Abstract: The study was the detection and comparative analysis of the contents of carbohydrate,protein,fat,ash,amino acids,fatty acid,anthocyanin,polysaccharides and polyphenol and the antioxidant activity of anthocyanin extracting solution of wild Lycium ruthenicum from different regions.The results showed that the contents of carbohydrate,protein,fat and ash of the wild Lycium ruthenicum were 69.55% ~ 77.14%,10.76% ~ 14.72%,3.90% ~ 6.89% and 6.63% ~ 10.99%,respectively. There was certain gap of the contents in different regions.The Lycium ruthenicum contained 17 kinds of amino acids.The total amino acid and unsaturated fatty acid were 7.459% ~ 10.514% and 73.00% ~ 85.29%,respectively. The highest ratio of unsaturated fatty acid to total fatty acid were 85.29% in Lycium ruthenicum from Alatengaobao Inner Mongolia. The average content of anthocyanin,polysaccharides and polyphenol were 2.29%,5.22% and 3.94%,respectively. The DPPH· and ·OH scavenging activity of anthocyanin extracting solution were both highest of the Lycium ruthenicum from Alatengaobao Inner Mongolia.The reducing power of anthocyanin extracting solution was 2.94 of the Lycium ruthenicum from Sumber Mongolia. Therefore,the Lycium ruthenicum,in different regions,were the more nutritious food and differences.