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中国精品科技期刊2020
康小红, 王凡, 陈建国, 韩雪, 张兰威. 嗜热链球菌MN-ZLW-002体外益生特性与安全性分析[J]. 食品工业科技, 2020, 41(15): 124-128. DOI: 10.13386/j.issn1002-0306.2020.15.020
引用本文: 康小红, 王凡, 陈建国, 韩雪, 张兰威. 嗜热链球菌MN-ZLW-002体外益生特性与安全性分析[J]. 食品工业科技, 2020, 41(15): 124-128. DOI: 10.13386/j.issn1002-0306.2020.15.020
KANG Xiao-hong, WANG Fan, CHEN Jian-guo, HAN Xue, ZHANG Lan-wei. The Probiotic Properties in Vitro and Safety Analysis of Streptococcus thermophiles MN-ZLW-002[J]. Science and Technology of Food Industry, 2020, 41(15): 124-128. DOI: 10.13386/j.issn1002-0306.2020.15.020
Citation: KANG Xiao-hong, WANG Fan, CHEN Jian-guo, HAN Xue, ZHANG Lan-wei. The Probiotic Properties in Vitro and Safety Analysis of Streptococcus thermophiles MN-ZLW-002[J]. Science and Technology of Food Industry, 2020, 41(15): 124-128. DOI: 10.13386/j.issn1002-0306.2020.15.020

嗜热链球菌MN-ZLW-002体外益生特性与安全性分析

The Probiotic Properties in Vitro and Safety Analysis of Streptococcus thermophiles MN-ZLW-002

  • 摘要: 本研究对分离甘南地区的嗜热链球菌MN-ZLW-002进行了体外益生功能和安全性分析。结果显示,MN-ZLW-002对pH2.0及pH3.0的人工胃液耐受性较好,但对0.3%胆盐条件耐受性较弱;菌株MN-ZLW-002对胆固醇的降解率为42.66%±2.11%,对氯霉素、庆大霉素、链霉素、四环素、万古霉素、卡那霉素、青霉素、红霉素和克林霉素均敏感,且MN-ZLW-002急性经口毒性属无毒。综合上述结果,MN-ZLW-002具有良好的模拟胃液耐受性、较强的胆固醇降解能力,且安全无毒,可作为功能型发酵食品原料进行开发,具有巨大的商业价值。

     

    Abstract: In this study, the probiotic property in vitro and safety of Streptococcus thermophilus MN-ZLW-002 isolated from Gannan area were analyzed. The results showed that MN-ZLW-002 was well tolerated to artificial gastric juice at pH2.0 and pH3.0, but weakly tolerated to 0.3% bile salt. The cholesterol degradation rate of strain MN-ZLW-002 was 42.66%±2.11%. MN-ZLW-002 was sensitive to chloramphenicol, gentamicin, streptomycin, tetracycline, vancomycin, kanamycin, penicillin, erythromycin and clindamycin. Meanwhile, MN-ZLW-002 acute transoral toxicity was nontoxic. In a conclusion, MN-ZLW-002 is not only non-toxic and has a good tolerance to simulated gastric juice, but also has a strong ability to degrade cholesterol. It can be developed as a functional fermented food raw material and has a great commercial value.

     

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