Abstract: The tonifying Yang and anti- anoxia effects of Chongfengyihao fruit coffee drink ( CFCD) was studied to provide evidences in pharmacodynamics experiment for further investigation. Orchidectomized and normal male rats were administered with CFCD by gavage, and capture incubation period, capture times, ejaculation times, capture female rat cases and ejaculation male rat cases were observed.Meanwhile the content of testosterone in serum of rats was measured.Seminal vesicle, prostate and anal muscle were weighted and the viscera index were calculated; Mouse were administered with CFCD by gavage, normal pressure hypoxia test, the survival time of sodium nitrite poisoning, and acute cerebral ischemic anoxic survival test were employed to monitor CFDC's on enhancing anoxia ability.Results indicated that CFCD at high dose shortened capture incubation period ( p < 0.05) , increased capture times ( p < 0.05) and ejaculation times ( p < 0.05) in orchidectomized male rats; wihle CFCD at both high and middle dose prolonged the latent period of normal pressure hypoxia ( p < 0.05) and the survival time of acute cerebral ischemic anoxic ( p < 0.001, p < 0.05) .This research suggested that CFCD had tonifying Yang and anti-anoxia effects.