2.The effect of chitosan concentration was most significant among those4elements evaluated in the orthogonal experiment.The encapsulation efficiency and drug loading of the microcapsule prepared with optimum conditions were 77.4% and 75.2% respectively.The coated colloids were characterized using confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) .For the TFM microcapsules prepared with the optimized system, the surface was smooth and there is no drug dissolution, the mean grain size was6μm, their Zeta potential was-12.5mV.The in vitro release experiment revealed that the controlled-release property of TFM microcapsules, prepared by this method, significantly enhanced with the increasing of the cladding layers.