Abstract: After laying from cloaca, there are dirt and bacteria on the eggshell, which may be harmful for consumers’ health. The only way to prevent eggshell contamination is to clean and disinfect rapidly after laying, so the disinfection of eggshell is a necessary step for clean egg production. To filter out better egg disinfection methods , in this experiment , several affordable , easy - operatable chemical reagents ( sodium hypochlorite , potassium permanganate , sodium hydroxide , sodium carbonate ) and physical methods ( UV sterilization, pasteurization, boiling water sterilization) were chosen for eggshell sterilization treatment, and compared with the total number of colonies, the number of salmonella determination, and the preservation effect during storage at 37℃ with control group. The results of sterilization experiment and storage experiment showed that sodium hypochlorite treatment ( chemical sterilization method ) and UV sterilization treatment (physical sterilization method) had good bactericidal effect of eggshell surface.