Abstract: To study the effect of vibrational frequency on the quality of melon fruit and pulp cells. To explore the effects of 6,9,12,15,18,24 Hz vibrations on the quality of melons and the degree of damage through the texture profile analysis to study the texture changes of muskmelons. The results showed that the hardness,resilience,cohesiveness and chewiness of the muskmelons were significantly lower than the original group. The cell membrane permeability of the muskmelons was significantly higher than the control group. It was found that after the vibration treatment,the cells were not tightly connected and atrophied. In the storage period,the samples were vibrated at 6 and 9 Hz,the values of hardness,resilience,cohesiveness and chewiness of melons respectively dropped sharply to their minimum values,and the cell membrane had the highest permeability. The vibration treatment significantly reduced the quality of muskmelons,which could cause fruit cell damage,and had no benefit to the melon’s preservation. In the actual transportation process,we should better use the buffer packaging try to avoid vibration.