Abstract: Cronobacter is a food-borne pathogen which seriously threatens the health of infants. It is mainly transmitted through infant foods,which may cause infants to suffer from fatal diseases such as meningitis and necrotizing enterocolitis. Cronobacter can survive in special environments such as dryness,high temperature and so on where are generally not viable for microorganisms. In order to understand the characteristics of Cronobacter in special environments,the current progress on Cronobacter from the perspectives of drought resistance,heat resistance,acid-base tolerance and drug resistance is introduced in this paper. And this is of great significance for the safety of food production,especially the production of food for infants,and the provision of medical methods for clinical treatment to ensure human health.