Study on the degradation conditions of fucoidan from Sargassum henslowianum

The degradation of SF1 from Sargassum hemiphyllum was depended on ultrasound.Reducing sugar release was the indicator to reflect the relativity among ultrasound power, temperature and time during the degradation.Response surface methodology was used to optimize the degradation conditions.The result showed that the behavior of the system was explained by a quadratic equation between reducing sugar release and factors (ultrasonic power, temperature and time) .The result showed degradation conditions were ultrasonic power 350W, temperature 50℃, time 59min, and the reducing sugar release was 32.86μg/mL.Polysaccharide content, fucose content, sulfate group content and uronic acid of SF1' were 70.55%, 37.62%, 36.12% and 6.15%.