Abstract: To optimize the extraction technology and antioxidant activity of polyphenols from purple passionfruit leaves. On the basis of a single factor test,the material to solvent ratio,extraction time,ultrasonic power and ultrasonic temperature were the factors,and the Box-Beheken was used to design test program. The optimal extraction technology was as follows: Solvent to material ratio 36∶1 mL/g,extraction time 54 min,ultrasonic power 350 W and temperature 70 ℃. Under the above conditions,the extraction amount of polyphenols from purple passionfruit leaves was(13.19±0.17) mg/g. The test of antioxidant activity showed that the polyphenols from purple passionfruit leaves had better antioxidant activity,and half inhibition concentrations(IC₅₀)of DPPH and hydroxyl radicals were 0.058 mg/mL and 0.144 mg/mL,respectively.