Abstract: The incidence of cnronic kidney disease is increasing year by year in our country, and the low protein diet is one of the effective dietotherapy methods to delay the development of chronic kidney disease. In this paper, the research methods of low protein adjusted rice, which had been paid more and more attention in recent years, were reviewed and prospected, and the advantages and disadvantages of the methods including breeding cultivation, physical methods, chemical methods and biodegradation were analyzed.The method of biodegradation of whole rice protein can greatly reduce the protein content while maintaining the original integrity and taste of rice, and the product is more suitable for long-term consumption of nephrotic patients. In China, about 2/3 of the population live on rice, and the number of patients with kidney disease is increasing, but the amount of low protein products are too few to popularize, so it is very promising to develop the low protein rice in accordance with the diet habit of patients from the improvement of the staple food.